Reviewed, UniProtKB/Swiss-Prot Q3IFQ5 (F16A1_PSEHT)

Names and origin

Protein names

Recommended name:
    Fructose-1,6-bisphosphatase class 1 1
      Short name=FBPase class 1 1
    EC=3.1.3.11
Alternative name(s):
    D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 1

Gene names

Name:	fbp1
Ordered Locus Names:	PSHAa0463

Organism

Pseudoalteromonas haloplanktis (strain TAC 125) [Complete proteome] [HAMAP]

Taxonomic identifier

326442 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Pseudoalteromonadaceae › Pseudoalteromonas

Protein attributes

Sequence length	322 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. HAMAP MF_01855
Cofactor	Binds 2 magnesium ions per subunit By similarity. HAMAP MF_01855
Pathway	Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_01855
Subunit structure	Homotetramer By similarity. HAMAP MF_01855
Subcellular location	Cytoplasm Potential HAMAP MF_01855.
Sequence similarities	Belongs to the FBPase class 1 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism
Cellular component	Cytoplasm
Ligand	Magnesium Metal-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	fructose 1,6-bisphosphate 1-phosphatase activity Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 322	322	Fructose-1,6-bisphosphatase class 1 1 HAMAP MF_01855		PRO_0000364637
Regions
	Region	106 – 109	4	Substrate binding By similarity
Sites
	Metal binding	84	1	Magnesium 1 By similarity
	Metal binding	103	1	Magnesium 1 By similarity
	Metal binding	103	1	Magnesium 2 By similarity
	Metal binding	105	1	Magnesium 1; via carbonyl oxygen By similarity
	Metal binding	106	1	Magnesium 2 By similarity
	Metal binding	270	1	Magnesium 2 By similarity
	Binding site	198	1	Substrate By similarity
	Binding site	264	1	Substrate By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q3IFQ5-1 [UniParc]. Last modified November 8, 2005. Version 1. Checksum: 9E4689C2E3350C29	FASTA	322	35,147
	10 20 30 40 50 60 MRRLPPVLLE DGCPRELISL IRTILAACKE ISFRVGQGEL SGVLGSTLDE NIQGETQKKL 70 80 90 100 110 120 DVLTNQLLKD ILLESGYVKA IASEEEDYTV AGNPDAEYIV AFDPLDGSSN TDINSLVGTI 130 140 150 160 170 180 FSVMKAPEGA DPADQSIFMQ PGINQVAAGY VLYGPSTILA LTTGKGTRFF TLDKTHGTFL 190 200 210 220 230 240 LTQDFAKIPA DTNEYAINAS NQRHWQPAMQ NYINDLVAGD TGPRARNFNM RWIAAMVGDV 250 260 270 280 290 300 HRVLSRGGLF TYPTDTKNPS QPNKLRLLYE ANPMAMLVEQ AGGIASTGTE RIMDIQPNAI 310 320 HQRVAVILGS KNEVETCLGY HK

References

[1]

"Coping with cold: the genome of the versatile marine Antarctica bacterium Pseudoalteromonas haloplanktis TAC125." Medigue C., Krin E., Pascal G., Barbe V., Bernsel A., Bertin P.N., Cheung F., Cruveiller S., D'Amico S., Duilio A., Fang G., Feller G., Ho C., Mangenot S., Marino G., Nilsson J., Parrilli E., Rocha E.P.C. , Rouy Z., Sekowska A., Tutino M.L., Vallenet D., von Heijne G., Danchin A. Genome Res. 15:1325-1335(2005) [PubMed: 16169927] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR954246 Genomic DNA. Translation: CAI85560.1.
RefSeq	YP_339003.1.
3D structure databases
HSSP	HSSP built from PDB template 2GQ1 based on UniProtKB P0A993.
SMR	Q3IFQ5. Positions 13-321.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3IFQ5.
Genome annotation databases
GeneID	3709325.
GenomeReviews	Gene locus PSHAa0463 in contig CR954246_GR.
KEGG	pha:PSHAa0463.
NMPDR	fig|326442.4.peg.446.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0158.
HOGENOM	HBG731261.
OMA	CEETSAL.
PhylomeDB	Q3IFQ5.
Enzyme and pathway databases
BioCyc	PHAL326442:PSHAA0463-MONOMER.
Family and domain databases
HAMAP	MF_01855. FBPase_class1. [Tree]
InterPro	IPR000146. Fructose_bisphosphatase. [Graphical view]
PANTHER	PTHR11556. In_FB_phphtase. 1 hit.
Pfam	PF00316. FBPase. 1 hit. [Graphical view]
PRINTS	PR00115. F16BPHPHTASE.
PROSITE	PS00124. FBPASE. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

F16A1_PSEHT

Accession

Primary (citable) accession number: Q3IFQ5

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 3, 2009
Last sequence update:	November 8, 2005
Last modified:	January 19, 2010
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)