Reviewed, UniProtKB/Swiss-Prot Q3ICJ5 (F16A3_PSEHT)

Names and origin

Protein names

Recommended name:
    Fructose-1,6-bisphosphatase class 1 3
      Short name=FBPase class 1 3
    EC=3.1.3.11
Alternative name(s):
    D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 3

Gene names

Name:	fbp3
Ordered Locus Names:	PSHAb0549

Organism

Pseudoalteromonas haloplanktis (strain TAC 125) [Complete proteome] [HAMAP]

Taxonomic identifier

326442 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Pseudoalteromonadaceae › Pseudoalteromonas

Protein attributes

Sequence length	322 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. HAMAP MF_01855
Cofactor	Binds 2 magnesium ions per subunit By similarity.
Pathway	Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_01855
Subunit structure	Homotetramer By similarity.
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the FBPase class 1 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism
Cellular component	Cytoplasm
Ligand	Magnesium Metal-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	fructose 1,6-bisphosphate 1-phosphatase activity Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 322	322	Fructose-1,6-bisphosphatase class 1 3 HAMAP MF_01855		PRO_0000364639
Regions
	Region	106 – 109	4	Substrate binding By similarity
Sites
	Metal binding	84	1	Magnesium 1 By similarity
	Metal binding	103	1	Magnesium 1 By similarity
	Metal binding	103	1	Magnesium 2 By similarity
	Metal binding	105	1	Magnesium 1; via carbonyl oxygen By similarity
	Metal binding	106	1	Magnesium 2 By similarity
	Metal binding	268	1	Magnesium 2 By similarity
	Binding site	198	1	Substrate By similarity
	Binding site	262	1	Substrate By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q3ICJ5-1 [UniParc]. Last modified November 8, 2005. Version 1. Checksum: 27F830B67C715F1C	FASTA	322	35,429
	10 20 30 40 50 60 MKNLYTQLEQ DNVPKTLTLL LQSIVGACTE IATRINHGAL SDVLGSLPDH NVQGEVQKKL 70 80 90 100 110 120 DVIANNILIE SLKKNKQVRA VASEEVEDII LCNSFGKYLI CFDPLDGSSN TDVNGSLGTI 130 140 150 160 170 180 FSITSASAAQ TEVSEEDFFS TGRSIIAAGY VLYGPSLMLA LSTGSGTHIY TLDPSNNNFM 190 200 210 220 230 240 LTHPNLNIPE DTNEFSFNLS NQFKWPENVQ KYIVDLQLGT DGIRKKNFNM RWLGAMVGDM 250 260 270 280 290 300 HRILCKGGIF GYPEEKNFKY GKLRLLYEAN PIAFLVEQAN GLASNGTTSI LDTVPSSIHQ 310 320 RIPVFIGSKN EVLLIEKYAL GK

References

[1]

"Coping with cold: the genome of the versatile marine Antarctica bacterium Pseudoalteromonas haloplanktis TAC125." Medigue C., Krin E., Pascal G., Barbe V., Bernsel A., Bertin P.N., Cheung F., Cruveiller S., D'Amico S., Duilio A., Fang G., Feller G., Ho C., Mangenot S., Marino G., Nilsson J., Parrilli E., Rocha E.P.C. , Rouy Z., Sekowska A., Tutino M.L., Vallenet D., von Heijne G., Danchin A. Genome Res. 15:1325-1335(2005) [PubMed: 16169927] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CR954247 Genomic DNA. Translation: CAI89585.1.
RefSeq	YP_342031.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q3ICJ5.
Genome annotation databases
GeneID	3711439.
GenomeReviews	Gene locus PSHAb0549 in contig CR954247_GR.
KEGG	pha:PSHAb0549.
NMPDR	fig|326442.4.peg.3474.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q3ICJ5.
OMA	IATRINH.
Enzyme and pathway databases
BioCyc	PHAL326442:PSHAB0549-MON.
Family and domain databases
HAMAP	MF_01855. [Tree]
InterPro	IPR000146. Fructose_bisphosphatase. IPR020548. Fructose_bisphosphatase_AS. [Graphical view]
PANTHER	PTHR11556. In_FB_phphtase. 1 hit.
Pfam	PF00316. FBPase. 1 hit. [Graphical view]
PRINTS	PR00115. F16BPHPHTASE.
ProDom	PD001491. In_FB_phphtase. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00124. FBPASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

F16A3_PSEHT

Accession

Primary (citable) accession number: Q3ICJ5

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 3, 2009
Last sequence update:	November 8, 2005
Last modified:	November 3, 2009
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)