Q3IFR4 (Q3IFR4_PSEHT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphoribosylaminoimidazole-succinocarboxamide synthase HAMAP MF_00137
EC=6.3.2.6 HAMAP MF_00137

Alternative name(s):
SAICAR synthetase HAMAP MF_00137

Gene names

Name:	purC HAMAP MF_00137 EMBL CAI85551.1
Ordered Locus Names:	PSHAa0454

Organism

Pseudoalteromonas haloplanktis (strain TAC 125) [Complete proteome] [HAMAP]

Taxonomic identifier

326442 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Pseudoalteromonadaceae › Pseudoalteromonas

Protein attributes

Sequence length	367 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate. HAMAP MF_00137 SAAS SAAS001636
Pathway	Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2. HAMAP MF_00137 SAAS SAAS001636
Sequence similarities	Belongs to the SAICAR synthetase family. HAMAP MF_00137 RuleBase RU004193

Ontologies

Keywords
Biological process	Purine biosynthesis HAMAP MF_00137 SAAS SAAS001636
Ligand	ATP-binding HAMAP MF_00137 SAAS SAAS001636 Nucleotide-binding
Molecular function	Ligase HAMAP MF_00137 SAAS SAAS001636 EMBL CAI85551.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	purine nucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoribosylaminoimidazolesuccinocarboxamide synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q3IFR4 [UniParc]. Last modified November 8, 2005. Version 1. Checksum: 15680279EBB5DD97	FASTA	367	40,728
	10 20 30 40 50 60 MTSYKVLDVN DDLPIRTKGD VHSGKVRSVY WLTDADSKRL ISEKGYKVPA DTELAIMVIS 70 80 90 100 110 120 DRISAFDCIW QGENGLNGVP GKGIALNSVA AHWFKLFDEA GLAGNHIVDI PHPYVWIVRK 130 140 150 160 170 180 ASTVKVEAIA RQYITGSMWR DYAKGVRDFC GINLPEGLTA NQKLDKVLIT PSTKGIITGV 190 200 210 220 230 240 ADIPPVDDVN ITRSNITNNL SVFNFRAADD VAQYEKLLVE GFELISGELA KLGQIFVDTK 250 260 270 280 290 300 FEFGYVEDIN GAEQLIYIDE VGTPDSSRIW DEASYKDGKI VENSKEGFRQ LLINNVPESD 310 320 330 340 350 360 VLLNKDRMDE REQLAKDYIL PESVMLEVSN TYVGIASKIV GKEIVIPADP RQEVIAILDA DYGLIIK

References

[1]

"Coping with cold: the genome of the versatile marine Antarctica bacterium Pseudoalteromonas haloplanktis TAC125." Medigue C., Krin E., Pascal G., Barbe V., Bernsel A., Bertin P.N., Cheung F., Cruveiller S., D'Amico S., Duilio A., Fang G., Feller G., Ho C., Mangenot S., Marino G., Nilsson J., Parrilli E., Rocha E.P.C. , Rouy Z., Sekowska A., Tutino M.L., Vallenet D., von Heijne G., Danchin A. Genome Res. 15:1325-1335(2005) [PubMed: 16169927] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR954246 Genomic DNA. Translation: CAI85551.1.
RefSeq	YP_338994.1. NC_007481.1.
3D structure databases
ProteinModelPortal	Q3IFR4.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3IFR4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3709933.
GenomeReviews	Gene locus PSHAa0454 in contig CR954246_GR.
KEGG	pha:PSHAa0454.
NMPDR	fig|326442.4.peg.437.
PATRIC	32294429. VBIPseHal105694_0431.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0152.
HOGENOM	HBG555040.
OMA	SSRIWDG.
PhylomeDB	Q3IFR4.
ProtClustDB	PRK13960.
Enzyme and pathway databases
BioCyc	PHAL326442:PSHAA0454-MONOMER.
Family and domain databases
HAMAP	MF_00137. SAICAR_synth. [Tree]
InterPro	IPR013816. ATP_grasp_subdomain_2. IPR014106. PurC_vibrio. IPR001636. SAICAR_synth. [Graphical view]
Gene3D	G3DSA:3.30.470.20. ATP_grasp_subdomain_2. 1 hit.
KO	K01923.
PANTHER	PTHR11609. SAICAR_synt. 1 hit.
Pfam	PF01259. SAICAR_synt. 1 hit. [Graphical view]
TIGRFAMs	TIGR02735. PurC_vibrio. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q3IFR4_PSEHT

Accession

Primary (citable) accession number: Q3IFR4

Entry history

Integrated into UniProtKB/TrEMBL:	November 8, 2005
Last sequence update:	November 8, 2005
Last modified:	December 14, 2011
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)