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Q3BXK8

- BETA_XANC5

UniProt

Q3BXK8 - BETA_XANC5

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Protein
Oxygen-dependent choline dehydrogenase
Gene
betA, XCV0774
Organism
Xanthomonas campestris pv. vesicatoria (strain 85-10)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate By similarity.UniRule annotation

Catalytic activityi

Choline + acceptor = betaine aldehyde + reduced acceptor.UniRule annotation
Betaine aldehyde + NAD+ + H2O = betaine + NADH.UniRule annotation

Cofactori

FAD By similarity.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei475 – 4751 By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi6 – 3530FAD By similarity
Add
BLAST

GO - Molecular functioni

  1. betaine-aldehyde dehydrogenase activity Source: UniProtKB-EC
  2. choline dehydrogenase activity Source: UniProtKB-HAMAP
  3. flavin adenine dinucleotide binding Source: InterPro

GO - Biological processi

  1. glycine betaine biosynthetic process from choline Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

FAD, Flavoprotein, NAD

Enzyme and pathway databases

BioCyciXCAM316273:GJF8-789-MONOMER.
UniPathwayiUPA00529; UER00385.

Names & Taxonomyi

Protein namesi
Recommended name:
Oxygen-dependent choline dehydrogenase (EC:1.1.99.1)
Short name:
CDH
Short name:
CHD
Alternative name(s):
Betaine aldehyde dehydrogenase (EC:1.2.1.8)
Short name:
BADH
Gene namesi
Name:betA
Ordered Locus Names:XCV0774
OrganismiXanthomonas campestris pv. vesicatoria (strain 85-10)
Taxonomic identifieri316273 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
ProteomesiUP000007069: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 556556Oxygen-dependent choline dehydrogenaseUniRule annotation
PRO_0000258938Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi316273.XCV0774.

Structurei

3D structure databases

ProteinModelPortaliQ3BXK8.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG2303.
HOGENOMiHOG000139600.
KOiK00108.
OMAiYLQYACT.
OrthoDBiEOG67HJQP.

Family and domain databases

HAMAPiMF_00750. Choline_dehydrogen.
InterProiIPR011533. BetA.
IPR012132. GMC_OxRdtase.
IPR000172. GMC_OxRdtase_N.
IPR007867. GMC_OxRtase_C.
[Graphical view]
PfamiPF05199. GMC_oxred_C. 1 hit.
PF00732. GMC_oxred_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000137. Alcohol_oxidase. 1 hit.
TIGRFAMsiTIGR01810. betA. 1 hit.
PROSITEiPS00623. GMC_OXRED_1. 1 hit.
PS00624. GMC_OXRED_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3BXK8-1 [UniParc]FASTAAdd to Basket

« Hide

MQREYDYIII GAGSAGNVLA ARLTEDPGVT VLLLEAGGPD YRLDFRTQMP    50
AALAFPLQGR RYNWAYETEP EPYMDNRRME CGRGKGLGGS SLINGMCYIR 100
GNALDFDHWA KRPGLEDWSY RDVLPYFRKA ETRDIGANDY HGGDGPVSVA 150
TPKNDNNVLF HAMVEAGVQA GYPRTDDLNG YQQEGFGPMD RTVTPRGRRA 200
STARGYLDMA KPRDGLHIVT HATTDRILFA GKRAIGVHYL VGNSSEGIDA 250
HARREVLVCA GAIASPQLLQ RSGVGAPDLL RALDVQLVHD LPGVGQNLQD 300
HLEVYIQYAC TKPVSLYPAL QWWNQPAIGA EWLFAGTGTG ASNQFEAGGF 350
IRTREEFDWP NIQYHFLPVA INYNGSNAVK EHGFQAHVGS MRTPSRGRVH 400
AKSRDPRQHP SILFNYQSTD QDWQEFRDAI RITREIIAQP ALDPYRGREI 450
SPSADCKTDA ELDAFVRSRA ETAYHPSCSC AMGTDDMAVV DGQGRVHGME 500
GLRVIDASIM PRIITGNLNA TTIMIAEKIA DRMRGRPPLP RSTADYYIAG 550
DAPVRG 556
Length:556
Mass (Da):61,437
Last modified:November 22, 2005 - v1
Checksum:i0950ACBCC7F4392A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM039952 Genomic DNA. Translation: CAJ22405.1.
RefSeqiWP_011346382.1. NC_007508.1.
YP_362505.1. NC_007508.1.

Genome annotation databases

EnsemblBacteriaiCAJ22405; CAJ22405; XCV0774.
GeneIDi3729799.
KEGGixcv:XCV0774.
PATRICi24090926. VBIXanCam71633_0975.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM039952 Genomic DNA. Translation: CAJ22405.1 .
RefSeqi WP_011346382.1. NC_007508.1.
YP_362505.1. NC_007508.1.

3D structure databases

ProteinModelPortali Q3BXK8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 316273.XCV0774.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAJ22405 ; CAJ22405 ; XCV0774 .
GeneIDi 3729799.
KEGGi xcv:XCV0774.
PATRICi 24090926. VBIXanCam71633_0975.

Phylogenomic databases

eggNOGi COG2303.
HOGENOMi HOG000139600.
KOi K00108.
OMAi YLQYACT.
OrthoDBi EOG67HJQP.

Enzyme and pathway databases

UniPathwayi UPA00529 ; UER00385 .
BioCyci XCAM316273:GJF8-789-MONOMER.

Family and domain databases

HAMAPi MF_00750. Choline_dehydrogen.
InterProi IPR011533. BetA.
IPR012132. GMC_OxRdtase.
IPR000172. GMC_OxRdtase_N.
IPR007867. GMC_OxRtase_C.
[Graphical view ]
Pfami PF05199. GMC_oxred_C. 1 hit.
PF00732. GMC_oxred_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000137. Alcohol_oxidase. 1 hit.
TIGRFAMsi TIGR01810. betA. 1 hit.
PROSITEi PS00623. GMC_OXRED_1. 1 hit.
PS00624. GMC_OXRED_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 85-10.

Entry informationi

Entry nameiBETA_XANC5
AccessioniPrimary (citable) accession number: Q3BXK8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: November 22, 2005
Last modified: September 3, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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