UniProtKB - Q3IF27 (PLSB_PSEHT)
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Protein
Glycerol-3-phosphate acyltransferase
Gene
plsB
Organism
Pseudoalteromonas haloplanktis (strain TAC 125)
Status
Functioni
Catalytic activityi
Acyl-CoA + sn-glycerol 3-phosphate = CoA + 1-acyl-sn-glycerol 3-phosphate.UniRule annotation
: CDP-diacylglycerol biosynthesis Pathwayi
This protein is involved in step 1 of the subpathway that synthesizes CDP-diacylglycerol from sn-glycerol 3-phosphate.UniRule annotationProteins known to be involved in the 3 steps of the subpathway in this organism are:
- Glycerol-3-phosphate acyltransferase (plsB)
- no protein annotated in this organism
- Phosphatidate cytidylyltransferase (cdsA)
View all proteins of this organism that are known to be involved in the subpathway that synthesizes CDP-diacylglycerol from sn-glycerol 3-phosphate, the pathway CDP-diacylglycerol biosynthesis and in Phospholipid metabolism.
GO - Molecular functioni
- glycerol-3-phosphate O-acyltransferase activity Source: UniProtKB-EC
- sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity Source: UniProtKB-EC
GO - Biological processi
- CDP-diacylglycerol biosynthetic process Source: UniProtKB-UniPathway
Keywordsi
Molecular function | Acyltransferase, Transferase |
Biological process | Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism |
Enzyme and pathway databases
BioCyci | PHAL326442:G1GI4-146-MONOMER. |
UniPathwayi | UPA00557; UER00612. |
Names & Taxonomyi
Protein namesi | Recommended name: Glycerol-3-phosphate acyltransferaseUniRule annotation (EC:2.3.1.15UniRule annotation)Short name: GPATUniRule annotation |
Gene namesi | Name:plsBUniRule annotation Ordered Locus Names:PSHAa0142 |
Organismi | Pseudoalteromonas haloplanktis (strain TAC 125) |
Taxonomic identifieri | 326442 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Pseudoalteromonadaceae › Pseudoalteromonas › |
Proteomesi |
|
Subcellular locationi
- Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation; Cytoplasmic side UniRule annotation
GO - Cellular componenti
- plasma membrane Source: UniProtKB-SubCell
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_1000049446 | 1 – 812 | Glycerol-3-phosphate acyltransferaseAdd BLAST | 812 |
Proteomic databases
PRIDEi | Q3IF27. |
Family & Domainsi
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 308 – 313 | HXXXXD motif | 6 |
Domaini
The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.UniRule annotation
Sequence similaritiesi
Belongs to the GPAT/DAPAT family.UniRule annotation
Phylogenomic databases
eggNOGi | ENOG4105E55. Bacteria. COG2937. LUCA. |
HOGENOMi | HOG000218231. |
KOi | K00631. |
OMAi | EVIYVPC. |
OrthoDBi | POG091H06BX. |
Family and domain databases
HAMAPi | MF_00393. Glyc3P_acyltrans. 1 hit. |
InterProi | View protein in InterPro IPR022284. GPAT/DHAPAT. IPR028354. GPAT_PlsB. IPR002123. Plipid/glycerol_acylTrfase. |
PANTHERi | PTHR12563. PTHR12563. 1 hit. |
Pfami | View protein in Pfam PF01553. Acyltransferase. 1 hit. |
PIRSFi | PIRSF500064. GPAT. 1 hit. PIRSF000437. GPAT_DHAPAT. 1 hit. |
SMARTi | View protein in SMART SM00563. PlsC. 1 hit. |
TIGRFAMsi | TIGR03703. plsB. 1 hit. |
i Sequence
Sequence statusi: Complete.
Q3IF27-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRIVNYCLNV LSAGVSRLLV RSKVLPEKPT EQYELNSKNP TFYIVRLNSR
60 70 80 90 100
FDLAALARVC KRHGLPDPRE QQVLGTQRLD RFIGIENPPP LIGDIAKPTN
110 120 130 140 150
ALAQGKQIID HLLSSGQKDV QVIPVTILWG RAPGKEKPGL STLITHSLTP
160 170 180 190 200
SWFRKLFVVL FSGRDNFIRF SQPLDLSLLV DEKADVNELP QKLLRVARVH
210 220 230 240 250
FRRQKLAATG PKMPSREQLF NSLLASPTIK KAIQDEAKAK NISQAQARQN
260 270 280 290 300
AVKLLNEIAA NYSEAMIRVA ERFLTWLWNK LYNGIDIKYT EQIHELTNKG
310 320 330 340 350
HEIIYMPCHR SHMDYLLLTY AIYHQGLVPP HIAAGINLNF FPAGGIFRRS
360 370 380 390 400
GAFFIRRSFA GNKLYSAVFK EYLSQLFIKG YSVKFYTEGG RSRTGRLLPP
410 420 430 440 450
KTGMLAMTMQ AMLRGIDRPI SIVPVYIGYE HVMEINTYLK ELAGNDKKGE
460 470 480 490 500
SIFGIFKAIK NLKNYGRGYL NFGDPISINQ YLNDNQPNWR DDIHPTDVQK
510 520 530 540 550
PQWLGPQVAN LADQVMVKIN NAAALNAVNL LAMILLVNDK HALSKPKLLA
560 570 580 590 600
QLDFYLRLQR DASYSNKVTA PEETPEQLLT HALKLNKFDV ISDEFGEIIA
610 620 630 640 650
INDKEKTLFN YYRNNILHLF AVPSLIALHL FREKTTTVSK CQQLVAAFYP
660 670 680 690 700
LFAKEWYLRE LDEDYITRIL ANFVDQNLIE LDGDNIHITN TNDCLAKLDM
710 720 730 740 750
LGKALNFTLQ RYAIVIGFIQ TSNGIEKAEL ERESQVLAQR LGTLHGIKTP
760 770 780 790 800
EFFDKKVLVS FIDNLRAQSL ITDGDAGLIG SVQLCETYMH LKALLPARVW
810
QSISDIVQGQ CK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CR954246 Genomic DNA. Translation: CAI85246.1. |
RefSeqi | WP_011326864.1. NC_007481.1. |
Genome annotation databases
EnsemblBacteriai | CAI85246; CAI85246; PSHAa0142. |
KEGGi | pha:PSHAa0142. |
PATRICi | fig|326442.8.peg.136. |
Similar proteinsi
Entry informationi
Entry namei | PLSB_PSEHT | |
Accessioni | Q3IF27Primary (citable) accession number: Q3IF27 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 15, 2008 |
Last sequence update: | November 8, 2005 | |
Last modified: | February 28, 2018 | |
This is version 76 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |