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Q3IIQ2

- PUR5_PSEHT

UniProt

Q3IIQ2 - PUR5_PSEHT

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Protein
Phosphoribosylformylglycinamidine cyclo-ligase
Gene
purM, PSHAa1947
Organism
Pseudoalteromonas haloplanktis (strain TAC 125)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Purine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPHAL326442:GJIU-1996-MONOMER.
UniPathwayiUPA00074; UER00129.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligase (EC:6.3.3.1)
Alternative name(s):
AIR synthase
AIRS
Phosphoribosyl-aminoimidazole synthetase
Gene namesi
Name:purM
Ordered Locus Names:PSHAa1947
OrganismiPseudoalteromonas haloplanktis (strain TAC 125)
Taxonomic identifieri326442 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesPseudoalteromonadaceaePseudoalteromonas
ProteomesiUP000006843: Chromosome I

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 350350Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotation
PRO_0000258382Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi326442.PSHAa1947.

Structurei

3D structure databases

ProteinModelPortaliQ3IIQ2.
SMRiQ3IIQ2. Positions 7-345.

Family & Domainsi

Sequence similaritiesi

Belongs to the AIR synthase family.

Phylogenomic databases

eggNOGiCOG0150.
HOGENOMiHOG000229090.
KOiK01933.
OMAiEFEMYRT.
OrthoDBiEOG61CM1V.

Family and domain databases

Gene3Di3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPiMF_00741_B. AIRS_B.
InterProiIPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view]
PfamiPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view]
SUPFAMiSSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsiTIGR00878. purM. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3IIQ2-1 [UniParc]FASTAAdd to Basket

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MSEQKQSLSY KDAGVDIDAG NALVERIKGV VKKTRRPEVM GGIGGFGALC    50
EIPAGYKQPV LVAGTDGVGT KLRLAIDLKK HDTVGIDLVA MCVNDLIVQG 100
AEPLFFLDYY ATGKLDVDTA ADVVTGIGKG CEISGCALIG GETAEMPGMY 150
DGEDYDMAGF CTGVVEKSKI IDGTKVAAGD QLIALASSGP HSNGFSLIRK 200
VLEVSNADTS ADFEGKTLGE TLLEPTRIYV KPLLELFKHV DVHALSHITG 250
GGFWENIPRV LPASAKAVVK GDSWQWPPIF NWLQENGNIT THEMYRTFNC 300
GVGMVLVVPA DKLEQSLSML KDLGENAWHL GEIQDAAPGE EQVEIVGGAK 350
Length:350
Mass (Da):37,295
Last modified:November 8, 2005 - v1
Checksum:iB4F0FD0DD56F2296
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR954246 Genomic DNA. Translation: CAI87011.1.
RefSeqiYP_340454.1. NC_007481.1.

Genome annotation databases

EnsemblBacteriaiCAI87011; CAI87011; PSHAa1947.
GeneIDi3709940.
KEGGipha:PSHAa1947.
PATRICi32297491. VBIPseHal105694_1885.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR954246 Genomic DNA. Translation: CAI87011.1 .
RefSeqi YP_340454.1. NC_007481.1.

3D structure databases

ProteinModelPortali Q3IIQ2.
SMRi Q3IIQ2. Positions 7-345.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 326442.PSHAa1947.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAI87011 ; CAI87011 ; PSHAa1947 .
GeneIDi 3709940.
KEGGi pha:PSHAa1947.
PATRICi 32297491. VBIPseHal105694_1885.

Phylogenomic databases

eggNOGi COG0150.
HOGENOMi HOG000229090.
KOi K01933.
OMAi EFEMYRT.
OrthoDBi EOG61CM1V.

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00129 .
BioCyci PHAL326442:GJIU-1996-MONOMER.

Family and domain databases

Gene3Di 3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPi MF_00741_B. AIRS_B.
InterProi IPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view ]
Pfami PF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view ]
SUPFAMi SSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsi TIGR00878. purM. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TAC 125.

Entry informationi

Entry nameiPUR5_PSEHT
AccessioniPrimary (citable) accession number: Q3IIQ2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: November 8, 2005
Last modified: May 14, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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