Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Undecaprenyl-diphosphatase

Gene

uppP

Organism
Xanthomonas campestris pv. vesicatoria (strain 85-10)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.UniRule annotation

Catalytic activityi

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Antibiotic resistance, Cell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

Enzyme and pathway databases

BioCyciXCAM316273:GJF8-190-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Undecaprenyl-diphosphataseUniRule annotation (EC:3.6.1.27UniRule annotation)
Alternative name(s):
Bacitracin resistance proteinUniRule annotation
Undecaprenyl pyrophosphate phosphataseUniRule annotation
Gene namesi
Name:uppPUniRule annotation
Synonyms:bacA
Ordered Locus Names:XCV0187
OrganismiXanthomonas campestris pv. vesicatoria (strain 85-10)
Taxonomic identifieri316273 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
ProteomesiUP000007069 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei38 – 5821HelicalUniRule annotationAdd
BLAST
Transmembranei75 – 9521HelicalUniRule annotationAdd
BLAST
Transmembranei108 – 12821HelicalUniRule annotationAdd
BLAST
Transmembranei135 – 15521HelicalUniRule annotationAdd
BLAST
Transmembranei181 – 20121HelicalUniRule annotationAdd
BLAST
Transmembranei215 – 23521HelicalUniRule annotationAdd
BLAST
Transmembranei244 – 26421HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 265265Undecaprenyl-diphosphatasePRO_0000227648Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi316273.XCV0187.

Family & Domainsi

Sequence similaritiesi

Belongs to the UppP family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1968.
HOGENOMiHOG000218356.
KOiK06153.
OMAiAQCFALI.
OrthoDBiEOG6QP13M.

Family and domain databases

HAMAPiMF_01006. Undec_diphosphatase.
InterProiIPR003824. UppP.
[Graphical view]
PfamiPF02673. BacA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3BZ95-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDLISALLL GILEGLTEFL PISSTGHLLI AEQWLGRRSD FFNIVIQAGA
60 70 80 90 100
ILAICLALRQ RLWSLATGLG ERANRDYVLK VGVAFLVTAV VGLIVRKAGW
110 120 130 140 150
QLPETLQPVA WALLIGGVWM LVAEHFAGKL PERDVVTWKV AIAVGLAQVV
160 170 180 190 200
AGVFPGTSRS ASTIFIAMLL GLSKRSAAAD FVFMVGIPTM FAASGYALLE
210 220 230 240 250
MYKEGGFGTE NWTDVAVAFV AATITGFVVV KWLLGYIKKH RFTVFAVYRM
260
LLGAALLLWL PAAAG
Length:265
Mass (Da):28,524
Last modified:November 22, 2005 - v1
Checksum:iA74E15DBE7F74BC0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM039952 Genomic DNA. Translation: CAJ21818.1.
RefSeqiWP_007968085.1. NC_007508.1.
YP_361918.1. NC_007508.1.

Genome annotation databases

EnsemblBacteriaiCAJ21818; CAJ21818; XCV0187.
KEGGixcv:XCV0187.
PATRICi24089738. VBIXanCam71633_0384.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM039952 Genomic DNA. Translation: CAJ21818.1.
RefSeqiWP_007968085.1. NC_007508.1.
YP_361918.1. NC_007508.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi316273.XCV0187.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAJ21818; CAJ21818; XCV0187.
KEGGixcv:XCV0187.
PATRICi24089738. VBIXanCam71633_0384.

Phylogenomic databases

eggNOGiCOG1968.
HOGENOMiHOG000218356.
KOiK06153.
OMAiAQCFALI.
OrthoDBiEOG6QP13M.

Enzyme and pathway databases

BioCyciXCAM316273:GJF8-190-MONOMER.

Family and domain databases

HAMAPiMF_01006. Undec_diphosphatase.
InterProiIPR003824. UppP.
[Graphical view]
PfamiPF02673. BacA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 85-10.

Entry informationi

Entry nameiUPPP_XANC5
AccessioniPrimary (citable) accession number: Q3BZ95
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: November 22, 2005
Last modified: May 27, 2015
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.