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Q3IDA4

- UPPP2_PSEHT

UniProt

Q3IDA4 - UPPP2_PSEHT

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Protein

Undecaprenyl-diphosphatase 2

Gene
uppP2, PSHAb0269
Organism
Pseudoalteromonas haloplanktis (strain TAC 125)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity.UniRule annotation

Catalytic activityi

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate.UniRule annotation

GO - Molecular functioni

  1. undecaprenyl-diphosphatase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. dephosphorylation Source: InterPro
  2. peptidoglycan biosynthetic process Source: UniProtKB-KW
  3. regulation of cell shape Source: UniProtKB-KW
  4. response to antibiotic Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Antibiotic resistance, Cell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

Enzyme and pathway databases

BioCyciPHAL326442:GJIU-3334-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Undecaprenyl-diphosphatase 2 (EC:3.6.1.27)
Alternative name(s):
Bacitracin resistance protein 2
Undecaprenyl pyrophosphate phosphatase 2
Gene namesi
Name:uppP2
Ordered Locus Names:PSHAb0269
OrganismiPseudoalteromonas haloplanktis (strain TAC 125)
Taxonomic identifieri326442 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesPseudoalteromonadaceaePseudoalteromonas
ProteomesiUP000006843: Chromosome II

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei1 – 2121Helical; Reviewed predictionAdd
BLAST
Transmembranei38 – 5821Helical; Reviewed predictionAdd
BLAST
Transmembranei70 – 9021Helical; Reviewed predictionAdd
BLAST
Transmembranei97 – 11721Helical; Reviewed predictionAdd
BLAST
Transmembranei134 – 15421Helical; Reviewed predictionAdd
BLAST
Transmembranei175 – 19521Helical; Reviewed predictionAdd
BLAST
Transmembranei208 – 22821Helical; Reviewed predictionAdd
BLAST
Transmembranei236 – 25621Helical; Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 256256Undecaprenyl-diphosphatase 2UniRule annotationPRO_0000227628Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi326442.PSHAb0269.

Family & Domainsi

Sequence similaritiesi

Belongs to the UppP family.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1968.
HOGENOMiHOG000218356.
KOiK06153.
OMAiWRKISSS.
OrthoDBiEOG6QP13M.

Family and domain databases

HAMAPiMF_01006. Undec_diphosphatase.
InterProiIPR003824. UppP.
[Graphical view]
PfamiPF02673. BacA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3IDA4-1 [UniParc]FASTAAdd to Basket

« Hide

MDIFNAIILG IIEGITEFLP ISSTGHIIVA AQWLGIEATA TNQAFGVIIQ    50
LAAILAVLAN YKDKFTPKHL NLWIKVAIAF IPLGIIAFIF SDVIKALFNV 100
PVVGVMFIVG GVIFLLLERN YKEQNCTTTD VTQVTYKQAI WIGIAQVFAL 150
IPGTSRAGSS IVGAMLCGLN RKASAEFSFL LGLPVLAAAS GYDLLKHYDL 200
FTFDDLTALA VGFVTSFIVA YFTIKLFIRF LENFTFVSFG IYRIVFGVIL 250
LTIAYV 256
Length:256
Mass (Da):27,979
Last modified:November 8, 2005 - v1
Checksum:iCC732AC0024ECA59
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR954247 Genomic DNA. Translation: CAI89310.1.
RefSeqiWP_011329899.1. NC_007482.1.
YP_341756.1. NC_007482.1.

Genome annotation databases

EnsemblBacteriaiCAI89310; CAI89310; PSHAb0269.
GeneIDi3711227.
KEGGipha:PSHAb0269.
PATRICi32300150. VBIPseHal105694_3179.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR954247 Genomic DNA. Translation: CAI89310.1 .
RefSeqi WP_011329899.1. NC_007482.1.
YP_341756.1. NC_007482.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 326442.PSHAb0269.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAI89310 ; CAI89310 ; PSHAb0269 .
GeneIDi 3711227.
KEGGi pha:PSHAb0269.
PATRICi 32300150. VBIPseHal105694_3179.

Phylogenomic databases

eggNOGi COG1968.
HOGENOMi HOG000218356.
KOi K06153.
OMAi WRKISSS.
OrthoDBi EOG6QP13M.

Enzyme and pathway databases

BioCyci PHAL326442:GJIU-3334-MONOMER.

Family and domain databases

HAMAPi MF_01006. Undec_diphosphatase.
InterProi IPR003824. UppP.
[Graphical view ]
Pfami PF02673. BacA. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TAC 125.

Entry informationi

Entry nameiUPPP2_PSEHT
AccessioniPrimary (citable) accession number: Q3IDA4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: November 8, 2005
Last modified: September 3, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi