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Protein
Submitted name:

Prostate-specific transglutaminase 4

Gene

TGM4

Organism
Pan paniscus (Pygmy chimpanzee) (Bonobo)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Cofactori

Ca2+UniRule annotationNote: Binds 1 Ca2+ ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei268UniRule annotation1
Active sitei327UniRule annotation1
Active sitei350UniRule annotation1
Metal bindingi390CalciumUniRule annotation1
Metal bindingi392CalciumUniRule annotation1
Metal bindingi442CalciumUniRule annotation1
Metal bindingi447CalciumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferaseImported, Transferase
LigandCalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Prostate-specific transglutaminase 4Imported (EC:2.3.2.13Imported)
Gene namesi
Name:TGM4Imported
OrganismiPan paniscus (Pygmy chimpanzee) (Bonobo)Imported
Taxonomic identifieri9597 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini260 – 353TGcInterPro annotationAdd BLAST94

Phylogenomic databases

HOVERGENiHBG004342
KOiK05621
OrthoDBiEOG091G030K

Family and domain databases

Gene3Di2.60.40.10, 3 hits
3.90.260.10, 1 hit
InterProiView protein in InterPro
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR002931 Transglutaminase-like
IPR036985 Transglutaminase-like_sf
IPR023608 Transglutaminase_animal
IPR013808 Transglutaminase_AS
IPR008958 Transglutaminase_C
IPR036238 Transglutaminase_C_sf
IPR001102 Transglutaminase_N
PfamiView protein in Pfam
PF00927 Transglut_C, 1 hit
PF01841 Transglut_core, 1 hit
PF00868 Transglut_N, 1 hit
PIRSFiPIRSF000459 TGM_EBP42, 1 hit
SMARTiView protein in SMART
SM00460 TGc, 1 hit
SUPFAMiSSF49309 SSF49309, 2 hits
SSF81296 SSF81296, 1 hit
PROSITEiView protein in PROSITE
PS00547 TRANSGLUTAMINASES, 1 hit

Sequencei

Sequence statusi: Fragment.

Q3I1X5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMDASKELQV LHVDFLKQDN AVSHHTWEFQ TSTPVFRRGQ VFHLRLVLNQ
60 70 80 90 100
PLQSYHQLKL EFSTGPNPSI AKHTVVVLDL RTPSDHYNWQ ATLQNESGKE
110 120 130 140 150
VTVAVTSSPN AILGKYQLNV KTGNHILKSE ENILYLLFNP WCKEDMVFMP
160 170 180 190 200
DEDERKEYIL NDTGCHYVGA ARSIKYKPWN FGQFEKNVLD CCISLLTESS
210 220 230 240 250
LKPTDRRDPV LVCRAMCAMM SFEKGQGVLI GNWTGDYEGG TAPYKWTGSA
260 270 280 290 300
PILQQYYNTK QAVCFGQCWV FAGILTTVLR ALGIPARSVT GFDSAHDTER
310 320 330 340 350
NLTVDTYVNE NGEKITNMTH DSVWNFHVWT DAWMKRPDLP KGYDGWQAVD
360 370 380 390 400
ATPQERSQGV FCCGPSPLTA IRKGDIFIVY DTRFVFSEVN GDRLIWLVKM
410 420 430 440 450
VNGQEELHVI SMETTSIGKN ISTKAVGQDR RRDITYEYKY PEGSSEERQV
460 470 480 490 500
MDHAFLLLSS EREHRRPVKE NFLHMSVQSD DVLLGNPVNF TVILKRKTAA
510 520 530 540 550
LQNVNILGSF ELQLYTGKKV AKLCDLNKTS QIQGQVSEVT LTLDSKTYIN
560 570 580 590 600
SLAILDDEPV IRGFIIAEIV ESKEIMASEV FMSFQYPEFS IELPNTGRIG
610 620 630 640 650
QLLVCNCIFK NTLAIPLTDV KFSLESLGIS SLQTSDHGTV QPGETIQSQI
660 670 680
KCTPIKTGPK KFIVKLSSKQ VKEINAQKIV LITK
Length:684
Mass (Da):77,256
Last modified:November 8, 2005 - v1
Checksum:iBCA62E0352DE68D6
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei684Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ150487 Genomic DNA Translation: AAZ82263.1
EU685247 Genomic DNA Translation: ACF75755.1
RefSeqiXP_003809365.1, XM_003809317.2

Genome annotation databases

EnsembliENSPPAT00000058494; ENSPPAP00000035605; ENSPPAG00000040609
GeneIDi100980699
KEGGipps:100980699

Similar proteinsi

Entry informationi

Entry nameiQ3I1X5_PANPA
AccessioniPrimary (citable) accession number: Q3I1X5
Entry historyiIntegrated into UniProtKB/TrEMBL: November 8, 2005
Last sequence update: November 8, 2005
Last modified: April 25, 2018
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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