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Q3EYR7 (Q3EYR7_BACTI) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Hydroxyethylthiazole kinase HAMAP-Rule MF_00228
EC=2.7.1.50 HAMAP-Rule MF_00228
Alternative name(s):
4-methyl-5-beta-hydroxyethylthiazole kinase HAMAP-Rule MF_00228
Gene names
Name:thiM HAMAP-Rule MF_00228
ORF Names:RBTH_06999 EMBL EAO56443.1
OrganismBacillus thuringiensis serovar israelensis ATCC 35646 EMBL EAO56443.1
Taxonomic identifier339854 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group ›

Protein attributes

Sequence length272 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 4-methyl-5-(2-hydroxyethyl)thiazole = ADP + 4-methyl-5-(2-phosphonooxyethyl)thiazole. HAMAP-Rule MF_00228 SAAS SAAS000417

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00228 SAAS SAAS000417

Pathway

Cofactor biosynthesis; thiamine diphosphate biosynthesis; 4-methyl-5-(2-phosphoethyl)-thiazole from 5-(2-hydroxyethyl)-4-methylthiazole: step 1/1. HAMAP-Rule MF_00228 SAAS SAAS000417

Sequence similarities

Belongs to the Thz kinase family. HAMAP-Rule MF_00228

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. EMBL EAO56443.1

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Binding site481Substrate; via amide nitrogen By similarity HAMAP-Rule MF_00228
Binding site1241ATP By similarity HAMAP-Rule MF_00228
Binding site1701ATP By similarity HAMAP-Rule MF_00228
Binding site1971Substrate; via amide nitrogen By similarity HAMAP-Rule MF_00228

Sequences

Sequence LengthMass (Da)Tools
Q3EYR7 [UniParc].

Last modified November 8, 2005. Version 1.
Checksum: 7F54E4EEDA2A4F80

FASTA27228,730
        10         20         30         40         50         60 
MKRMNMKEIS KVVDLVRESN PLVHNITNVV VTNFTANGLL ALGASPVMAY AKEEVAEMAS 

        70         80         90        100        110        120 
IAGALVLNMG TLRPEEVEAM LLAGKSANVN NVPVLFDPVG AGATSYRTEV ARHIPAEIDL 

       130        140        150        160        170        180 
AIIRGNAAEI ANVINEKWEI KGVDAGTGNG NVVSIARQAA DELNTVAVIT GKEDVVTDGE 

       190        200        210        220        230        240 
RTVLIRNGHP ILTKVTGTGC LLTSVIGAFV AVEKDYVKAV VAALTFYGVA AELAAVKTVE 

       250        260        270 
KGPGSFQIEF LNQLANTTSA DIEKYGKIEE LE

« Hide

References

[1]"Comparative genome analysis of Bacillus cereus group genomes with Bacillus subtilis."
Anderson I., Sorokin A., Kapatral V., Reznik G., Bhattacharya A., Mikhailova N., Burd H., Joukov V., Kaznadzey D., Walunas T., D'Souza M., Larsen N., Pusch G., Liolios K., Grechkin Y., Lapidus A., Goltsman E., Chu L. expand/collapse author list , Fonstein M., Ehrlich D., Overbeek R., Kyrpides N., Ivanova N.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: ATCC 35646 EMBL EAO56443.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AAJM01000023 Genomic DNA. Translation: EAO56443.1.

3D structure databases

ProteinModelPortalQ3EYR7.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEAO56443; EAO56443; RBTH_06999.
PATRIC38345526. VBIBacThu7829_1088.

Enzyme and pathway databases

UniPathwayUPA00060; UER00139.

Family and domain databases

HAMAPMF_00228. Thz_kinase.
InterProIPR000417. Hyethyz_kinase.
[Graphical view]
PfamPF02110. HK. 1 hit.
[Graphical view]
PIRSFPIRSF000513. Thz_kinase. 1 hit.
PRINTSPR01099. HYETHTZKNASE.
TIGRFAMsTIGR00694. thiM. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ3EYR7_BACTI
AccessionPrimary (citable) accession number: Q3EYR7
Entry history
Integrated into UniProtKB/TrEMBL: November 8, 2005
Last sequence update: November 8, 2005
Last modified: April 3, 2013
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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