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Q3IDD5

- GPPA_PSEHT

UniProt

Q3IDD5 - GPPA_PSEHT

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Protein
Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase
Gene
gppA, PSHAa0115
Organism
Pseudoalteromonas haloplanktis (strain TAC 125)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the "stringent response", an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities By similarity.UniRule annotation

Catalytic activityi

Guanosine 5'-triphosphate,3'-diphosphate + H2O = guanosine 3',5'-bis(diphosphate) + phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity Source: UniProtKB-EC

GO - Biological processi

  1. guanosine pentaphosphate catabolic process Source: InterPro
  2. guanosine tetraphosphate biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciPHAL326442:GJIU-117-MONOMER.
UniPathwayiUPA00908; UER00884.

Names & Taxonomyi

Protein namesi
Recommended name:
Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase (EC:3.6.1.40)
Alternative name(s):
Guanosine pentaphosphate phosphohydrolase
pppGpp-5'-phosphohydrolase
Gene namesi
Name:gppA
Ordered Locus Names:PSHAa0115
OrganismiPseudoalteromonas haloplanktis (strain TAC 125)
Taxonomic identifieri326442 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesPseudoalteromonadaceaePseudoalteromonas
ProteomesiUP000006843: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 497497Guanosine-5'-triphosphate,3'-diphosphate pyrophosphataseUniRule annotation
PRO_0000194285Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi326442.PSHAa0115.

Structurei

3D structure databases

ProteinModelPortaliQ3IDD5.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0248.
HOGENOMiHOG000258672.
KOiK01524.
OrthoDBiEOG6M6JN6.

Family and domain databases

HAMAPiMF_01550. GppA.
InterProiIPR023709. Guo-5TP_3DP_PyrP.
IPR003695. Ppx_GppA.
[Graphical view]
PfamiPF02541. Ppx-GppA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3IDD5-1 [UniParc]FASTAAdd to Basket

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MGQLKPQKNV YAVIDLGSNS FHMLIAKSIA GGLQTIGRVK RKVRLAAGLD    50
IDNVLSSEAM HRGWECLALF AERLQDIPKQ NITIVATATL RLASNADVFK 100
AQAEKILGHK VNVISGELEA RTIYKGVAHT SSCTGSQLVI DIGGASTEVI 150
IGKNFDALLY KSLNIGCVTY LERYFKDCKL SNANFNTAIK AARTVIDEIA 200
SEYKVKGWQI ASGASGTVQA IQEIMIAQNL DELLTLEKLY TIKKQSIAYK 250
TIAALDLPGL SEDRRLVFVS GLAILIALFE SLEIEKMGLA GGALREGVLY 300
SMLPELHNSD IRKRTIDGFI DRYHVDQKQA SRVASLVLNL ASEVNESWPI 350
KALNGLPLLT AVAQLHEIGL LIEYKQYHKH SAYILKNTEM PGFSQSEHKV 400
IVAVAKGHRS DLQKGYFDSL GANSVLAQYL VRLIRIAVIL CMRRQDDVLP 450
EFAITVKDDV LNLQFENDWL KNHPLMASEL QQESKQQAKL GWKLIVN 497
Length:497
Mass (Da):54,968
Last modified:December 20, 2005 - v2
Checksum:iC7E1CC2B2FEB8A26
GO

Sequence cautioni

The sequence CAI85224.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR954246 Genomic DNA. Translation: CAI85224.1. Different initiation.
RefSeqiYP_338667.2. NC_007481.1.

Genome annotation databases

EnsemblBacteriaiCAI85224; CAI85224; PSHAa0115.
GeneIDi3707992.
KEGGipha:PSHAa0115.
PATRICi32293765. VBIPseHal105694_0114.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR954246 Genomic DNA. Translation: CAI85224.1 . Different initiation.
RefSeqi YP_338667.2. NC_007481.1.

3D structure databases

ProteinModelPortali Q3IDD5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 326442.PSHAa0115.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAI85224 ; CAI85224 ; PSHAa0115 .
GeneIDi 3707992.
KEGGi pha:PSHAa0115.
PATRICi 32293765. VBIPseHal105694_0114.

Phylogenomic databases

eggNOGi COG0248.
HOGENOMi HOG000258672.
KOi K01524.
OrthoDBi EOG6M6JN6.

Enzyme and pathway databases

UniPathwayi UPA00908 ; UER00884 .
BioCyci PHAL326442:GJIU-117-MONOMER.

Family and domain databases

HAMAPi MF_01550. GppA.
InterProi IPR023709. Guo-5TP_3DP_PyrP.
IPR003695. Ppx_GppA.
[Graphical view ]
Pfami PF02541. Ppx-GppA. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TAC 125.

Entry informationi

Entry nameiGPPA_PSEHT
AccessioniPrimary (citable) accession number: Q3IDD5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 20, 2005
Last modified: May 14, 2014
This is version 51 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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