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Protein

Glutamine--tRNA ligase

Gene

glnS

Organism
Xanthomonas campestris pv. vesicatoria (strain 85-10)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei74L-glutamine1
Binding sitei218L-glutamine1
Binding sitei237ATP1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi42 – 44ATP3
Nucleotide bindingi48 – 54ATP7
Nucleotide bindingi285 – 286ATP2
Nucleotide bindingi293 – 295ATP3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--tRNA ligase (EC:6.1.1.18)
Alternative name(s):
Glutaminyl-tRNA synthetase
Short name:
GlnRS
Gene namesi
Name:glnS
Ordered Locus Names:XCV0930
OrganismiXanthomonas campestris pv. vesicatoria (strain 85-10)
Taxonomic identifieri316273 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
Proteomesi
  • UP000007069 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002428811 – 579Glutamine--tRNA ligaseAdd BLAST579

Interactioni

Subunit structurei

Monomer.

Protein-protein interaction databases

STRINGi316273.XCV0930.

Structurei

3D structure databases

ProteinModelPortaliQ3BX52.
SMRiQ3BX52.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi41 – 51"HIGH" regionAdd BLAST11
Motifi292 – 296"KMSKS" region5

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.

Phylogenomic databases

eggNOGiENOG4105CX6. Bacteria.
COG0008. LUCA.
HOGENOMiHOG000259232.
KOiK01886.
OMAiVTHSICT.
OrthoDBiPOG091H00G9.

Family and domain databases

Gene3Di1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
HAMAPiMF_00126. Gln_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_N.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
PfamiView protein in Pfam
PF00749. tRNA-synt_1c. 2 hits.
PF03950. tRNA-synt_1c_C. 1 hit.
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF50715. SSF50715. 1 hit.
TIGRFAMsiTIGR00440. glnS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3BX52-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSETLATDAT APAEKKDFIR QIVREDLASG KHTVIRTRFP PEPNGYLHIG
60 70 80 90 100
HAKAICLDFG LAAEFGGLCN LRLDDTNPAK EDPEFVVAIQ DDVRWLGYEW
110 120 130 140 150
AQLRHASDYF QVYYLAAQKL IRDGHAFVCD LSAEQVRQYR GTLTEPGRNS
160 170 180 190 200
PFRERSVEEN LELFARMRAG EFPDGARTLR AKIDMASGNI NLRDPALYRI
210 220 230 240 250
KHVEHQNTGN AWPIYPMYDF AHSLGDAVEG ITHSLCTLEF EDHRPLYDWC
260 270 280 290 300
VDKVDLAGHP ELLQPLLDKG LPREAAKPRQ IEFSRLNINY TVMSKRKLTA
310 320 330 340 350
LVEEQLVDGW DDPRMYTLQG LRRRGYTPAA MRLFVDRVGI SKQNSLIDFS
360 370 380 390 400
VLEGCLREDL DAAAPRRMAV IDPLKLVLTN LPEGHTETLQ FSNHPKDESF
410 420 430 440 450
GTREVPFARE LWIEREDFAE VPPKGWKRLV PGGEIRLRGA GIARVDEVIK
460 470 480 490 500
NADGEIVELR GWLDPESRPG MEGANRKVKG TIHWVSAVHA VEAEIRLYDR
510 520 530 540 550
LFSVEKPDDE SEGKTYRDYL NPESKRNVRG YVEPSAAMAA PEQAFQFERS
560 570
GYFVADRRDH SAATPVFNRS VTLRDTWAK
Length:579
Mass (Da):65,842
Last modified:November 22, 2005 - v1
Checksum:i430E1CA0B79E452D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM039952 Genomic DNA. Translation: CAJ22561.1.
RefSeqiWP_011346499.1. NZ_CP017190.1.

Genome annotation databases

EnsemblBacteriaiCAJ22561; CAJ22561; XCV0930.
KEGGixcv:XCV0930.

Similar proteinsi

Entry informationi

Entry nameiSYQ_XANC5
AccessioniPrimary (citable) accession number: Q3BX52
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: November 22, 2005
Last modified: November 22, 2017
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families