SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q3E834

- YOS1_YEAST

UniProt

Q3E834 - YOS1_YEAST

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Protein transport protein YOS1
Gene
YOS1, YER074W-A
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at protein leveli

Functioni

Required for protein transport between endoplasmic reticulum and Golgi apparatus.1 Publication

GO - Biological processi

  1. ER to Golgi vesicle-mediated transport Source: SGD
  2. protein transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

ER-Golgi transport, Protein transport, Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-30392-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein transport protein YOS1
Alternative name(s):
YIP one suppressor protein 1
Gene namesi
Name:YOS1
Ordered Locus Names:YER074W-A
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome V

Organism-specific databases

CYGDiYER074w-a.
SGDiS000007651. YOS1.

Subcellular locationi

Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein 1 Publication

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei2 – 2221Helical; Reviewed prediction
Add
BLAST
Transmembranei65 – 8521Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. ER to Golgi transport vesicle Source: SGD
  2. endoplasmic reticulum membrane Source: SGD
  3. integral component of Golgi membrane Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum, Golgi apparatus, Membrane

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Mutagenesisi18 – 181N → A in YOS1-1; impairs interaction with YIP1, blocks ER-Golgi protein transport, and causes a severe growth defect at 37 degrees Celsius. 1 Publication
Mutagenesisi69 – 691P → A: Lethal. 1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 8585Protein transport protein YOS1
PRO_0000232636Add
BLAST

Proteomic databases

PaxDbiQ3E834.

Expressioni

Gene expression databases

GenevestigatoriQ3E834.

Interactioni

Subunit structurei

Component of the YIP1-YIF1 complex, composed of at least YIF1, YIP1 and YOS1.

Protein-protein interaction databases

BioGridi36818. 4 interactions.
STRINGi4932.YER074W-A.

Structurei

3D structure databases

ProteinModelPortaliQ3E834.

Family & Domainsi

Sequence similaritiesi

Belongs to the YOS1 family.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG329574.
GeneTreeiENSGT00510000047648.
HOGENOMiHOG000192480.
OMAiFLNRIGW.
OrthoDBiEOG78WM5G.

Family and domain databases

InterProiIPR013880. Yos1.
[Graphical view]
PANTHERiPTHR15858. PTHR15858. 1 hit.
PfamiPF08571. Yos1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3E834-1 [UniParc]FASTAAdd to Basket

« Hide

MVLFGLGRLF YVILLLINAV AVLSEERFLR RIGLGRSNDE TPVFGQDQNT   50
TKSKVVQLIG AVQTLLRIPL IGINILVIVY ELLLG 85
Length:85
Mass (Da):9,436
Last modified:November 8, 2005 - v1
Checksum:i7AE4E85AD2B43787
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U18814 Genomic DNA. No translation available.
BK006939 Genomic DNA. Translation: DAA07734.1.
RefSeqiNP_219496.2. NM_001184512.1.

Genome annotation databases

EnsemblFungiiYER074W-A; YER074W-A; YER074W-A.
GeneIDi856806.
KEGGisce:YER074W-A.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U18814 Genomic DNA. No translation available.
BK006939 Genomic DNA. Translation: DAA07734.1 .
RefSeqi NP_219496.2. NM_001184512.1.

3D structure databases

ProteinModelPortali Q3E834.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 36818. 4 interactions.
STRINGi 4932.YER074W-A.

Proteomic databases

PaxDbi Q3E834.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YER074W-A ; YER074W-A ; YER074W-A .
GeneIDi 856806.
KEGGi sce:YER074W-A.

Organism-specific databases

CYGDi YER074w-a.
SGDi S000007651. YOS1.

Phylogenomic databases

eggNOGi NOG329574.
GeneTreei ENSGT00510000047648.
HOGENOMi HOG000192480.
OMAi FLNRIGW.
OrthoDBi EOG78WM5G.

Enzyme and pathway databases

BioCyci YEAST:G3O-30392-MONOMER.

Miscellaneous databases

NextBioi 983062.
PROi Q3E834.

Gene expression databases

Genevestigatori Q3E834.

Family and domain databases

InterProi IPR013880. Yos1.
[Graphical view ]
PANTHERi PTHR15858. PTHR15858. 1 hit.
Pfami PF08571. Yos1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. "Yos1p is a novel subunit of the Yip1p-Yif1p complex and is required for transport between the endoplasmic reticulum and the Golgi complex."
    Heidtman M., Chen C.Z., Collins R.N., Barlowe C.
    Mol. Biol. Cell 16:1673-1683(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, INTERACTION WITH YIF1 AND YIP1, SUBCELLULAR LOCATION, MUTAGENESIS OF ASN-18 AND PRO-69.

Entry informationi

Entry nameiYOS1_YEAST
AccessioniPrimary (citable) accession number: Q3E834
Secondary accession number(s): D3DLY0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 18, 2006
Last sequence update: November 8, 2005
Last modified: May 14, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome V
    Yeast (Saccharomyces cerevisiae) chromosome V: entries and gene names

External Data

Dasty 3

Similar proteinsi