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Protein

Sugar transporter ERD6-like 5

Gene

At1g54730

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Sugar transporter.Curated

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Sugar transport, Transport

Enzyme and pathway databases

ReactomeiR-ATH-428790. Facilitative Na+-independent glucose transporters.
R-ATH-8856825. Cargo recognition for clathrin-mediated endocytosis.

Names & Taxonomyi

Protein namesi
Recommended name:
Sugar transporter ERD6-like 5
Gene namesi
Ordered Locus Names:At1g54730
ORF Names:T22H22.15
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRiAT1G54730.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei32 – 52Helical; Name=1Sequence analysisAdd BLAST21
Transmembranei68 – 88Helical; Name=2Sequence analysisAdd BLAST21
Transmembranei107 – 127Helical; Name=3Sequence analysisAdd BLAST21
Transmembranei130 – 150Helical; Name=4Sequence analysisAdd BLAST21
Transmembranei162 – 182Helical; Name=5Sequence analysisAdd BLAST21
Transmembranei185 – 205Helical; Name=6Sequence analysisAdd BLAST21
Transmembranei268 – 288Helical; Name=7Sequence analysisAdd BLAST21
Transmembranei303 – 323Helical; Name=8Sequence analysisAdd BLAST21
Transmembranei330 – 350Helical; Name=9Sequence analysisAdd BLAST21
Transmembranei369 – 389Helical; Name=10Sequence analysisAdd BLAST21
Transmembranei404 – 424Helical; Name=11Sequence analysisAdd BLAST21
Transmembranei430 – 450Helical; Name=12Sequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002598551 – 470Sugar transporter ERD6-like 5Add BLAST470

Proteomic databases

PaxDbiQ3ECP7.

Expressioni

Gene expression databases

GenevisibleiQ3ECP7. AT.

Interactioni

Protein-protein interaction databases

BioGridi27139. 7 interactors.
STRINGi3702.AT1G54730.2.

Structurei

3D structure databases

ProteinModelPortaliQ3ECP7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0254. Eukaryota.
ENOG410XNQK. LUCA.
HOGENOMiHOG000202868.
InParanoidiQ3ECP7.
OMAiAFYASAI.
OrthoDBiEOG093609LF.
PhylomeDBiQ3ECP7.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport-like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00879. SP. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
[Graphical view]

Sequences (3)i

Sequence statusi: Complete.

This entry describes 3 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q3ECP7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MRGEIDEANL APETSLINKE NQDSSATITT TLLLTTFVAV SGSFVFGSAI
60 70 80 90 100
GYSSPVQSDL TKELNLSVAE YSLFGSILTI GAMIGAAMSG RIADMIGRRA
110 120 130 140 150
TMGFSEMFCI LGWLAIYLSK VAIWLDVGRF LVGYGMGVFS FVVPVYIAEI
160 170 180 190 200
TPKGLRGGFT TVHQLLICLG VSVTYLLGSF IGWRILALIG MIPCVVQMMG
210 220 230 240 250
LFVIPESPRW LAKVGKWEEF EIALQRLRGE SADISYESNE IKDYTRRLTD
260 270 280 290 300
LSEGSIVDLF QPQYAKSLVV GVGLMVLQQF GGVNGIAFYA SSIFESAGVS
310 320 330 340 350
SKIGMIAMVV VQIPMTTLGV LLMDKSGRRP LLLISATGTC IGCFLVGLSF
360 370 380 390 400
SLQFVKQLSG DASYLALTGV LVYTGSFSLG MGGIPWVIMS EIFPIDIKGS
410 420 430 440 450
AGSLVTVVSW VGSWIISFTF NFLMNWNPAG TFYVFATVCG ATVIFVAKLV
460 470
PETKGRTLEE IQYSIGYVEL
Length:470
Mass (Da):50,740
Last modified:November 14, 2006 - v2
Checksum:i73A74F534EF3A0F9
GO
Isoform 2 (identifier: Q3ECP7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-82: Missing.
     392-414: IFPIDIKGSAGSLVTVVSWVGSW → VSNIHKNSLVLNILLYLIIRSMS
     415-470: Missing.

Note: No experimental confirmation available.
Show »
Length:332
Mass (Da):36,082
Checksum:i4428674C582261DA
GO
Isoform 3 (identifier: Q3ECP7-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-82: Missing.
     144-149: PVYIAE → KSINSS
     150-470: Missing.

Note: No experimental confirmation available.
Show »
Length:67
Mass (Da):7,301
Checksum:i8218C3A7E522B919
GO

Sequence cautioni

The sequence AAC64898 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAN15437 differs from that shown. Reason: Frameshift at several positions.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti269V → I in AAN15437 (PubMed:14593172).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0215461 – 82Missing in isoform 2 and isoform 3. 2 PublicationsAdd BLAST82
Alternative sequenceiVSP_021547144 – 149PVYIAE → KSINSS in isoform 3. 1 Publication6
Alternative sequenceiVSP_021548150 – 470Missing in isoform 3. 1 PublicationAdd BLAST321
Alternative sequenceiVSP_021549392 – 414IFPID…WVGSW → VSNIHKNSLVLNILLYLIIR SMS in isoform 2. 1 PublicationAdd BLAST23
Alternative sequenceiVSP_021550415 – 470Missing in isoform 2. 1 PublicationAdd BLAST56

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005388 Genomic DNA. Translation: AAC64898.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE33139.1.
CP002684 Genomic DNA. Translation: AEE33140.1.
CP002684 Genomic DNA. Translation: AEE33141.1.
AY054504 mRNA. Translation: AAK96695.1.
BT000118 mRNA. Translation: AAN15437.1. Frameshift.
BT025017 mRNA. Translation: ABE02392.1.
PIRiD96589.
RefSeqiNP_564666.1. NM_104349.2. [Q3ECP7-3]
NP_850964.1. NM_180633.2. [Q3ECP7-1]
UniGeneiAt.26473.

Genome annotation databases

EnsemblPlantsiAT1G54730.2; AT1G54730.2; AT1G54730. [Q3ECP7-1]
GeneIDi841914.
GrameneiAT1G54730.2; AT1G54730.2; AT1G54730.
KEGGiath:AT1G54730.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005388 Genomic DNA. Translation: AAC64898.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE33139.1.
CP002684 Genomic DNA. Translation: AEE33140.1.
CP002684 Genomic DNA. Translation: AEE33141.1.
AY054504 mRNA. Translation: AAK96695.1.
BT000118 mRNA. Translation: AAN15437.1. Frameshift.
BT025017 mRNA. Translation: ABE02392.1.
PIRiD96589.
RefSeqiNP_564666.1. NM_104349.2. [Q3ECP7-3]
NP_850964.1. NM_180633.2. [Q3ECP7-1]
UniGeneiAt.26473.

3D structure databases

ProteinModelPortaliQ3ECP7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi27139. 7 interactors.
STRINGi3702.AT1G54730.2.

Proteomic databases

PaxDbiQ3ECP7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G54730.2; AT1G54730.2; AT1G54730. [Q3ECP7-1]
GeneIDi841914.
GrameneiAT1G54730.2; AT1G54730.2; AT1G54730.
KEGGiath:AT1G54730.

Organism-specific databases

TAIRiAT1G54730.

Phylogenomic databases

eggNOGiKOG0254. Eukaryota.
ENOG410XNQK. LUCA.
HOGENOMiHOG000202868.
InParanoidiQ3ECP7.
OMAiAFYASAI.
OrthoDBiEOG093609LF.
PhylomeDBiQ3ECP7.

Enzyme and pathway databases

ReactomeiR-ATH-428790. Facilitative Na+-independent glucose transporters.
R-ATH-8856825. Cargo recognition for clathrin-mediated endocytosis.

Miscellaneous databases

PROiQ3ECP7.

Gene expression databases

GenevisibleiQ3ECP7. AT.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport-like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00879. SP. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiERDL5_ARATH
AccessioniPrimary (citable) accession number: Q3ECP7
Secondary accession number(s): Q8H197, Q940K3, Q9ZVM0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 14, 2006
Last sequence update: November 14, 2006
Last modified: November 30, 2016
This is version 81 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.