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Q3I1X5

- Q3I1X5_PANPA

UniProt

Q3I1X5 - Q3I1X5_PANPA

Protein
Submitted name:

Prostate-specific transglutaminase 4

Gene

TGM4

Organism
Pan paniscus (Pygmy chimpanzee) (Bonobo)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (08 Nov 2005)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 calcium ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei268 – 2681UniRule annotation
    Active sitei268 – 2681 By similarity
    Active sitei327 – 3271UniRule annotation
    Active sitei350 – 3501UniRule annotation
    Active sitei350 – 3501 By similarity
    Metal bindingi390 – 3901Calcium
    Metal bindingi392 – 3921Calcium
    Metal bindingi442 – 4421Calcium
    Metal bindingi447 – 4471Calcium

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein-glutamine gamma-glutamyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. peptide cross-linking Source: InterPro

    Keywords - Molecular functioni

    AcyltransferaseImported, Transferase

    Keywords - Ligandi

    CalciumUniRule annotation, Metal-bindingUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Prostate-specific transglutaminase 4Imported (EC:2.3.2.13Imported)
    Gene namesi
    Name:TGM4Imported
    OrganismiPan paniscus (Pygmy chimpanzee) (Bonobo)Imported
    Taxonomic identifieri9597 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG004342.
    KOiK05621.

    Family and domain databases

    Gene3Di2.60.40.10. 3 hits.
    3.90.260.10. 1 hit.
    InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
    IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    IPR002931. Transglutaminase-like.
    IPR008958. Transglutaminase_C.
    IPR013808. Transglutaminase_CS.
    IPR001102. Transglutaminase_N.
    [Graphical view]
    PANTHERiPTHR11590. PTHR11590. 1 hit.
    PfamiPF00927. Transglut_C. 1 hit.
    PF01841. Transglut_core. 1 hit.
    PF00868. Transglut_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
    SMARTiSM00460. TGc. 1 hit.
    [Graphical view]
    SUPFAMiSSF49309. SSF49309. 2 hits.
    SSF81296. SSF81296. 1 hit.
    PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q3I1X5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MMDASKELQV LHVDFLKQDN AVSHHTWEFQ TSTPVFRRGQ VFHLRLVLNQ    50
    PLQSYHQLKL EFSTGPNPSI AKHTVVVLDL RTPSDHYNWQ ATLQNESGKE 100
    VTVAVTSSPN AILGKYQLNV KTGNHILKSE ENILYLLFNP WCKEDMVFMP 150
    DEDERKEYIL NDTGCHYVGA ARSIKYKPWN FGQFEKNVLD CCISLLTESS 200
    LKPTDRRDPV LVCRAMCAMM SFEKGQGVLI GNWTGDYEGG TAPYKWTGSA 250
    PILQQYYNTK QAVCFGQCWV FAGILTTVLR ALGIPARSVT GFDSAHDTER 300
    NLTVDTYVNE NGEKITNMTH DSVWNFHVWT DAWMKRPDLP KGYDGWQAVD 350
    ATPQERSQGV FCCGPSPLTA IRKGDIFIVY DTRFVFSEVN GDRLIWLVKM 400
    VNGQEELHVI SMETTSIGKN ISTKAVGQDR RRDITYEYKY PEGSSEERQV 450
    MDHAFLLLSS EREHRRPVKE NFLHMSVQSD DVLLGNPVNF TVILKRKTAA 500
    LQNVNILGSF ELQLYTGKKV AKLCDLNKTS QIQGQVSEVT LTLDSKTYIN 550
    SLAILDDEPV IRGFIIAEIV ESKEIMASEV FMSFQYPEFS IELPNTGRIG 600
    QLLVCNCIFK NTLAIPLTDV KFSLESLGIS SLQTSDHGTV QPGETIQSQI 650
    KCTPIKTGPK KFIVKLSSKQ VKEINAQKIV LITK 684
    Length:684
    Mass (Da):77,256
    Last modified:November 8, 2005 - v1
    Checksum:iBCA62E0352DE68D6
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei684 – 6841Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DQ150487 Genomic DNA. Translation: AAZ82263.1.
    EU685247 Genomic DNA. Translation: ACF75755.1.
    RefSeqiXP_003809365.1. XM_003809317.1.

    Genome annotation databases

    GeneIDi100980699.
    KEGGipps:100980699.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DQ150487 Genomic DNA. Translation: AAZ82263.1 .
    EU685247 Genomic DNA. Translation: ACF75755.1 .
    RefSeqi XP_003809365.1. XM_003809317.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 100980699.
    KEGGi pps:100980699.

    Organism-specific databases

    CTDi 7047.

    Phylogenomic databases

    HOVERGENi HBG004342.
    KOi K05621.

    Family and domain databases

    Gene3Di 2.60.40.10. 3 hits.
    3.90.260.10. 1 hit.
    InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
    IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    IPR002931. Transglutaminase-like.
    IPR008958. Transglutaminase_C.
    IPR013808. Transglutaminase_CS.
    IPR001102. Transglutaminase_N.
    [Graphical view ]
    PANTHERi PTHR11590. PTHR11590. 1 hit.
    Pfami PF00927. Transglut_C. 1 hit.
    PF01841. Transglut_core. 1 hit.
    PF00868. Transglut_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
    SMARTi SM00460. TGc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49309. SSF49309. 2 hits.
    SSF81296. SSF81296. 1 hit.
    PROSITEi PS00547. TRANSGLUTAMINASES. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Pervasive Adaptive Evolution in Primate Seminal Proteins."
      Clark N.L., Swanson W.J.
      PLoS Genet. 1:E35-E35(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
    2. "Hominoid seminal protein evolution and ancestral mating behavior."
      Carnahan S.J., Jensen-Seaman M.I.
      Am. J. Primatol. 70:939-948(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ3I1X5_PANPA
    AccessioniPrimary (citable) accession number: Q3I1X5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 8, 2005
    Last sequence update: November 8, 2005
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)