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Protein
Submitted name:

Prostate-specific transglutaminase 4

Gene

TGM4

Organism
Pan paniscus (Pygmy chimpanzee) (Bonobo)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei268 – 2681UniRule annotation
Active sitei327 – 3271UniRule annotation
Active sitei350 – 3501UniRule annotation

GO - Molecular functioni

  1. protein-glutamine gamma-glutamyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. peptide cross-linking Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AcyltransferaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Prostate-specific transglutaminase 4Imported (EC:2.3.2.13Imported)
Gene namesi
Name:TGM4Imported
OrganismiPan paniscus (Pygmy chimpanzee) (Bonobo)Imported
Taxonomic identifieri9597 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG004342.
KOiK05621.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 1 hit.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q3I1X5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MMDASKELQV LHVDFLKQDN AVSHHTWEFQ TSTPVFRRGQ VFHLRLVLNQ
60 70 80 90 100
PLQSYHQLKL EFSTGPNPSI AKHTVVVLDL RTPSDHYNWQ ATLQNESGKE
110 120 130 140 150
VTVAVTSSPN AILGKYQLNV KTGNHILKSE ENILYLLFNP WCKEDMVFMP
160 170 180 190 200
DEDERKEYIL NDTGCHYVGA ARSIKYKPWN FGQFEKNVLD CCISLLTESS
210 220 230 240 250
LKPTDRRDPV LVCRAMCAMM SFEKGQGVLI GNWTGDYEGG TAPYKWTGSA
260 270 280 290 300
PILQQYYNTK QAVCFGQCWV FAGILTTVLR ALGIPARSVT GFDSAHDTER
310 320 330 340 350
NLTVDTYVNE NGEKITNMTH DSVWNFHVWT DAWMKRPDLP KGYDGWQAVD
360 370 380 390 400
ATPQERSQGV FCCGPSPLTA IRKGDIFIVY DTRFVFSEVN GDRLIWLVKM
410 420 430 440 450
VNGQEELHVI SMETTSIGKN ISTKAVGQDR RRDITYEYKY PEGSSEERQV
460 470 480 490 500
MDHAFLLLSS EREHRRPVKE NFLHMSVQSD DVLLGNPVNF TVILKRKTAA
510 520 530 540 550
LQNVNILGSF ELQLYTGKKV AKLCDLNKTS QIQGQVSEVT LTLDSKTYIN
560 570 580 590 600
SLAILDDEPV IRGFIIAEIV ESKEIMASEV FMSFQYPEFS IELPNTGRIG
610 620 630 640 650
QLLVCNCIFK NTLAIPLTDV KFSLESLGIS SLQTSDHGTV QPGETIQSQI
660 670 680
KCTPIKTGPK KFIVKLSSKQ VKEINAQKIV LITK
Length:684
Mass (Da):77,256
Last modified:November 8, 2005 - v1
Checksum:iBCA62E0352DE68D6
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei684 – 6841Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ150487 Genomic DNA. Translation: AAZ82263.1.
EU685247 Genomic DNA. Translation: ACF75755.1.
RefSeqiXP_003809365.1. XM_003809317.2.

Genome annotation databases

GeneIDi100980699.
KEGGipps:100980699.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ150487 Genomic DNA. Translation: AAZ82263.1.
EU685247 Genomic DNA. Translation: ACF75755.1.
RefSeqiXP_003809365.1. XM_003809317.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100980699.
KEGGipps:100980699.

Organism-specific databases

CTDi7047.

Phylogenomic databases

HOVERGENiHBG004342.
KOiK05621.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 1 hit.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Pervasive Adaptive Evolution in Primate Seminal Proteins."
    Clark N.L., Swanson W.J.
    PLoS Genet. 1:E35-E35(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Hominoid seminal protein evolution and ancestral mating behavior."
    Carnahan S.J., Jensen-Seaman M.I.
    Am. J. Primatol. 70:939-948(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ3I1X5_PANPA
AccessioniPrimary (citable) accession number: Q3I1X5
Entry historyi
Integrated into UniProtKB/TrEMBL: November 8, 2005
Last sequence update: November 8, 2005
Last modified: January 7, 2015
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.