Reviewed, UniProtKB/Swiss-Prot Q3E7Y4 (YB112_YEAST)

Names and origin

Protein names

Recommended name:
    Putative uncharacterized helicase-like protein YBL112C

Gene names

Ordered Locus Names:

YBL112C

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	105 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Uncertain.

General annotation (Comments)

Induction	Upon SUB2 overexpression. Ref.2
Sequence similarities	Belongs to the helicase family. Yeast subtelomeric Y' repeat subfamily. Contains 1 helicase C-terminal domain.
Caution	Although strongly related to DNA helicases, it lacks the helicase ATP-binding domains, suggesting that it has no helicase activity. Could be the product of a pseudogene.

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: InterPro helicase activity Inferred from electronic annotation. Source: InterPro nucleic acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 105	105	Putative uncharacterized helicase-like protein YBL112C		PRO_0000248407
Regions
	Domain	2 – 44	43	Helicase C-terminal

Sequences

	Sequence		Length	Mass (Da)
	Q3E7Y4-1 [UniParc]. Last modified November 8, 2005. Version 1. Checksum: 98A2C6CB2F7F3CEB	FASTA	105	11,974
	10 20 30 40 50 60 MQVLIGTKLV TEGIDIKQLM MVIMLDNRLN IIELIQGVGR LRDGGLCYLL SRKNSWAARN 70 80 90 100 RKGELPPIKE GCITEQVREF YGLESKKGKK GPACWMLWLQ DRPVC

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete DNA sequence of yeast chromosome II." Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C., Baur A., Becam A.-M., Biteau N., Boles E., Brandt T., Brendel M., Brueckner M., Bussereau F., Christiansen C., Contreras R., Crouzet M., Cziepluch C. , Demolis N., Delaveau T., Doignon F., Domdey H., Duesterhus S., Dubois E., Dujon B., El Bakkoury M., Entian K.-D., Feuermann M., Fiers W., Fobo G.M., Fritz C., Gassenhuber J., Glansdorff N., Goffeau A., Grivell L.A., de Haan M., Hein C., Herbert C.J., Hollenberg C.P., Holmstroem K., Jacq C., Jacquet M., Jauniaux J.-C., Jonniaux J.-L., Kallesoee T., Kiesau P., Kirchrath L., Koetter P., Korol S., Liebl S., Logghe M., Lohan A.J.E., Louis E.J., Li Z.Y., Maat M.J., Mallet L., Mannhaupt G., Messenguy F., Miosga T., Molemans F., Mueller S., Nasr F., Obermaier B., Perea J., Pierard A., Piravandi E., Pohl F.M., Pohl T.M., Potier S., Proft M., Purnelle B., Ramezani Rad M., Rieger M., Rose M., Schaaff-Gerstenschlaeger I., Scherens B., Schwarzlose C., Skala J., Slonimski P.P., Smits P.H.M., Souciet J.-L., Steensma H.Y., Stucka R., Urrestarazu L.A., van der Aart Q.J.M., Van Dyck L., Vassarotti A., Vetter I., Vierendeels F., Vissers S., Wagner G., de Wergifosse P., Wolfe K.H., Zagulski M., Zimmermann F.K., Mewes H.-W., Kleine K. EMBO J. 13:5795-5809(1994) [PubMed: 7813418] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: S288c / YPH1.
[2]	"The Saccharomyces cerevisiae Sub2 protein suppresses heterochromatic silencing at telomeres and subtelomeric genes." Lahue E., Heckathorn J., Meyer Z., Smith J., Wolfe C. Yeast 22:537-551(2005) [PubMed: 15942929] [Abstract] Cited for: INDUCTION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	Y08934 Genomic DNA. No translation available.
RefSeq	NP_009438.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-2966N.
STRING	Q3E7Y4.
Genome annotation databases
Ensembl	YBL112C; YBL112C; YBL112C; Saccharomyces cerevisiae. [Genome view] YHR218W-A; YHR218W-A; YHR218W-A; Saccharomyces cerevisiae. [Genome view]
GeneID	852160.
KEGG	sce:YBL112C.
Organism-specific databases
CYGD	YBL112c.
SGD	S000002152. YBL112C.
Phylogenomic databases
OrthoDB	EOG97WQ52.
Gene expression databases
Genevestigator	Q3E7Y4.
Family and domain databases
InterPro	IPR001650. DNA/RNA_helicase_C. [Graphical view]
Pfam	PF00271. Helicase_C. 1 hit. [Graphical view]
PROSITE	PS51194. HELICASE_CTER. False negative. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	970597.

Entry information

Entry name

YB112_YEAST

Accession

Primary (citable) accession number: Q3E7Y4

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 5, 2006
Last sequence update:	November 8, 2005
Last modified:	December 15, 2009
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)