Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

60S ribosomal protein L11-B

Gene

RPL11B

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Binds to 5S ribosomal RNA.

GO - Molecular functioni

  • rRNA binding Source: UniProtKB-KW
  • structural constituent of ribosome Source: SGD

GO - Biological processi

  • cytoplasmic translation Source: SGD
  • ribosomal large subunit assembly Source: SGD
  • translation Source: GO_Central
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Enzyme and pathway databases

BioCyciYEAST:G3O-30797-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L11-B
Alternative name(s):
L16
RP39
YL22
Gene namesi
Name:RPL11B
Synonyms:RP39B, RPL16B
Ordered Locus Names:YGR085C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VII

Organism-specific databases

EuPathDBiFungiDB:YGR085C.
SGDiS000003317. RPL11B.

Subcellular locationi

  • Cytoplasm
  • Nucleus

  • Note: The SYO1/RPL11/RPL5 complex is transported into the nucleus by KAP104.

GO - Cellular componenti

  • cytosolic large ribosomal subunit Source: SGD
  • nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedCombined sources1 Publication
ChainiPRO_00001251052 – 17460S ribosomal protein L11-BAdd BLAST173

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylserineCombined sources1 Publication1
Modified residuei75N6,N6,N6-trimethyllysine1 Publication1

Post-translational modificationi

N-terminally acetylated by acetyltransferase NatA.1 Publication

Keywords - PTMi

Acetylation, Methylation

Proteomic databases

MaxQBiQ3E757.
PRIDEiQ3E757.

PTM databases

iPTMnetiQ3E757.

Interactioni

Subunit structurei

Component of the large ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S). Forms a heterotrimeric complex with RPL5 and SYO1. Interaction of this complex with KAP104 allows the nuclear import of the heterotrimer.1 Publication

Protein-protein interaction databases

BioGridi33327. 58 interactors.
DIPiDIP-29386N.
IntActiQ3E757. 19 interactors.
MINTiMINT-564941.

Structurei

Secondary structure

1174
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi14 – 21Combined sources8
Beta strandi25 – 27Combined sources3
Helixi28 – 41Combined sources14
Beta strandi46 – 48Combined sources3
Beta strandi55 – 57Combined sources3
Beta strandi66 – 71Combined sources6
Helixi74 – 86Combined sources13
Turni87 – 89Combined sources3
Beta strandi90 – 92Combined sources3
Beta strandi93 – 96Combined sources4
Beta strandi102 – 107Combined sources6
Helixi109 – 111Combined sources3
Turni118 – 120Combined sources3
Beta strandi125 – 131Combined sources7
Turni134 – 136Combined sources3
Helixi137 – 140Combined sources4
Beta strandi141 – 144Combined sources4
Helixi150 – 152Combined sources3
Helixi156 – 164Combined sources9
Turni165 – 167Combined sources3
Beta strandi170 – 172Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2NOQelectron microscopy7.30H7-171[»]
3J0Qelectron microscopy10.60k7-171[»]
4U3MX-ray3.00M1/m12-174[»]
4U3NX-ray3.20M1/m12-174[»]
4U3UX-ray2.90M1/m12-174[»]
4U4NX-ray3.10M1/m12-174[»]
4U4OX-ray3.60M1/m12-174[»]
4U4QX-ray3.00M1/m12-174[»]
4U4RX-ray2.80M1/m12-174[»]
4U4UX-ray3.00M1/m12-174[»]
4U4YX-ray3.20M1/m12-174[»]
4U4ZX-ray3.10M1/m12-174[»]
4U50X-ray3.20M1/m12-174[»]
4U51X-ray3.20M1/m12-174[»]
4U52X-ray3.00M1/m12-174[»]
4U53X-ray3.30M1/m12-174[»]
4U55X-ray3.20M1/m12-174[»]
4U56X-ray3.45M1/m12-174[»]
4U6FX-ray3.10M1/m12-174[»]
4V8Telectron microscopy8.10J1-174[»]
5DATX-ray3.15M1/m12-174[»]
5DC3X-ray3.25M1/m12-174[»]
5I4LX-ray3.10M1/m16-174[»]
ProteinModelPortaliQ3E757.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ3E757.

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L5P family.Curated

Phylogenomic databases

HOGENOMiHOG000231312.
InParanoidiQ3E757.
KOiK02868.
OMAiWRRIKEN.
OrthoDBiEOG092C53PI.

Family and domain databases

Gene3Di3.30.1440.10. 1 hit.
InterProiIPR002132. Ribosomal_L5.
IPR031309. Ribosomal_L5_C.
IPR020929. Ribosomal_L5_CS.
IPR022803. Ribosomal_L5_domain.
IPR031310. Ribosomal_L5_N.
[Graphical view]
PfamiPF00281. Ribosomal_L5. 1 hit.
PF00673. Ribosomal_L5_C. 1 hit.
[Graphical view]
PIRSFiPIRSF002161. Ribosomal_L5. 1 hit.
SUPFAMiSSF55282. SSF55282. 1 hit.
PROSITEiPS00358. RIBOSOMAL_L5. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q3E757-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTKAQNPMR DLKIEKLVLN ISVGESGDRL TRASKVLEQL SGQTPVQSKA
60 70 80 90 100
RYTVRTFGIR RNEKIAVHVT VRGPKAEEIL ERGLKVKEYQ LRDRNFSATG
110 120 130 140 150
NFGFGIDEHI DLGIKYDPSI GIFGMDFYVV MNRPGARVTR RKRCKGTVGN
160 170
SHKTTKEDTV SWFKQKYDAD VLDK
Length:174
Mass (Da):19,750
Last modified:January 23, 2007 - v3
Checksum:i04F6CD88FEBD63E4
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti138V → A (PubMed:6390341).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z72870 Genomic DNA. Translation: CAA97087.1.
M12933 Genomic DNA. Translation: AAA34990.1.
BK006941 Genomic DNA. Translation: DAA08178.1.
PIRiA02764. R5BY16.
RefSeqiNP_011599.1. NM_001181214.1.

Genome annotation databases

EnsemblFungiiYGR085C; YGR085C; YGR085C.
GeneIDi852976.
KEGGisce:YGR085C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z72870 Genomic DNA. Translation: CAA97087.1.
M12933 Genomic DNA. Translation: AAA34990.1.
BK006941 Genomic DNA. Translation: DAA08178.1.
PIRiA02764. R5BY16.
RefSeqiNP_011599.1. NM_001181214.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2NOQelectron microscopy7.30H7-171[»]
3J0Qelectron microscopy10.60k7-171[»]
4U3MX-ray3.00M1/m12-174[»]
4U3NX-ray3.20M1/m12-174[»]
4U3UX-ray2.90M1/m12-174[»]
4U4NX-ray3.10M1/m12-174[»]
4U4OX-ray3.60M1/m12-174[»]
4U4QX-ray3.00M1/m12-174[»]
4U4RX-ray2.80M1/m12-174[»]
4U4UX-ray3.00M1/m12-174[»]
4U4YX-ray3.20M1/m12-174[»]
4U4ZX-ray3.10M1/m12-174[»]
4U50X-ray3.20M1/m12-174[»]
4U51X-ray3.20M1/m12-174[»]
4U52X-ray3.00M1/m12-174[»]
4U53X-ray3.30M1/m12-174[»]
4U55X-ray3.20M1/m12-174[»]
4U56X-ray3.45M1/m12-174[»]
4U6FX-ray3.10M1/m12-174[»]
4V8Telectron microscopy8.10J1-174[»]
5DATX-ray3.15M1/m12-174[»]
5DC3X-ray3.25M1/m12-174[»]
5I4LX-ray3.10M1/m16-174[»]
ProteinModelPortaliQ3E757.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi33327. 58 interactors.
DIPiDIP-29386N.
IntActiQ3E757. 19 interactors.
MINTiMINT-564941.

PTM databases

iPTMnetiQ3E757.

Proteomic databases

MaxQBiQ3E757.
PRIDEiQ3E757.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYGR085C; YGR085C; YGR085C.
GeneIDi852976.
KEGGisce:YGR085C.

Organism-specific databases

EuPathDBiFungiDB:YGR085C.
SGDiS000003317. RPL11B.

Phylogenomic databases

HOGENOMiHOG000231312.
InParanoidiQ3E757.
KOiK02868.
OMAiWRRIKEN.
OrthoDBiEOG092C53PI.

Enzyme and pathway databases

BioCyciYEAST:G3O-30797-MONOMER.

Miscellaneous databases

EvolutionaryTraceiQ3E757.
PROiQ3E757.

Family and domain databases

Gene3Di3.30.1440.10. 1 hit.
InterProiIPR002132. Ribosomal_L5.
IPR031309. Ribosomal_L5_C.
IPR020929. Ribosomal_L5_CS.
IPR022803. Ribosomal_L5_domain.
IPR031310. Ribosomal_L5_N.
[Graphical view]
PfamiPF00281. Ribosomal_L5. 1 hit.
PF00673. Ribosomal_L5_C. 1 hit.
[Graphical view]
PIRSFiPIRSF002161. Ribosomal_L5. 1 hit.
SUPFAMiSSF55282. SSF55282. 1 hit.
PROSITEiPS00358. RIBOSOMAL_L5. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRL11B_YEAST
AccessioniPrimary (citable) accession number: Q3E757
Secondary accession number(s): D6VUL7, P06380
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 1, 1988
Last sequence update: January 23, 2007
Last modified: November 2, 2016
This is version 108 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 21200 molecules/cell in log phase SD medium.1 Publication
There are 2 genes for L11 in yeast.

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families
  4. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  5. Yeast chromosome VII
    Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.