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Q3BW89

- GCSP_XANC5

UniProt

Q3BW89 - GCSP_XANC5

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Protein
Glycine dehydrogenase (decarboxylating)
Gene
gcvP, XCV1243
Organism
Xanthomonas campestris pv. vesicatoria (strain 85-10)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO2 is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein By similarity.UniRule annotation

Catalytic activityi

Glycine + [glycine-cleavage complex H protein]-N(6)-lipoyl-L-lysine = [glycine-cleavage complex H protein]-S-aminomethyl-N(6)-dihydrolipoyl-L-lysine + CO2.UniRule annotation

Cofactori

Pyridoxal phosphate By similarity.UniRule annotation

GO - Molecular functioni

  1. glycine dehydrogenase (decarboxylating) activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. glycine decarboxylation via glycine cleavage system Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

Pyridoxal phosphate

Enzyme and pathway databases

BioCyciXCAM316273:GJF8-1278-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycine dehydrogenase (decarboxylating) (EC:1.4.4.2)
Alternative name(s):
Glycine cleavage system P-protein
Glycine decarboxylase
Glycine dehydrogenase (aminomethyl-transferring)
Gene namesi
Name:gcvP
Ordered Locus Names:XCV1243
OrganismiXanthomonas campestris pv. vesicatoria (strain 85-10)
Taxonomic identifieri316273 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
ProteomesiUP000007069: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 954954Glycine dehydrogenase (decarboxylating)UniRule annotation
PRO_1000045626Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei702 – 7021N6-(pyridoxal phosphate)lysine By similarity

Interactioni

Subunit structurei

The glycine cleavage system is composed of four proteins: P, T, L and H By similarity.

Protein-protein interaction databases

STRINGi316273.XCV1243.

Structurei

3D structure databases

ProteinModelPortaliQ3BW89.

Family & Domainsi

Sequence similaritiesi

Belongs to the GcvP family.

Phylogenomic databases

eggNOGiCOG1003.
HOGENOMiHOG000239369.
KOiK00281.
OMAiAELMPVS.
OrthoDBiEOG6HMXDX.

Family and domain databases

Gene3Di3.40.640.10. 2 hits.
HAMAPiMF_00711. GcvP.
InterProiIPR020580. GDC-P_N.
IPR020581. GDC_P.
IPR003437. GDC_P_homo.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11773. PTHR11773. 1 hit.
PfamiPF02347. GDC-P. 2 hits.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 3 hits.
TIGRFAMsiTIGR00461. gcvP. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3BW89-1 [UniParc]FASTAAdd to Basket

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MSQTPSSLRD LEHHSAFVER HIGPNDAEIA QMLDVVGHAC LDALTDAIVP    50
GNIKSPAPLA LPEAITEEEA LAKIRAIADK NTVFRNFIGQ GYYGTHTPKV 100
ILRNILENPA WYTAYTPYQA EISQGRMEAL INFQTLCADL TGMQIANASL 150
LDEATAAAEA MTLAKRSAKS RSNTFFVHDA VHPQTLELLR TRAEPLDIVL 200
RVGTPEEALQ AECFGVLLQY PDSFGHIGDH AALADAVHAQ GGLVAVATDL 250
LALTLIAAPG EWGADIVVGN SQRFGVPFGF GGPHAAFMAC RDAYKRSMPG 300
RLIGVSIDAA GNPAYRLTLQ TREQHIRREK ATSNICTAQV LLAVMASMYA 350
VYHGPDGLTR IARRTHRLAA ILAAALRSAG VTVGERFFDT LHVKAIDANA 400
IHARARAAGI NLRAIDSEAV GISLDETSTR ADVVALAALF GAQADVDALD 450
AATADALPQG LLRTTPFLTH PVFNTHHSEH ELLRYMRSLA DKDLAMDRTM 500
IPLGSCTMKL NATAEMIPVT WPEFGAIHPL APAEQSAGYA QLIDELEAML 550
VECTGYDAVS LQPNSGAQGE YAGLLAIRAY HRSRGEAHRD ICLIPESAHG 600
TNPASAQMCG MTVVVTKCDA NGNVDVDDIR AKAEKYSDRL AALMITYPST 650
HGVFEEDVVA ICEAVHAHGG QVYTDGANMN ALVGVAKPGK WGSDVSHLNL 700
HKTFCIPHGG GGPGVGPCAV KSHLAPYLPK TLGGEGDVGM VSAASYGSAS 750
ILPISWMYVT MMGSAGLRKA TQVALLNANY IAKRLAPHYK TLYTGRNGLV 800
AHECILDVRP LEKTSGIGAE DIAKRLIDFG FHAPTLSFPV AGTLMVEPTE 850
SESQHELDRF IDAMIQIREE IRAIEDGRLD REDNPLKHAP HTATQVSASE 900
WTHAYPRELA AFPLPSLKQQ KYWPPVARVD NVYGDKNVMC ACIPVDAYKE 950
DVEA 954
Length:954
Mass (Da):102,578
Last modified:November 22, 2005 - v1
Checksum:i17303C000C2FAECC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM039952 Genomic DNA. Translation: CAJ22874.1.
RefSeqiWP_011346720.1. NC_007508.1.
YP_362974.1. NC_007508.1.

Genome annotation databases

EnsemblBacteriaiCAJ22874; CAJ22874; XCV1243.
GeneIDi3730132.
KEGGixcv:XCV1243.
PATRICi24091936. VBIXanCam71633_1464.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM039952 Genomic DNA. Translation: CAJ22874.1 .
RefSeqi WP_011346720.1. NC_007508.1.
YP_362974.1. NC_007508.1.

3D structure databases

ProteinModelPortali Q3BW89.
ModBasei Search...

Protein-protein interaction databases

STRINGi 316273.XCV1243.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAJ22874 ; CAJ22874 ; XCV1243 .
GeneIDi 3730132.
KEGGi xcv:XCV1243.
PATRICi 24091936. VBIXanCam71633_1464.

Phylogenomic databases

eggNOGi COG1003.
HOGENOMi HOG000239369.
KOi K00281.
OMAi AELMPVS.
OrthoDBi EOG6HMXDX.

Enzyme and pathway databases

BioCyci XCAM316273:GJF8-1278-MONOMER.

Family and domain databases

Gene3Di 3.40.640.10. 2 hits.
HAMAPi MF_00711. GcvP.
InterProi IPR020580. GDC-P_N.
IPR020581. GDC_P.
IPR003437. GDC_P_homo.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view ]
PANTHERi PTHR11773. PTHR11773. 1 hit.
Pfami PF02347. GDC-P. 2 hits.
[Graphical view ]
SUPFAMi SSF53383. SSF53383. 3 hits.
TIGRFAMsi TIGR00461. gcvP. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 85-10.

Entry informationi

Entry nameiGCSP_XANC5
AccessioniPrimary (citable) accession number: Q3BW89
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 22, 2005
Last modified: September 3, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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