plsB

Functionⁱ

Catalytic activityⁱ

Acyl-CoA + sn-glycerol 3-phosphate = CoA + 1-acyl-sn-glycerol 3-phosphate.UniRule annotation

Pathwayⁱ: CDP-diacylglycerol biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes CDP-diacylglycerol from sn-glycerol 3-phosphate.UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:

Glycerol-3-phosphate acyltransferase (plsB)
no protein annotated in this organism
Phosphatidate cytidylyltransferase (cdsA)

This subpathway is part of the pathway CDP-diacylglycerol biosynthesis, which is itself part of Phospholipid metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes CDP-diacylglycerol from sn-glycerol 3-phosphate, the pathway CDP-diacylglycerol biosynthesis and in Phospholipid metabolism.

GO - Molecular functionⁱ

glycerol-3-phosphate O-acyltransferase activity Source: UniProtKB-EC
sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity Source: UniProtKB-EC

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

CDP-diacylglycerol biosynthetic process Source: UniProtKB-UniPathway

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Acyltransferase, Transferase
Biological process	Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism

Enzyme and pathway databases

BioCycⁱ	PHAL326442:G1GI4-146-MONOMER.
UniPathwayⁱ	UPA00557; UER00612.

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Glycerol-3-phosphate acyltransferaseUniRule annotation (EC:2.3.1.15UniRule annotation) Short name: GPATUniRule annotation
Gene namesⁱ	Name:plsBUniRule annotation Ordered Locus Names:PSHAa0142
Organismⁱ	Pseudoalteromonas haloplanktis (strain TAC 125)
Taxonomic identifierⁱ	326442 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Pseudoalteromonadaceae › Pseudoalteromonas › Pseudoalteromonas haloplanktis
Proteomesⁱ	UP000006843 Componentⁱ: Chromosome I

Subcellular locationⁱ

Cell inner membrane
UniRule annotation
Manual assertion according to rulesⁱ
- HAMAP-Rule:MF_00393
; Peripheral membrane protein
UniRule annotation
Manual assertion according to rulesⁱ
- HAMAP-Rule:MF_00393
; Cytoplasmic side
UniRule annotation
Manual assertion according to rulesⁱ
- HAMAP-Rule:MF_00393

GO - Cellular componentⁱ

plasma membrane Source: UniProtKB-SubCell

View the complete GO annotation on QuickGO ...

Keywords - Cellular componentⁱ

Cell inner membrane, Cell membrane, Membrane

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_1000049446	1 – 812	Glycerol-3-phosphate acyltransferaseAdd BLAST		812

Proteomic databases

PRIDEⁱ	Q3IF27.

PRIDEⁱ

Q3IF27.

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	326442.PSHAa0142.

STRINGⁱ

326442.PSHAa0142.

Family & Domainsⁱ

Motif

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Motifⁱ	308 – 313	HXXXXD motif		6

Domainⁱ

The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.UniRule annotation

Sequence similaritiesⁱ

Belongs to the GPAT/DAPAT family.UniRule annotation

Phylogenomic databases

eggNOGⁱ	ENOG4105E55. Bacteria. COG2937. LUCA.
HOGENOMⁱ	HOG000218231.
KEGG Orthology (KO) More...KOⁱ	K00631.
OMAⁱ	EVIYVPC.
Database of Orthologous Groups More...OrthoDBⁱ	POG091H06BX.

Family and domain databases

HAMAPⁱ	MF_00393. Glyc3P_acyltrans. 1 hit.
InterProⁱ	View protein in InterPro IPR022284. GPAT/DHAPAT. IPR028354. GPAT_PlsB. IPR002123. Plipid/glycerol_acylTrfase.
PANTHERⁱ	PTHR12563. PTHR12563. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01553. Acyltransferase. 1 hit.
PIRSFⁱ	PIRSF500064. GPAT. 1 hit. PIRSF000437. GPAT_DHAPAT. 1 hit.
SMARTⁱ	View protein in SMART SM00563. PlsC. 1 hit.
TIGRFAMsⁱ	TIGR03703. plsB. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q3IF27-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MRIVNYCLNV LSAGVSRLLV RSKVLPEKPT EQYELNSKNP TFYIVRLNSR 
        60         70         80         90        100
FDLAALARVC KRHGLPDPRE QQVLGTQRLD RFIGIENPPP LIGDIAKPTN 
       110        120        130        140        150
ALAQGKQIID HLLSSGQKDV QVIPVTILWG RAPGKEKPGL STLITHSLTP 
       160        170        180        190        200
SWFRKLFVVL FSGRDNFIRF SQPLDLSLLV DEKADVNELP QKLLRVARVH 
       210        220        230        240        250
FRRQKLAATG PKMPSREQLF NSLLASPTIK KAIQDEAKAK NISQAQARQN 
       260        270        280        290        300
AVKLLNEIAA NYSEAMIRVA ERFLTWLWNK LYNGIDIKYT EQIHELTNKG 
       310        320        330        340        350
HEIIYMPCHR SHMDYLLLTY AIYHQGLVPP HIAAGINLNF FPAGGIFRRS 
       360        370        380        390        400
GAFFIRRSFA GNKLYSAVFK EYLSQLFIKG YSVKFYTEGG RSRTGRLLPP 
       410        420        430        440        450
KTGMLAMTMQ AMLRGIDRPI SIVPVYIGYE HVMEINTYLK ELAGNDKKGE 
       460        470        480        490        500
SIFGIFKAIK NLKNYGRGYL NFGDPISINQ YLNDNQPNWR DDIHPTDVQK 
       510        520        530        540        550
PQWLGPQVAN LADQVMVKIN NAAALNAVNL LAMILLVNDK HALSKPKLLA 
       560        570        580        590        600
QLDFYLRLQR DASYSNKVTA PEETPEQLLT HALKLNKFDV ISDEFGEIIA 
       610        620        630        640        650
INDKEKTLFN YYRNNILHLF AVPSLIALHL FREKTTTVSK CQQLVAAFYP 
       660        670        680        690        700
LFAKEWYLRE LDEDYITRIL ANFVDQNLIE LDGDNIHITN TNDCLAKLDM 
       710        720        730        740        750
LGKALNFTLQ RYAIVIGFIQ TSNGIEKAEL ERESQVLAQR LGTLHGIKTP 
       760        770        780        790        800
EFFDKKVLVS FIDNLRAQSL ITDGDAGLIG SVQLCETYMH LKALLPARVW 
       810 
QSISDIVQGQ CK

Length:812

Mass (Da):92,076

Last modified:November 8, 2005 - v1

Checksum:ⁱ1751179DED26D381

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CR954246 Genomic DNA. Translation: CAI85246.1.
NCBI Reference Sequences More...RefSeqⁱ	WP_011326864.1. NC_007481.1.

Genome annotation databases

EnsemblBacteriaⁱ	CAI85246; CAI85246; PSHAa0142.
KEGGⁱ	pha:PSHAa0142.
PATRICⁱ	fig\|326442.8.peg.136.

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q3IF27	A0A2K4XDE0 A0A1R4ITV3 A0A221IFM6 A0A0U2VDE6 A0A0W1KU22	Pseudoalteromonas carrageenovora IAM 12662 Pseudoalteromonas sp. JB197 Pseudoalteromonas nigrifaciens Pseudoalteromonas translucida KMM 520 Pseudoalteromonas sp. H103	812	UniRef90_Q3IF27	Cluster: Glycerol-3-phosphate acyltransferase	6

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q3IF27	A0A0W1KU22 A0A1R4ITV3 A0A221IFM6 A0A0U2VDE6 A0A2K4XDE0 A4CE40 A0A166UWY8 UPI0007B03F04 A0A167CZU6 UPI0007BBF8A0 +86	Pseudoalteromonas sp. H103 Pseudoalteromonas sp. JB197 Pseudoalteromonas nigrifaciens Pseudoalteromonas translucida KMM 520 Pseudoalteromonas carrageenovora IAM 12662 Pseudoalteromonas tunicata D2 Pseudoalteromonas luteoviolacea DSM 6061 Pseudoalteromonas luteoviolacea Pseudoalteromonas luteoviolacea NCIMB 1942 Pseudoalteromonas luteoviolacea S4060-1 And more	812	UniRef50_Q3IF27	Cluster: Glycerol-3-phosphate acyltransferase	97

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CR954246 Genomic DNA. Translation: CAI85246.1.
NCBI Reference Sequences More...RefSeqⁱ	WP_011326864.1. NC_007481.1.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	326442.PSHAa0142.

STRINGⁱ

326442.PSHAa0142.

Proteomic databases

PRIDEⁱ	Q3IF27.

PRIDEⁱ

Q3IF27.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	CAI85246; CAI85246; PSHAa0142.
KEGGⁱ	pha:PSHAa0142.
PATRICⁱ	fig\|326442.8.peg.136.

Phylogenomic databases

eggNOGⁱ	ENOG4105E55. Bacteria. COG2937. LUCA.
HOGENOMⁱ	HOG000218231.
KEGG Orthology (KO) More...KOⁱ	K00631.
OMAⁱ	EVIYVPC.
Database of Orthologous Groups More...OrthoDBⁱ	POG091H06BX.

Enzyme and pathway databases

UniPathwayⁱ	UPA00557; UER00612.
BioCycⁱ	PHAL326442:G1GI4-146-MONOMER.

Family and domain databases

HAMAPⁱ	MF_00393. Glyc3P_acyltrans. 1 hit.
InterProⁱ	View protein in InterPro IPR022284. GPAT/DHAPAT. IPR028354. GPAT_PlsB. IPR002123. Plipid/glycerol_acylTrfase.
PANTHERⁱ	PTHR12563. PTHR12563. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01553. Acyltransferase. 1 hit.
PIRSFⁱ	PIRSF500064. GPAT. 1 hit. PIRSF000437. GPAT_DHAPAT. 1 hit.
SMARTⁱ	View protein in SMART SM00563. PlsC. 1 hit.
TIGRFAMsⁱ	TIGR03703. plsB. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	PLSB_PSEHT
Accessionⁱ	Q3IF27Primary (citable) accession number: Q3IF27
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
	Last sequence update:	November 8, 2005
	Last modified:	February 28, 2018
	This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Prokaryotic Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q3IF27 (PLSB_PSEHT)

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Glycerol-3-phosphate acyltransferase

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">‘Function’</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: CDP-diacylglycerol biosynthesis

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Motif

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

Pathwayⁱ: CDP-diacylglycerol biosynthesis

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Interactionⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ