Q3IHI4 (SYR_PSEHT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Arginine--tRNA ligase
EC=6.1.1.19

Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS

Gene names

Name:	argS
Ordered Locus Names:	PSHAa0656

Organism

Pseudoalteromonas haloplanktis (strain TAC 125) [Complete proteome] [HAMAP]

Taxonomic identifier

326442 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Pseudoalteromonadaceae › Pseudoalteromonas › Pseudoalteromonas haloplanktis

Protein attributes

Sequence length	580 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123
Subunit structure	Monomer By similarity. HAMAP-Rule MF_00123
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00123.
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	arginyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP arginine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 580	580	Arginine--tRNA ligase HAMAP-Rule MF_00123		PRO_0000242068
Regions
	Motif	123 – 133	11	"HIGH" region HAMAP-Rule MF_00123

Sequences

	Sequence		Length	Mass (Da)
	Q3IHI4 [UniParc]. Last modified November 8, 2005. Version 1. Checksum: A231842294783038	FASTA	580	64,218
	10 20 30 40 50 60 MNIRTILVEK AIAAMTTVGL PADTNPAVTQ STRPQFGDYQ INAAMGAAKK MKSNPRELAQ 70 80 90 100 110 120 KIIDNLDVSD IAEKTEIAGP GFINIHLKPE FLAQSVKAAN SDAKLAVNEH ANPQKVVVDY 130 140 150 160 170 180 SSPNLAKEMH VGHLRSTIIG DAIVRALEFR GDSVVRQNHM GDWGTQFGML IAHLEDQISQ 190 200 210 220 230 240 GVDLDTVALA DLETFYRDAK KRFDDEEGFA DKARNYVVKL QGGDAHCEKL WKLFIATSVK 250 260 270 280 290 300 HSEEVYKRLN VTLTQADIMA ESAYNAELND IISLLKDKNI AVESQGAQVV FLDELANKDG 310 320 330 340 350 360 EPSAFIVQKS GGGFLYATTD LAACDYRSNK LGADRILIFV DARQSLHFNQ VELTARKAGF 370 380 390 400 410 420 LRDETSYEFC PFGTMMGADN KPFKTRTGGT VKLADLLEES INRAAIKLAE RESDLSEQER 430 440 450 460 470 480 SEIARKVGIG AVKYADLSKH RTSDYIFNWD SMLSFEGATA PYLQYAYTRI RSIFRKSGVD 490 500 510 520 530 540 AATLNSNVTI VEPQEKALAL KLLQLEEVLD LMITEATPHV LCGYLYELAS LYMTFYEACP 550 560 570 580 VLKEGVEPNV RDSRLVLCNL VSKTLETGLD LLGIEVMEQM

References

[1]

"Coping with cold: the genome of the versatile marine Antarctica bacterium Pseudoalteromonas haloplanktis TAC125." Medigue C., Krin E., Pascal G., Barbe V., Bernsel A., Bertin P.N., Cheung F., Cruveiller S., D'Amico S., Duilio A., Fang G., Feller G., Ho C., Mangenot S., Marino G., Nilsson J., Parrilli E., Rocha E.P.C. , Rouy Z., Sekowska A., Tutino M.L., Vallenet D., von Heijne G., Danchin A. Genome Res. 15:1325-1335(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TAC 125.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR954246 Genomic DNA. Translation: CAI85741.1.
RefSeq	YP_339184.1. NC_007481.1.
3D structure databases
ProteinModelPortal	Q3IHI4.
ModBase	Search...
Protein-protein interaction databases
STRING	326442.PSHAa0656.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAI85741; CAI85741; PSHAa0656.
GeneID	3708785.
KEGG	pha:PSHAa0656.
PATRIC	32294841. VBIPseHal105694_0620.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0018.
HOGENOM	HOG000247212.
KO	K01887.
OMA	QGAKCVF.
ProtClustDB	PRK01611.
Enzyme and pathway databases
BioCyc	PHAL326442:GJIU-667-MONOMER.
Family and domain databases
Gene3D	3.30.1360.70. 1 hit. 3.40.50.620. 1 hit.
HAMAP	MF_00123. Arg_tRNA_synth.
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-ligase_Ia. IPR015945. Arg-tRNA-synth_Ia_core. IPR005148. Arg-tRNA-synth_N. IPR008909. DALR_anticod-bd. IPR014729. Rossmann-like_a/b/a_fold. IPR009080. tRNAsynth_1a_anticodon-bd. [Graphical view]
PANTHER	PTHR11956. PTHR11956. 1 hit.
Pfam	PF03485. Arg_tRNA_synt_N. 1 hit. PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 1 hit. [Graphical view]
PRINTS	PR01038. TRNASYNTHARG.
SMART	SM01016. Arg_tRNA_synt_N. 1 hit. SM00836. DALR_1. 1 hit. [Graphical view]
SUPFAM	SSF55190. Arg-tRNA-synth_Ic_N. 1 hit. SSF47323. tRNAsyn_1a_bind. 1 hit.
TIGRFAMs	TIGR00456. argS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYR_PSEHT

Accession

Primary (citable) accession number: Q3IHI4

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
Last sequence update:	November 8, 2005
Last modified:	May 1, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program