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Q3HYJ3 (Q3HYJ3_STREE) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:parC EMBL AAZ93278.1
OrganismStreptococcus pneumoniae EMBL AAZ93278.1
Taxonomic identifier1313 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

Protein attributes

Sequence length820 AA.
Sequence statusFragment.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

ATP-dependent breakage, passage and rejoining of double-stranded DNA. SAAS SAAS006691

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL AAZ93278.1

Sequences

Sequence LengthMass (Da)Tools
Q3HYJ3 [UniParc].

Last modified November 8, 2005. Version 1.
Checksum: 18D452B5041F82FD

FASTA82092,789
        10         20         30         40         50         60 
IQNMSLEDIM GERFGRYSKY IIQDRALPDI RDGLKPVQRR ILYSMNKDSN TFDKSYRKSA 

        70         80         90        100        110        120 
KSVGNIMGNF HPHGDSSIYD AMVRMSQNWK NREILVEMHG NNGSMDGDPP AAMRYTEARL 

       130        140        150        160        170        180 
SEIAGYLLQD IEKKTVPFAW NFDDTEKEPT VLPAAFPNLL VNGSTGISAG YATDIPPHNL 

       190        200        210        220        230        240 
AEVIDAAVYM IDHPTAKIDK LMEFLPGPDF PTGAIIQGRD EIKKAYETGK GRVVVRSKTE 

       250        260        270        280        290        300 
IEKLKGGKEQ IVITEIPYEI NKANLVKKID DVRVNNKVAG IAEVRDESDR DGLRIAIELK 

       310        320        330        340        350        360 
KDANTELVLN YLFKYTDLQI NYNFNMVAID NFTPRQVGIV PILSSYIAHR REVILARSRF 

       370        380        390        400        410        420 
DKEKAEKRLH IVEGLIRVIS ILDEVIALIR ASENKADAKE NLKVSYDFTE EQAEAIVTLQ 

       430        440        450        460        470        480 
LYRLTNTDVV VLQEEEAELR EKIAMLAAII GDERTMYNLM KKELREVKKK FATPRLSSLE 

       490        500        510        520        530        540 
DTAKAIEIDT ASLIAEEDTY VSVTKAGYIK RTSPRSFAAS TLEEIGKRDD DRLIFVQSAK 

       550        560        570        580        590        600 
TTQHLLMFTS LGNVIYRPIH ELADIRWKDI GEHLSQTITN FETNEEILYV EVLDQFDDAT 

       610        620        630        640        650        660 
TYFAVTRLGQ IKRVERKEFT PWRTYRSKSV KYAKLKDDTD QIVAVAPIKL DDVVLVSQNG 

       670        680        690        700        710        720 
YALRFNIEEV PVVGAKAAGV KAMNLKEDDV LQSGFICNTS SFYLLTQRGS LKRVSIEEIL 

       730        740        750        760        770        780 
ATSRAKRGLQ VLRELKNKPH RVFLAGAVAE QGFVGDFFST EVDVNDQTLL VQSNKGTIYE 

       790        800        810        820 
SRLQDLNLSE RTSNGSFISD TISDEEVFDA YLQEVVTEDK 

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References

[1]"Molecular evolution perspectives on intraspecific lateral DNA transfer of topoisomerase and gyrase loci in Streptococcus pneumoniae, with implications for fluoroquinolone resistance development and spread."
Stanhope M.J., Walsh S.L., Becker J.A., Italia M.J., Ingraham K.A., Gwynn M.N., Mathie T., Poupard J.A., Miller L.A., Brown J.R., Amrine-Madsen H.
Antimicrob. Agents Chemother. 49:4315-4326(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: 0.15GR00S EMBL AAZ93278.1.
[2]"Breakage-reunion domain of Streptococcus pneumoniae topoisomerase IV: crystal structure of a gram-positive quinolone target."
Laponogov I., Veselkov D.A., Sohi M.K., Pan X.S., Achari A., Yang C., Ferrara J.D., Fisher L.M., Sanderson M.R.
PLoS ONE 2:E301-E301(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.67 ANGSTROMS) OF 1-493.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DQ176455 Genomic DNA. Translation: AAZ93278.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2NOVX-ray2.67A/B/C/D1-493[»]
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.30.1360.40. 1 hit.
3.90.199.10. 2 hits.
HAMAPMF_00937. ParC_type2.
InterProIPR024946. Arg_repress_C-like.
IPR006691. GyrA/parC_pinwhl.
IPR002205. Topo_IIA_A/C.
IPR013758. Topo_IIA_A/C_ab.
IPR013760. Topo_IIA_like_dom.
IPR005741. TopoIV_A_Gpos.
[Graphical view]
PfamPF03989. DNA_gyraseA_C. 5 hits.
PF00521. DNA_topoisoIV. 1 hit.
[Graphical view]
SMARTSM00434. TOP4c. 1 hit.
[Graphical view]
SUPFAMSSF56719. SSF56719. 1 hit.
TIGRFAMsTIGR01061. parC_Gpos. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ3HYJ3_STREE
AccessionPrimary (citable) accession number: Q3HYJ3
Entry history
Integrated into UniProtKB/TrEMBL: November 8, 2005
Last sequence update: November 8, 2005
Last modified: April 16, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)