Reviewed, UniProtKB/Swiss-Prot Q3IFP4 (SYK3_PSEHT)

Names and origin

Protein names

Recommended name:
    Putative lysyl-tRNA synthetase
    EC=6.1.1.6
Alternative name(s):
    Lysine--tRNA ligase
      Short name=LysRS
    GX

Gene names

Name:	poxA
Ordered Locus Names:	PSHAa0475

Organism

Pseudoalteromonas haloplanktis (strain TAC 125) [Complete proteome] [HAMAP]

Taxonomic identifier

326442 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Pseudoalteromonadaceae › Pseudoalteromonas

Protein attributes

Sequence length	324 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Could be a lysyl-tRNA synthetase. HAMAP MF_00174
Catalytic activity	ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). HAMAP MF_00174
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lysyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP lysine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 324	324	Putative lysyl-tRNA synthetase HAMAP MF_00174		PRO_1000023628

Sequences

	Sequence		Length	Mass (Da)
	Q3IFP4-1 [UniParc]. Last modified November 8, 2005. Version 1. Checksum: 629881F0BC860BAF	FASTA	324	36,295
	10 20 30 40 50 60 MSVNLWAPSA SIATLKQRAV ILRSIREFFY ARNVMEVETP SLSGASVTDI HLVSFNTRFV 70 80 90 100 110 120 GPGHASGLEL YLQTSPEFAM KRLLAAGSGP IFQLCKAFRN EEAGSHHNPE FTMLEWYRPG 130 140 150 160 170 180 FDEFALMAEI DELMQLILDV APSERLTYQH AFEQVLGLDP LTASLEQLQQ LACEQGFADI 190 200 210 220 230 240 AKNETHRDTL LQLLFCMKVE PTIGQHKPCF VYHFPASQAA LAQICDHDSR VAGRFELYYK 250 260 270 280 290 300 NMELANGFNE LTNATEQAKR FNDDNEYRKQ NGLKQVPMDK HLIAALEHGL APCAGVALGI 310 320 DRLVMLATQK SNIKEVIAFD VTRA

References

[1]

"Coping with cold: the genome of the versatile marine Antarctica bacterium Pseudoalteromonas haloplanktis TAC125." Medigue C., Krin E., Pascal G., Barbe V., Bernsel A., Bertin P.N., Cheung F., Cruveiller S., D'Amico S., Duilio A., Fang G., Feller G., Ho C., Mangenot S., Marino G., Nilsson J., Parrilli E., Rocha E.P.C. , Rouy Z., Sekowska A., Tutino M.L., Vallenet D., von Heijne G., Danchin A. Genome Res. 15:1325-1335(2005) [PubMed: 16169927] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR954246 Genomic DNA. Translation: CAI85572.1.
RefSeq	YP_339015.1.
3D structure databases
SMR	Q3IFP4. Positions 8-323.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3IFP4.
Genome annotation databases
GeneID	3708719.
GenomeReviews	Gene locus PSHAa0475 in contig CR954246_GR.
KEGG	pha:PSHAa0475.
NMPDR	fig|326442.4.peg.458.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2269.
HOGENOM	HBG631383.
OMA	PGNEAHL.
PhylomeDB	Q3IFP4.
Enzyme and pathway databases
BioCyc	PHAL326442:PSHAA0475-MONOMER.
Family and domain databases
HAMAP	MF_00174. Put_Lys_tRNA_synth. [Tree]
InterPro	IPR004364. aa-tRNA-synt_II. IPR018150. aa-tRNA-synt_II-like. IPR006195. aa-tRNA-synth_II_cons-dom. IPR004525. Lys-tRNA-synth-rel. IPR018149. Lys-tRNA-synth_II_C. [Graphical view]
PANTHER	PTHR22594. aa-tRNA-synt_II. 1 hit.
Pfam	PF00152. tRNA-synt_2. 1 hit. [Graphical view]
PRINTS	PR00982. TRNASYNTHLYS.
TIGRFAMs	TIGR00462. genX. 1 hit.
PROSITE	PS50862. AA_TRNA_LIGASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYK3_PSEHT

Accession

Primary (citable) accession number: Q3IFP4

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	November 8, 2005
Last modified:	February 9, 2010
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)