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Q3E7X9

- RS28A_YEAST

UniProt

Q3E7X9 - RS28A_YEAST

Protein

40S ribosomal protein S28-A

Gene

RPS28A

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli
  1. Functioni

    GO - Molecular functioni

    1. structural constituent of ribosome Source: SGD

    GO - Biological processi

    1. cytoplasmic translation Source: SGD
    2. positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay Source: SGD
    3. rRNA export from nucleus Source: SGD

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Enzyme and pathway databases

    BioCyciYEAST:G3O-33683-MONOMER.
    ReactomeiREACT_188965. SRP-dependent cotranslational protein targeting to membrane.
    REACT_189050. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
    REACT_189183. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
    REACT_217188. Formation of a pool of free 40S subunits.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    40S ribosomal protein S28-A
    Alternative name(s):
    S33
    YS27
    Gene namesi
    Name:RPS28A
    Synonyms:RPS33, RPS33A
    Ordered Locus Names:YOR167C
    ORF Names:O3600
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome XV

    Organism-specific databases

    CYGDiYOR167c.
    SGDiS000005693. RPS28A.

    Subcellular locationi

    Cytoplasm 1 Publication

    GO - Cellular componenti

    1. cytosolic small ribosomal subunit Source: SGD

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 676740S ribosomal protein S28-APRO_0000136842Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei1 – 11N-acetylmethionine2 Publications

    Post-translational modificationi

    N-terminally acetylated by acetyltransferase NatB.2 Publications

    Keywords - PTMi

    Acetylation

    Proteomic databases

    MaxQBiQ3E7X9.
    PaxDbiQ3E7X9.
    PRIDEiQ3E7X9.

    Expressioni

    Gene expression databases

    GenevestigatoriQ3E7X9.

    Interactioni

    Subunit structurei

    Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S).1 Publication

    Protein-protein interaction databases

    BioGridi34563. 39 interactions.
    DIPiDIP-29384N.
    IntActiQ3E7X9. 1 interaction.
    MINTiMINT-390375.

    Structurei

    Secondary structure

    1
    67
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi8 – 2215
    Beta strandi25 – 3511
    Beta strandi39 – 435
    Beta strandi53 – 608

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1VW9electron microscopy6.10d1-67[»]
    1VWVelectron microscopy6.10d1-67[»]
    3IZBelectron microscopy-Y1-67[»]
    3O2ZX-ray4.00R1-67[»]
    3O30X-ray4.00R1-67[»]
    3U5CX-ray3.00c1-67[»]
    3U5GX-ray3.00c1-67[»]
    4BYLelectron microscopy4.3021-67[»]
    4BYTelectron microscopy6.6021-67[»]
    4CUYelectron microscopy3.70c5-67[»]
    ProteinModelPortaliQ3E7X9.
    SMRiQ3E7X9. Positions 5-67.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein S28e family.Curated

    Phylogenomic databases

    eggNOGiCOG2053.
    GeneTreeiENSGT00390000003580.
    HOGENOMiHOG000224552.
    KOiK02979.
    OMAiPVRTNDI.
    OrthoDBiEOG7NCVH3.

    Family and domain databases

    Gene3Di2.40.50.140. 1 hit.
    HAMAPiMF_00292. Ribosomal_S28e.
    InterProiIPR012340. NA-bd_OB-fold.
    IPR000289. Ribosomal_S28e.
    IPR028626. Ribosomal_S28e_CS.
    [Graphical view]
    PANTHERiPTHR10769. PTHR10769. 1 hit.
    PfamiPF01200. Ribosomal_S28e. 1 hit.
    [Graphical view]
    ProDomiPD005541. Ribosomal_S28e. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SUPFAMiSSF50249. SSF50249. 1 hit.
    PROSITEiPS00961. RIBOSOMAL_S28E. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q3E7X9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDNKTPVTLA KVIKVLGRTG SRGGVTQVRV EFLEDTSRTI VRNVKGPVRE   50
    NDILVLMESE REARRLR 67
    Length:67
    Mass (Da):7,592
    Last modified:November 8, 2005 - v1
    Checksum:iBA145824DEE8A641
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X00128 Genomic DNA. Translation: CAA24958.1.
    U55021 Genomic DNA. Translation: AAB47414.1.
    Z75075 Genomic DNA. Translation: CAA99373.1.
    AY692746 Genomic DNA. Translation: AAT92765.1.
    BK006948 Genomic DNA. Translation: DAA10941.1.
    PIRiA02750. R3BY33.
    RefSeqiNP_014810.1. NM_001183586.1.

    Genome annotation databases

    EnsemblFungiiYOR167C; YOR167C; YOR167C.
    GeneIDi854338.
    KEGGisce:YOR167C.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X00128 Genomic DNA. Translation: CAA24958.1 .
    U55021 Genomic DNA. Translation: AAB47414.1 .
    Z75075 Genomic DNA. Translation: CAA99373.1 .
    AY692746 Genomic DNA. Translation: AAT92765.1 .
    BK006948 Genomic DNA. Translation: DAA10941.1 .
    PIRi A02750. R3BY33.
    RefSeqi NP_014810.1. NM_001183586.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1VW9 electron microscopy 6.10 d 1-67 [» ]
    1VWV electron microscopy 6.10 d 1-67 [» ]
    3IZB electron microscopy - Y 1-67 [» ]
    3O2Z X-ray 4.00 R 1-67 [» ]
    3O30 X-ray 4.00 R 1-67 [» ]
    3U5C X-ray 3.00 c 1-67 [» ]
    3U5G X-ray 3.00 c 1-67 [» ]
    4BYL electron microscopy 4.30 2 1-67 [» ]
    4BYT electron microscopy 6.60 2 1-67 [» ]
    4CUY electron microscopy 3.70 c 5-67 [» ]
    ProteinModelPortali Q3E7X9.
    SMRi Q3E7X9. Positions 5-67.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 34563. 39 interactions.
    DIPi DIP-29384N.
    IntActi Q3E7X9. 1 interaction.
    MINTi MINT-390375.

    Proteomic databases

    MaxQBi Q3E7X9.
    PaxDbi Q3E7X9.
    PRIDEi Q3E7X9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YOR167C ; YOR167C ; YOR167C .
    GeneIDi 854338.
    KEGGi sce:YOR167C.

    Organism-specific databases

    CYGDi YOR167c.
    SGDi S000005693. RPS28A.

    Phylogenomic databases

    eggNOGi COG2053.
    GeneTreei ENSGT00390000003580.
    HOGENOMi HOG000224552.
    KOi K02979.
    OMAi PVRTNDI.
    OrthoDBi EOG7NCVH3.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-33683-MONOMER.
    Reactomei REACT_188965. SRP-dependent cotranslational protein targeting to membrane.
    REACT_189050. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
    REACT_189183. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
    REACT_217188. Formation of a pool of free 40S subunits.

    Miscellaneous databases

    NextBioi 976408.

    Gene expression databases

    Genevestigatori Q3E7X9.

    Family and domain databases

    Gene3Di 2.40.50.140. 1 hit.
    HAMAPi MF_00292. Ribosomal_S28e.
    InterProi IPR012340. NA-bd_OB-fold.
    IPR000289. Ribosomal_S28e.
    IPR028626. Ribosomal_S28e_CS.
    [Graphical view ]
    PANTHERi PTHR10769. PTHR10769. 1 hit.
    Pfami PF01200. Ribosomal_S28e. 1 hit.
    [Graphical view ]
    ProDomi PD005541. Ribosomal_S28e. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SUPFAMi SSF50249. SSF50249. 1 hit.
    PROSITEi PS00961. RIBOSOMAL_S28E. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. "Analysis of a 22,956 bp region on the right arm of Saccharomyces cerevisiae chromosome XV."
      Madania A., Poch O., Tarassov I.A., Winsor B., Martin R.P.
      Yeast 12:1563-1573(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: S288c / FY1678.
    3. "The nucleotide sequence of Saccharomyces cerevisiae chromosome XV."
      Dujon B., Albermann K., Aldea M., Alexandraki D., Ansorge W., Arino J., Benes V., Bohn C., Bolotin-Fukuhara M., Bordonne R., Boyer J., Camasses A., Casamayor A., Casas C., Cheret G., Cziepluch C., Daignan-Fornier B., Dang V.-D.
      , de Haan M., Delius H., Durand P., Fairhead C., Feldmann H., Gaillon L., Galisson F., Gamo F.-J., Gancedo C., Goffeau A., Goulding S.E., Grivell L.A., Habbig B., Hand N.J., Hani J., Hattenhorst U., Hebling U., Hernando Y., Herrero E., Heumann K., Hiesel R., Hilger F., Hofmann B., Hollenberg C.P., Hughes B., Jauniaux J.-C., Kalogeropoulos A., Katsoulou C., Kordes E., Lafuente M.J., Landt O., Louis E.J., Maarse A.C., Madania A., Mannhaupt G., Marck C., Martin R.P., Mewes H.-W., Michaux G., Paces V., Parle-McDermott A.G., Pearson B.M., Perrin A., Pettersson B., Poch O., Pohl T.M., Poirey R., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rechmann S., Schwager C., Schweizer M., Sor F., Sterky F., Tarassov I.A., Teodoru C., Tettelin H., Thierry A., Tobiasch E., Tzermia M., Uhlen M., Unseld M., Valens M., Vandenbol M., Vetter I., Vlcek C., Voet M., Volckaert G., Voss H., Wambutt R., Wedler H., Wiemann S., Winsor B., Wolfe K.H., Zollner A., Zumstein E., Kleine K.
      Nature 387:98-102(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    4. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    5. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    6. "The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae."
      Planta R.J., Mager W.H.
      Yeast 14:471-477(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NOMENCLATURE, SUBUNIT.
    7. "The action of N-terminal acetyltransferases on yeast ribosomal proteins."
      Arnold R.J., Polevoda B., Reilly J.P., Sherman F.
      J. Biol. Chem. 274:37035-37040(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: ACETYLATION AT MET-1 BY NATB.
    8. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    9. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
    10. Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiRS28A_YEAST
    AccessioniPrimary (citable) accession number: Q3E7X9
    Secondary accession number(s): D6W2M5, P02380
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 21, 1986
    Last sequence update: November 8, 2005
    Last modified: October 1, 2014
    This is version 76 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 94500 molecules/cell in log phase SD medium.1 Publication
    There are 2 genes for S28 in yeast.

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. Ribosomal proteins
      Ribosomal proteins families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families
    4. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    5. Yeast chromosome XV
      Yeast (Saccharomyces cerevisiae) chromosome XV: entries and gene names

    External Data

    Dasty 3