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Q3BZ95 (UPPP_XANC5) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Synonyms:bacA
Ordered Locus Names:XCV0187
OrganismXanthomonas campestris pv. vesicatoria (strain 85-10) [Complete proteome] [HAMAP]
Taxonomic identifier316273 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas

Protein attributes

Sequence length265 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 265265Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000227648

Regions

Transmembrane38 – 5821Helical; Potential
Transmembrane75 – 9521Helical; Potential
Transmembrane108 – 12821Helical; Potential
Transmembrane135 – 15521Helical; Potential
Transmembrane181 – 20121Helical; Potential
Transmembrane215 – 23521Helical; Potential
Transmembrane244 – 26421Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q3BZ95 [UniParc].

Last modified November 22, 2005. Version 1.
Checksum: A74E15DBE7F74BC0

FASTA26528,524
        10         20         30         40         50         60 
MSDLISALLL GILEGLTEFL PISSTGHLLI AEQWLGRRSD FFNIVIQAGA ILAICLALRQ 

        70         80         90        100        110        120 
RLWSLATGLG ERANRDYVLK VGVAFLVTAV VGLIVRKAGW QLPETLQPVA WALLIGGVWM 

       130        140        150        160        170        180 
LVAEHFAGKL PERDVVTWKV AIAVGLAQVV AGVFPGTSRS ASTIFIAMLL GLSKRSAAAD 

       190        200        210        220        230        240 
FVFMVGIPTM FAASGYALLE MYKEGGFGTE NWTDVAVAFV AATITGFVVV KWLLGYIKKH 

       250        260 
RFTVFAVYRM LLGAALLLWL PAAAG 

« Hide

References

[1]"Insights into genome plasticity and pathogenicity of the plant pathogenic Bacterium Xanthomonas campestris pv. vesicatoria revealed by the complete genome sequence."
Thieme F., Koebnik R., Bekel T., Berger C., Boch J., Buettner D., Caldana C., Gaigalat L., Goesmann A., Kay S., Kirchner O., Lanz C., Linke B., McHardy A.C., Meyer F., Mittenhuber G., Nies D.H., Niesbach-Kloesgen U. expand/collapse author list , Patschkowski T., Rueckert C., Rupp O., Schneiker S., Schuster S.C., Vorhoelter F.J., Weber E., Puehler A., Bonas U., Bartels D., Kaiser O.
J. Bacteriol. 187:7254-7266(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 85-10.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM039952 Genomic DNA. Translation: CAJ21818.1.
RefSeqYP_361918.1. NC_007508.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING316273.XCV0187.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAJ21818; CAJ21818; XCV0187.
GeneID3729791.
KEGGxcv:XCV0187.
PATRIC24089738. VBIXanCam71633_0384.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218356.
KOK06153.
OMAAQCFALI.
OrthoDBEOG6QP13M.
ProtClustDBPRK00281.

Enzyme and pathway databases

BioCycXCAM316273:GJF8-190-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUPPP_XANC5
AccessionPrimary (citable) accession number: Q3BZ95
Entry history
Integrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: November 22, 2005
Last modified: February 19, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families