Q3E7Y5 (YB111_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized helicase-like protein YBL111C

Gene names

Ordered Locus Names:

YBL111C

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	667 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Miscellaneous	Present with 279 molecules/cell in log phase SD medium. Ref.3
Sequence similarities	Belongs to the helicase family. Yeast subtelomeric Y' repeat subfamily. Contains 1 helicase ATP-binding domain.
Caution	Although strongly related to DNA helicases, it lacks the helicase C-terminal domain, suggesting that it has no helicase activity.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATP-dependent helicase activity Inferred from electronic annotation. Source: InterPro nucleic acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 667	667	Uncharacterized helicase-like protein YBL111C		PRO_0000248406
Regions
	Domain	375 – 552	178	Helicase ATP-binding
	Nucleotide binding	388 – 395	8	ATP Potential
	Motif	498 – 501	4	DEAH box

Sequences

	Sequence		Length	Mass (Da)
	Q3E7Y5 [UniParc]. Last modified November 8, 2005. Version 1. Checksum: C26A35A844F2841C	FASTA	667	76,246
	10 20 30 40 50 60 MKVSDRRKFE KANFDEFESA LNNKNDLVHC PSITLFESIP TEVRSFYEDE KSGLIKVVKF 70 80 90 100 110 120 RTGAMDRKRS FEKIVVSVMV GKNVQKFLTF VEDEPDFQGG PIPSKYLIPK KINLMVYTLF 130 140 150 160 170 180 QVHTLKFNRK DYDTLSLFYL NRGYYNELSF RVLERCYEIA SARPNDSSTM RTFTDFVSGT 190 200 210 220 230 240 PIVRSLQKST IRKYGYNLAP YMFLLLHVDE LSIFSAYQAS LPGEKKVDTE RLKRDLCPRK 250 260 270 280 290 300 PTEIKYFSQI CNDMMNKKDR LGDVLATAQR IRRRYNKNGS SEPRLKTLDG LTSERWIQWL 310 320 330 340 350 360 GLESDYHCSF SSTRNAEDVV AGEAASSDHD QKISRVTRKR PREPKSTNDI LVAGRKLFGS 370 380 390 400 410 420 SFEFRDLHQL RLCHEIYMAD TPSVAVQAPP GYGKTELFHL PLIALASKGD VKYVSFLFVP 430 440 450 460 470 480 YTVLLANCMI RLGRRGCLNV APVRNFIEEG CDGVTDLYVG IYDDLASTNF TDRIAAWENI 490 500 510 520 530 540 VECTFRTNNV KLGYLIVDEF HNFETEVYRQ SQFGGITNLD FDAFEKAIFL SGTAPEAVAD 550 560 570 580 590 600 AALQRIGLTG LAKKSMDINE LKRSEDLSRG LSSYPTRMFN LIKEKSEVPL GHVHKIWKKV 610 620 630 640 650 660 ESQPEEALKL LLALFEIEPE SKAIVVASTT NEVEELACSW RKYFRVVWIH GKLGCCRKGV SHKGVCH

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete DNA sequence of yeast chromosome II." Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C., Baur A., Becam A.-M., Biteau N., Boles E., Brandt T., Brendel M., Brueckner M., Bussereau F., Christiansen C., Contreras R., Crouzet M., Cziepluch C. , Demolis N., Delaveau T., Doignon F., Domdey H., Duesterhus S., Dubois E., Dujon B., El Bakkoury M., Entian K.-D., Feuermann M., Fiers W., Fobo G.M., Fritz C., Gassenhuber J., Glansdorff N., Goffeau A., Grivell L.A., de Haan M., Hein C., Herbert C.J., Hollenberg C.P., Holmstroem K., Jacq C., Jacquet M., Jauniaux J.-C., Jonniaux J.-L., Kallesoee T., Kiesau P., Kirchrath L., Koetter P., Korol S., Liebl S., Logghe M., Lohan A.J.E., Louis E.J., Li Z.Y., Maat M.J., Mallet L., Mannhaupt G., Messenguy F., Miosga T., Molemans F., Mueller S., Nasr F., Obermaier B., Perea J., Pierard A., Piravandi E., Pohl F.M., Pohl T.M., Potier S., Proft M., Purnelle B., Ramezani Rad M., Rieger M., Rose M., Schaaff-Gerstenschlaeger I., Scherens B., Schwarzlose C., Skala J., Slonimski P.P., Smits P.H.M., Souciet J.-L., Steensma H.Y., Stucka R., Urrestarazu L.A., van der Aart Q.J.M., Van Dyck L., Vassarotti A., Vetter I., Vierendeels F., Vissers S., Wagner G., de Wergifosse P., Wolfe K.H., Zagulski M., Zimmermann F.K., Mewes H.-W., Kleine K. EMBO J. 13:5795-5809(1994) [PubMed: 7813418] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: S288c / YPH1.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Y08934 Genomic DNA. No translation available. BK006936 Genomic DNA. Translation: DAA07014.1.
RefSeq	NP_009439.1. NM_001180052.1.
3D structure databases
ProteinModelPortal	Q3E7Y5.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q3E7Y5. 8 interactions.
MINT	MINT-2492850.
STRING	Q3E7Y5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YBL111C; YBL111C; YBL111C.
GeneID	852161.
KEGG	sce:YBL111C.
Organism-specific databases
CYGD	YBL111c.
SGD	S000002151. YBL111C.
Phylogenomic databases
eggNOG	COG0513.
GeneTree	EFGT00070000008730.
HOGENOM	HBG204195.
OrthoDB	EOG4V9Z0T.
Gene expression databases
Genevestigator	Q3E7Y5.
Family and domain databases
InterPro	IPR014001. DEAD-like_helicase. IPR011545. DNA/RNA_helicase_DEAD/DEAH_N. [Graphical view]
Pfam	PF00270. DEAD. 1 hit. [Graphical view]
SMART	SM00487. DEXDc. 1 hit. [Graphical view]
PROSITE	PS51192. HELICASE_ATP_BIND_1. False negative. [Graphical view]
ProtoNet	Search...
Other
NextBio	970600.

Entry information

Entry name

YB111_YEAST

Accession

Primary (citable) accession number: Q3E7Y5
Secondary accession number(s): D6VPP4

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 5, 2006
Last sequence update:	November 8, 2005
Last modified:	December 14, 2011
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program