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Q3IIW1 (Q3IIW1_PSEHT) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase HAMAP MF_00387
Short name=UDP-N-acetylglucosamine acyltransferase HAMAP MF_00387
EC=2.3.1.129 HAMAP MF_00387
Gene names
Name:lpxA HAMAP MF_00387 EMBL CAI87080.1
Ordered Locus Names:PSHAa2024
OrganismPseudoalteromonas haloplanktis (strain TAC 125) [Complete proteome] [HAMAP]
Taxonomic identifier326442 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Pseudoalteromonadaceae › Pseudoalteromonas

Protein attributes

Sequence length256 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. HAMAP MF_00387 SAAS SAAS010137

Catalytic activity

(R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] + UDP-N-acetylglucosamine = [acyl-carrier-protein] + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine. HAMAP MF_00387 SAAS SAAS010137

Pathway

Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 1/6. HAMAP MF_00387 SAAS SAAS010137

Subunit structure

Homotrimer By similarity. HAMAP MF_00387 SAAS SAAS010137

Subcellular location

Cytoplasm By similarity HAMAP MF_00387.

Sequence similarities

Belongs to the transferase hexapeptide repeat family. LpxA subfamily. HAMAP MF_00387

Sequences

Sequence LengthMass (Da)Tools
Q3IIW1 [UniParc].

Last modified November 8, 2005. Version 1.
Checksum: 8C9513301D5BF787

FASTA25627,485
        10         20         30         40         50         60 
MIHPTAIIEP GATLGSNVSV GPYSYIGNDV VIGDNCIIES HVVVKGPSTI GSGNHIFQFA 

        70         80         90        100        110        120 
SVGEACQDKK YNNEPTSLTI GDNNIIRECV TIHRGTIQDQ GVTIIGSNNL FMAYTHVAHD 

       130        140        150        160        170        180 
AVIGDNVIFA NNASVAGHVH IGDWVILAGN SGIHQFCKVG AHAFVGMYSA INKDVPPFVT 

       190        200        210        220        230        240 
TIGIPAGPVA INTEGMKRRG FQSDEIMAVR RAYKVFYRKS LGVDEAIESL SEDAQKYPAV 

       250 
QLMIDFVKSS ERGIVR

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References

[1]"Coping with cold: the genome of the versatile marine Antarctica bacterium Pseudoalteromonas haloplanktis TAC125."
Medigue C., Krin E., Pascal G., Barbe V., Bernsel A., Bertin P.N., Cheung F., Cruveiller S., D'Amico S., Duilio A., Fang G., Feller G., Ho C., Mangenot S., Marino G., Nilsson J., Parrilli E., Rocha E.P.C. expand/collapse author list , Rouy Z., Sekowska A., Tutino M.L., Vallenet D., von Heijne G., Danchin A.
Genome Res. 15:1325-1335(2005) [PubMed: 16169927] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CR954246 Genomic DNA. Translation: CAI87080.1.
RefSeqYP_340523.1. NC_007481.1.

3D structure databases

ProteinModelPortalQ3IIW1.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ3IIW1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3710255.
GenomeReviewsGene locus PSHAa2024 in contig CR954246_GR.
KEGGpha:PSHAa2024.
NMPDRfig|326442.4.peg.1208.
PATRIC32297647. VBIPseHal105694_1952.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1043.
HOGENOMHBG659295.
OMAREFCTFN.
PhylomeDBQ3IIW1.
ProtClustDBPRK05289.

Enzyme and pathway databases

BioCycPHAL326442:PSHAA2024-MONOMER.

Family and domain databases

HAMAPMF_00387. LpxA.
[Tree]
InterProIPR001451. Hexapep_transf.
IPR018357. Hexapep_transf_CS.
IPR010137. Lipid_A_lpxA.
IPR011004. Trimer_LpxA-like.
[Graphical view]
KOK00677.
PfamPF00132. Hexapep. 5 hits.
[Graphical view]
PIRSFPIRSF000456. UDP-GlcNAc_acltr. 1 hit.
SUPFAMSSF51161. Trimer_LpxA_like. 1 hit.
TIGRFAMsTIGR01852. Lipid_A_lpxA. 1 hit.
PROSITEPS00101. HEXAPEP_TRANSFERASES. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ3IIW1_PSEHT
AccessionPrimary (citable) accession number: Q3IIW1
Entry history
Integrated into UniProtKB/TrEMBL: November 8, 2005
Last sequence update: November 8, 2005
Last modified: December 14, 2011
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info