Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Genome polyprotein

Gene

RHDV

Organism
Rabbit hemorrhagic disease virus (RHDV)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Nucleotidyltransferase, Protease, RNA-directed RNA polymeraseSAAS annotation, Thiol proteaseSAAS annotation, Transferase
Biological processViral RNA replicationSAAS annotation
LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Genome polyproteinSAAS annotation
Gene namesi
Name:RHDVImported
OrganismiRabbit hemorrhagic disease virus (RHDV)Imported
Taxonomic identifieri11976 [NCBI]
Taxonomic lineageiVirusesssRNA virusesssRNA positive-strand viruses, no DNA stageCaliciviridaeLagovirus
Virus hostiOryctolagus cuniculus (Rabbit) [TaxID: 9986]
Proteomesi
  • UP000171525 Componenti: Genome

Subcellular locationi

  • Virion SAAS annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei373 – 393HelicalSequence analysisAdd BLAST21
Transmembranei405 – 426HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

Keywords - Cellular componenti

Capsid proteinSAAS annotation, Membrane, Virion

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4EGTX-ray2.00A/B1993-2344[»]
4EJRX-ray2.00A/B1766-1995[»]
ProteinModelPortaliQ3HNQ2
SMRiQ3HNQ2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini492 – 653SF3 helicaseInterPro annotationAdd BLAST162
Domaini1495 – 1619RdRp catalyticInterPro annotationAdd BLAST125

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

CDDicd00205 rhv_like, 1 hit
Gene3Di2.60.120.20, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR004005 Calicivirus_coat
IPR004004 Helic/Pol/Pept_Calicivir-typ
IPR000605 Helicase_SF3_ssDNA/RNA_vir
IPR014759 Helicase_SF3_ssRNA_vir
IPR027417 P-loop_NTPase
IPR000317 Peptidase_C24
IPR009003 Peptidase_S1_PA
IPR033703 Rhv-like
IPR001205 RNA-dir_pol_C
IPR007094 RNA-dir_pol_PSvirus
IPR029053 Viral_coat
PfamiView protein in Pfam
PF00915 Calici_coat, 1 hit
PF03510 Peptidase_C24, 1 hit
PF00680 RdRP_1, 1 hit
PF00910 RNA_helicase, 1 hit
PRINTSiPR00916 2CENDOPTASE
PR00918 CALICVIRUSNS
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF50494 SSF50494, 1 hit
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS50507 RDRP_SSRNA_POS, 1 hit
PS51218 SF3_HELICASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q3HNQ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPPMSRLIGM TTAILPEKKP LSFFLDLRDK TPPCCIRATG ELAWPVFLGQ
60 70 80 90 100
NENEGLLETC DKCGKWLNGF GNFGLEDLGN VCLCSIAQQK HKFGPVCLCN
110 120 130 140 150
RAYIHDCGRW RRRSRFLKHY KALNKVIPCA YQFDEGSSPS VFEGEVDDLF
160 170 180 190 200
VELGAPTSMG FMDKKLLKKG KKLMDKFVDV DEPCLTSRDA GLLDSIASDN
210 220 230 240 250
TIRAKLEEEY GIEMVQAARD RKDFMKNLRL ALDNRPANPV TWYTKLGNIT
260 270 280 290 300
DKGKQWAKKV VYGACKATEP LKTLASILLV GLHNVIAVDT TVMLSTFKPV
310 320 330 340 350
NLLAILMDWT NDLTGFVTTL VRLLELYGVV QVTVNLIIEG VKSFWDKVIC
360 370 380 390 400
ATDRCFDLLK RLFDTFEDSV PTGPTAGCLI FMAFVFSTVV GYLPNNNVIT
410 420 430 440 450
TFMKGAGKLT TFAGVIGAIR TLWITINQHM VAKDLTSIQQ KVMTVVKMAN
460 470 480 490 500
EAATLDQLEI VSCLCSDLEN TLTNRCTLPS YNQHLGILNA SQKVVSDLHT
510 520 530 540 550
MVLGKINMTK QRPQPVAVIF KGAPGIGKTH LVHRIARDLG CQHPSTINFG
560 570 580 590 600
LDHFDSYTGE EVAIADEFNT CGDGESWVEL FIQMVNTNPC PLNCDKVENK
610 620 630 640 650
NKVFNSKYLL CTTNSNTILN ATHPRAGAFY RRVLIVEARN KAVESWQATR
660 670 680 690 700
HGSRPGKSCY SKDMSHLTFQ VYPHNMPAPG FVFVGDKLVR SQVAPREYKY
710 720 730 740 750
SELLDLIKSE HPDVASFEGA NKFNFIYPDA QYEQALLMWK QYFVMYGCVA
760 770 780 790 800
RLAKNFVDDI PYNQVHISKA SDPKIDGCVE YQCKFQHLWR MVPQFVLGCV
810 820 830 840 850
NMTNQLGTPL TQQQLDRITN GVEGVTVTTV NNILPFHSQT TLINPSFIKL
860 870 880 890 900
IWAVRKHLKG LSGVTKVAQF IWRVMTNPVD AYGSLVRTLT GAATFSDNPV
910 920 930 940 950
STTIICSNCT IQIHSCGGLL VRYSRDPVPV ASDNADRGDQ GVDVFTDPNL
960 970 980 990 1000
ISGFSWRRIA HLFVEVISHL CANHLVNLAT MAALGAVATK AFQGVKGKTK
1010 1020 1030 1040 1050
RGRGARVNLG NDEYDEWQAA RREFVNAHDM TAEEYLAMKN KAAMGSDDQD
1060 1070 1080 1090 1100
SVMFRSWWTR RQLRPDEDQV TIVGRGGVRN EVIRTRARQA PKGPKTLDDG
1110 1120 1130 1140 1150
GFYDNDYEGL PGFMRHNGSG WMIHIGNGLY ISNTHTARSS CSEIVTCSPT
1160 1170 1180 1190 1200
TDLCLVKGEI IRSVAQIAEG TPVCDWKKSP ISTYGIKKTL SDSTKIDVLA
1210 1220 1230 1240 1250
YDGCTQTTHG DCGLPLYDSS GKIVAIHTGK LLGFSKMCTL VDLTITKGVY
1260 1270 1280 1290 1300
ETSNFFCGEP IDYRGITAHR LVGAEPRPPV SGTRYARVPG VPDEYRTGYR
1310 1320 1330 1340 1350
PANLGRGDPD SDKSLMNIAV KSLQVYQQEP KLDKVDEFIE RAAADVLGYL
1360 1370 1380 1390 1400
RFLTKGERQV NLNFKAAFNT LDLSTSCGPF VPGKKIDHIK DGVMDQVLAK
1410 1420 1430 1440 1450
HLYKCWSVAN SGKALHHIYA CGLKDELRPL DKVKEGKKRL LWGCDVGVAV
1460 1470 1480 1490 1500
CAAAVFHNIC YKLKMVARFG PIAVGVDMTS RDFDVIINNL TVKASDFLCL
1510 1520 1530 1540 1550
DYSKWDSTMS PCVVRLAIDI LADCCEQTEL TKSVVLTLKS HPMTILDAMI
1560 1570 1580 1590 1600
VQTKRGLPSG MPFTSVINSI CHWLLWSAAV YKSCAEIGLH CSNLYEDAPF
1610 1620 1630 1640 1650
YTYGDDGVYA MTPMMVSLLP AIIENLRDYG LSPTAADKTE FIDVCPLNKI
1660 1670 1680 1690 1700
SFLKRTFELT DIGWVSKLDK SSILRQLEWS KTTSRHMVIE ETYDLAKEER
1710 1720 1730 1740 1750
GVQLEELQVA AAAHGQEFFN FVRKELERQQ AYTQFSVYSY DAARKVLADR
1760 1770 1780 1790 1800
KRVVSVVPDD EFVNVMEGKT RTAPQGEAAG TATTASVPGT TTDGMDPGVV
1810 1820 1830 1840 1850
AATSVVTAEN SSASVATAGI GGPPQQVDQQ ETWRTNFYYN DVFTWSVADA
1860 1870 1880 1890 1900
PGSILYTVQH SPQNNPFTAV LSQMYAGWAG GMQFRFIVAG SGVFGGRLVA
1910 1920 1930 1940 1950
AVIPPGIEIG PGLEVRQFPH VVIDARSLEP VTITMPDLRP NMYHPTGDPG
1960 1970 1980 1990 2000
LVPTLVLSVY NNLINPFGGS TNAIQVTVET RPSDDFEFVM IRAPSSKTVD
2010 2020 2030 2040 2050
SISPAGLLTT PVLTGVGNDN RWNGQIVGLQ PVPGGFSTCN RHWNLNGSTY
2060 2070 2080 2090 2100
GWSSPRFADI DHRRGSASYS GNSSTNVLQF WYANAGSAID NPISQVAPDG
2110 2120 2130 2140 2150
FPDMSFVPFN SPNIPTAGWV GFGGIWNSNN GAPAATTVQA YELGFATGAP
2160 2170 2180 2190 2200
NNLQPTTNTS GAQTVAKSIY AVVTGTNQNP TGLFVMASGV ISTPNASAVT
2210 2220 2230 2240 2250
YTPQPDRIVT TPGTPAAAPV GKNTPIMFAS VVRRTGDVNA AAGSTNGTQY
2260 2270 2280 2290 2300
GTGSQPLPVT IGLSLNNYSS ALMPGQFFVW QLTFASGFME IGLSVDGYFY
2310 2320 2330 2340
AGTGASTTLI DLTELIDVRP VGPRPSKSTL VFNLGGTTNG FSYV
Length:2,344
Mass (Da):257,035
Last modified:November 8, 2005 - v1
Checksum:iB5E2D9F0570D50EE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ205345 mRNA Translation: ABA46865.1

Similar proteinsi

Entry informationi

Entry nameiQ3HNQ2_RHDV
AccessioniPrimary (citable) accession number: Q3HNQ2
Entry historyiIntegrated into UniProtKB/TrEMBL: November 8, 2005
Last sequence update: November 8, 2005
Last modified: April 25, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health