Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Beta-hexosaminidase

Gene

nagZ

Organism
Xanthomonas campestris pv. vesicatoria (strain 85-10)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Protein inferred from homologyi

Functioni

Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.UniRule annotation

Catalytic activityi

Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.UniRule annotation

Pathwayi: peptidoglycan recycling

This protein is involved in the pathway peptidoglycan recycling, which is part of Cell wall biogenesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan recycling and in Cell wall biogenesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei60SubstrateUniRule annotation1
Binding sitei68SubstrateUniRule annotation1
Binding sitei133SubstrateUniRule annotation1
Sitei174Important for catalytic activityUniRule annotation1
Active sitei176Proton donor/acceptorUniRule annotation1
Active sitei247NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase
Biological processCell cycle, Cell division, Cell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

Enzyme and pathway databases

UniPathwayiUPA00544.

Protein family/group databases

CAZyiGH3. Glycoside Hydrolase Family 3.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-hexosaminidaseUniRule annotation (EC:3.2.1.52UniRule annotation)
Alternative name(s):
Beta-N-acetylhexosaminidaseUniRule annotation
N-acetyl-beta-glucosaminidaseUniRule annotation
Gene namesi
Name:nagZUniRule annotation
Ordered Locus Names:XCV1386
OrganismiXanthomonas campestris pv. vesicatoria (strain 85-10)
Taxonomic identifieri316273 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
Proteomesi
  • UP000007069 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002349291 – 334Beta-hexosaminidaseAdd BLAST334

Interactioni

Protein-protein interaction databases

STRINGi316273.XCV1386.

Structurei

3D structure databases

ProteinModelPortaliQ3BVU6.
SMRiQ3BVU6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni163 – 164Substrate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QPA. Bacteria.
COG1472. LUCA.
HOGENOMiHOG000248526.
KOiK01207.
OrthoDBiPOG091H039J.

Family and domain databases

Gene3Di3.20.20.300. 1 hit.
HAMAPiMF_00364. NagZ. 1 hit.
InterProiView protein in InterPro
IPR022956. Beta_hexosaminidase_bac.
IPR019800. Glyco_hydro_3_AS.
IPR001764. Glyco_hydro_3_N.
IPR036962. Glyco_hydro_3_N_sf.
IPR017853. Glycoside_hydrolase_SF.
PfamiView protein in Pfam
PF00933. Glyco_hydro_3. 1 hit.
SUPFAMiSSF51445. SSF51445. 1 hit.
PROSITEiView protein in PROSITE
PS00775. GLYCOSYL_HYDROL_F3. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3BVU6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLIGVAGTE LSAQERDWLQ HDAVAGVVLF KRNFASRTQV AELSAAIRAA
60 70 80 90 100
APRPVLVCVD QEGGRVQRFR EGFSALAPLQ SFGAQYAHDP ESALAAARAH
110 120 130 140 150
AQLMASEVRA SGVDLSFAPV VDLGRGNRAI GDRAFSDDPQ IVATFTRAYV
160 170 180 190 200
QALHGAGMAA TLKHFPGHGT VLEDTHVDHA SDPRPLEVLQ AEDLVPFVAG
210 220 230 240 250
IEAGADAVMM AHVVYPQVAP EPAGYSQRWI EQILRGQMGF CGVVFSDDIG
260 270 280 290 300
MAASFSAGGV AGRVHAHLDA GCDVVLVCHP ELVAESLQAV QGRSLNTAAL
310 320 330
IGLIGRGALG WDGLLAGTDA SFTTPPSAHF GTTA
Length:334
Mass (Da):34,931
Last modified:May 16, 2006 - v2
Checksum:i7F81413243693110
GO

Sequence cautioni

The sequence CAJ23017 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM039952 Genomic DNA. Translation: CAJ23017.1. Different initiation.
RefSeqiWP_041855112.1. NZ_CP017190.1.

Genome annotation databases

EnsemblBacteriaiCAJ23017; CAJ23017; XCV1386.
KEGGixcv:XCV1386.

Similar proteinsi

Entry informationi

Entry nameiNAGZ_XANC5
AccessioniPrimary (citable) accession number: Q3BVU6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: May 16, 2006
Last modified: October 25, 2017
This is version 77 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families