Q3E7Y4 (YB112_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative uncharacterized helicase-like protein YBL112C

Gene names

Ordered Locus Names:

YBL112C

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	105 AA.
Sequence status	Complete.
Protein existence	Uncertain

General annotation (Comments)

Induction	Upon SUB2 overexpression. Ref.3
Sequence similarities	Belongs to the helicase family. Yeast subtelomeric Y' repeat subfamily. Contains 1 helicase C-terminal domain.
Caution	Although strongly related to DNA helicases, it lacks the helicase ATP-binding domains, suggesting that it has no helicase activity. Could be the product of a pseudogene.

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	ATP binding Inferred from electronic annotation. Source: InterPro helicase activity Inferred from electronic annotation. Source: InterPro nucleic acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 105	105	Putative uncharacterized helicase-like protein YBL112C		PRO_0000248407
Regions
	Domain	2 – 44	43	Helicase C-terminal

Sequences

	Sequence		Length	Mass (Da)
	Q3E7Y4 [UniParc]. Last modified November 8, 2005. Version 1. Checksum: 98A2C6CB2F7F3CEB	FASTA	105	11,974
	10 20 30 40 50 60 MQVLIGTKLV TEGIDIKQLM MVIMLDNRLN IIELIQGVGR LRDGGLCYLL SRKNSWAARN 70 80 90 100 RKGELPPIKE GCITEQVREF YGLESKKGKK GPACWMLWLQ DRPVC

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete DNA sequence of yeast chromosome II." Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C., Baur A., Becam A.-M., Biteau N., Boles E., Brandt T., Brendel M., Brueckner M., Bussereau F., Christiansen C., Contreras R., Crouzet M., Cziepluch C. , Demolis N., Delaveau T., Doignon F., Domdey H., Duesterhus S., Dubois E., Dujon B., El Bakkoury M., Entian K.-D., Feuermann M., Fiers W., Fobo G.M., Fritz C., Gassenhuber J., Glansdorff N., Goffeau A., Grivell L.A., de Haan M., Hein C., Herbert C.J., Hollenberg C.P., Holmstroem K., Jacq C., Jacquet M., Jauniaux J.-C., Jonniaux J.-L., Kallesoee T., Kiesau P., Kirchrath L., Koetter P., Korol S., Liebl S., Logghe M., Lohan A.J.E., Louis E.J., Li Z.Y., Maat M.J., Mallet L., Mannhaupt G., Messenguy F., Miosga T., Molemans F., Mueller S., Nasr F., Obermaier B., Perea J., Pierard A., Piravandi E., Pohl F.M., Pohl T.M., Potier S., Proft M., Purnelle B., Ramezani Rad M., Rieger M., Rose M., Schaaff-Gerstenschlaeger I., Scherens B., Schwarzlose C., Skala J., Slonimski P.P., Smits P.H.M., Souciet J.-L., Steensma H.Y., Stucka R., Urrestarazu L.A., van der Aart Q.J.M., Van Dyck L., Vassarotti A., Vetter I., Vierendeels F., Vissers S., Wagner G., de Wergifosse P., Wolfe K.H., Zagulski M., Zimmermann F.K., Mewes H.-W., Kleine K. EMBO J. 13:5795-5809(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: S288c / YPH1.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"The Saccharomyces cerevisiae Sub2 protein suppresses heterochromatic silencing at telomeres and subtelomeric genes." Lahue E., Heckathorn J., Meyer Z., Smith J., Wolfe C. Yeast 22:537-551(2005) [PubMed] [Europe PMC] [Abstract] Cited for: INDUCTION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Y08934 Genomic DNA. No translation available. BK006936 Genomic DNA. Translation: DAA07013.1.
RefSeq	NP_009438.1. NM_001180053.1.
3D structure databases
ProteinModelPortal	Q3E7Y4.
SMR	Q3E7Y4. Positions 2-61.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-2966N.
STRING	4932.YBL112C.
Proteomic databases
PaxDb	Q3E7Y4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YBL112C; YBL112C; YBL112C. YHR218W-A; YHR218W-A; YHR218W-A.
GeneID	852160.
KEGG	sce:YBL112C.
Organism-specific databases
CYGD	YBL112c. YHR218w-a.
SGD	S000002152. YBL112C.
Phylogenomic databases
eggNOG	COG0513.
GeneTree	ENSGT00390000002916.
Gene expression databases
Genevestigator	Q3E7Y4.
Family and domain databases
InterPro	IPR001650. Helicase_C. [Graphical view]
Pfam	PF00271. Helicase_C. 1 hit. [Graphical view]
PROSITE	PS51194. HELICASE_CTER. False negative. [Graphical view]
ProtoNet	Search...
Other
NextBio	970597.

Entry information

Entry name

YB112_YEAST

Accession

Primary (citable) accession number: Q3E7Y4
Secondary accession number(s): D6VPP3

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 5, 2006
Last sequence update:	November 8, 2005
Last modified:	May 1, 2013
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program