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Q3ECW8 (BGL01_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Beta-glucosidase 1

Short name=AtBGLU1
EC=3.2.1.21
Gene names
Name:BGLU1
Ordered Locus Names:At1g45191
ORF Names:T2P3
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length517 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Sequence similarities

Belongs to the glycosyl hydrolase 1 family.

Sequence caution

The sequence AEE32093.1 differs from that shown. Reason: Erroneous gene model prediction.

The sequence AEE32094.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
   Coding sequence diversityAlternative splicing
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   PTMDisulfide bond
Glycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processcarbohydrate metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionbeta-glucosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Alternative products

This entry describes 1 isoform produced by alternative splicing. [Select]

Note: A number of isoforms are produced. According to EST sequences.
Isoform 1 (identifier: Q3ECW8-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2222 Potential
Chain23 – 517495Beta-glucosidase 1
PRO_0000389563

Regions

Region458 – 4592Substrate binding By similarity

Sites

Active site1911Proton donor By similarity
Active site4061Nucleophile By similarity
Binding site481Substrate By similarity
Binding site1451Substrate By similarity
Binding site1901Substrate By similarity
Binding site3331Substrate By similarity
Binding site4511Substrate By similarity

Amino acid modifications

Glycosylation2161N-linked (GlcNAc...) Potential
Glycosylation2211N-linked (GlcNAc...) Potential
Glycosylation4411N-linked (GlcNAc...) Potential
Glycosylation4731N-linked (GlcNAc...) Potential
Glycosylation5121N-linked (GlcNAc...) Potential
Disulfide bond210 ↔ 217 By similarity

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified November 16, 2011. Version 2.
Checksum: 726DA4B0420B2EAC

FASTA51758,585
        10         20         30         40         50         60 
MEDVLTLITM IVLLLLAFHG FGKCSSDLYS RSDFPEGFVF GAGISAYQWE GAVDEDGRKP 

        70         80         90        100        110        120 
SVWDTFLHCR KMDNGDIACD GYHKYKEDVQ LMAETGLHTF RFSISWSRLI SNGRGSINPK 

       130        140        150        160        170        180 
GLQFYKNFIQ ELVKHGIEPH VTLHHYDFPQ YLEDDYGGWT NRKIIKDFTA YADVCFREFG 

       190        200        210        220        230        240 
NHVKFWTTIN EANIFTIGGY NDGNSPPGRC SFPGRNCTLG NSSTETYIVG HNLLLAHASV 

       250        260        270        280        290        300 
SRLYKQKYKD IQGGSVGFSL FAMNFTPSTN SKDDEIATKR ANDFYLGWML EPLIYGDYPD 

       310        320        330        340        350        360 
VMKRTIGSRL PVFSKEESEQ VKGSSDFIGV IHYLTALVTN IDINPSLSGI PDFNSDMGES 

       370        380        390        400        410        420 
INILSMRVRI SRLPNSDEKC LIFFITLSIL EYIKQSYGNP PVYILENGKT MNQDLELQQK 

       430        440        450        460        470        480 
DTPRIEYLDA YIGAVLKAVR NGSDTRGYFV WSFMDLYELL NGYKSSFGLY SVNFSDPHRK 

       490        500        510 
RSPKLSAHWY SGFLKGKPTF LGSQGITQLH SNFSSSR 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. expand/collapse author list , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Functional genomic analysis of Arabidopsis thaliana glycoside hydrolase family 1."
Xu Z., Escamilla-Trevino L.L., Zeng L., Lalgondar M., Bevan D.R., Winkel B.S.J., Mohamed A., Cheng C.-L., Shih M.-C., Poulton J.E., Esen A.
Plant Mol. Biol. 55:343-367(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC084820 Genomic DNA. No translation available.
CP002684 Genomic DNA. Translation: AEE32093.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE32094.1. Sequence problems.
RefSeqNP_849771.2. NM_179440.2.
NP_973974.2. NM_202245.2.
UniGeneAt.49953.

3D structure databases

ProteinModelPortalQ3ECW8.
SMRQ3ECW8. Positions 28-499.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING3702.AT1G45191.2-P.

Protein family/group databases

CAZyGH1. Glycoside Hydrolase Family 1.

Proteomic databases

PaxDbQ3ECW8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT1G45191.2; AT1G45191.2; AT1G45191.
GeneID841088.
KEGGath:AT1G45191.

Organism-specific databases

TAIRAT1G45191.

Phylogenomic databases

eggNOGCOG2723.
InParanoidQ3ECW8.
KOK01188.

Enzyme and pathway databases

BioCycARA:AT1G45191-MONOMER.
ARA:GQT-2218-MONOMER.

Gene expression databases

GenevestigatorQ3ECW8.

Family and domain databases

Gene3D3.20.20.80. 1 hit.
InterProIPR001360. Glyco_hydro_1.
IPR018120. Glyco_hydro_1_AS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERPTHR10353. PTHR10353. 1 hit.
PfamPF00232. Glyco_hydro_1. 1 hit.
[Graphical view]
PRINTSPR00131. GLHYDRLASE1.
SUPFAMSSF51445. SSF51445. 1 hit.
PROSITEPS00653. GLYCOSYL_HYDROL_F1_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBGL01_ARATH
AccessionPrimary (citable) accession number: Q3ECW8
Secondary accession number(s): F4HRB1, F4HRB2
Entry history
Integrated into UniProtKB/Swiss-Prot: November 24, 2009
Last sequence update: November 16, 2011
Last modified: June 11, 2014
This is version 63 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names