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Q3BQX8

- PUR5_XANC5

UniProt

Q3BQX8 - PUR5_XANC5

Protein

Phosphoribosylformylglycinamidine cyclo-ligase

Gene

purM

Organism
Xanthomonas campestris pv. vesicatoria (strain 85-10)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 1 (22 Nov 2005)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Ligase

    Keywords - Biological processi

    Purine biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciXCAM316273:GJF8-3197-MONOMER.
    UniPathwayiUPA00074; UER00129.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotation (EC:6.3.3.1UniRule annotation)
    Alternative name(s):
    AIR synthaseUniRule annotation
    AIRSUniRule annotation
    Phosphoribosyl-aminoimidazole synthetaseUniRule annotation
    Gene namesi
    Name:purMUniRule annotation
    Ordered Locus Names:XCV3104
    OrganismiXanthomonas campestris pv. vesicatoria (strain 85-10)
    Taxonomic identifieri316273 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
    ProteomesiUP000007069: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 341341Phosphoribosylformylglycinamidine cyclo-ligasePRO_0000258430Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi316273.XCV3104.

    Structurei

    3D structure databases

    ProteinModelPortaliQ3BQX8.
    SMRiQ3BQX8. Positions 1-340.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the AIR synthase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0150.
    HOGENOMiHOG000229090.
    KOiK01933.
    OMAiEFEMYRT.
    OrthoDBiEOG61CM1V.

    Family and domain databases

    Gene3Di3.30.1330.10. 1 hit.
    3.90.650.10. 1 hit.
    HAMAPiMF_00741_B. AIRS_B.
    InterProiIPR010918. AIR_synth_C_dom.
    IPR000728. AIR_synth_N_dom.
    IPR004733. PurM_cligase.
    IPR016188. PurM_N-like.
    [Graphical view]
    PfamiPF00586. AIRS. 1 hit.
    PF02769. AIRS_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF55326. SSF55326. 1 hit.
    SSF56042. SSF56042. 1 hit.
    TIGRFAMsiTIGR00878. purM. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q3BQX8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTYRDAGVDI DAGNALVERI KPLVKRSFRP EVMGGLGGFG ALFDLSGKYK    50
    EPVLVSGTDG VGTKLKLAQQ LGRHDTIGID LVGMCVNDVL VQGAEPLFFL 100
    DYFATGKLDV DTAAAVVGGI ARGCELSGCA LIGGETAEMP DMYPPGEYDL 150
    AGFTVGAVEK SQLLDGAQVR DGDVLIGIAS SGPHSNGYSL IRKIYERAGA 200
    PAEHVLDDGT KLIDALMAPT ALYVKPVLSL LKSHGEAIHA MAHITGGGLT 250
    ENIIRVIPQG LGLDIDATAW TLPPVFAWLQ REGAVADAEM WRTFNCGIGF 300
    VLIASLEQAA TLEQALDAQS LAHWRIGQVV PAHGDERVRI G 341
    Length:341
    Mass (Da):35,987
    Last modified:November 22, 2005 - v1
    Checksum:iEDE150C95DE21DD1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM039952 Genomic DNA. Translation: CAJ24835.1.
    RefSeqiWP_011348138.1. NC_007508.1.
    YP_364835.1. NC_007508.1.

    Genome annotation databases

    EnsemblBacteriaiCAJ24835; CAJ24835; XCV3104.
    GeneIDi3732956.
    KEGGixcv:XCV3104.
    PATRICi24095802. VBIXanCam71633_3372.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM039952 Genomic DNA. Translation: CAJ24835.1 .
    RefSeqi WP_011348138.1. NC_007508.1.
    YP_364835.1. NC_007508.1.

    3D structure databases

    ProteinModelPortali Q3BQX8.
    SMRi Q3BQX8. Positions 1-340.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 316273.XCV3104.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAJ24835 ; CAJ24835 ; XCV3104 .
    GeneIDi 3732956.
    KEGGi xcv:XCV3104.
    PATRICi 24095802. VBIXanCam71633_3372.

    Phylogenomic databases

    eggNOGi COG0150.
    HOGENOMi HOG000229090.
    KOi K01933.
    OMAi EFEMYRT.
    OrthoDBi EOG61CM1V.

    Enzyme and pathway databases

    UniPathwayi UPA00074 ; UER00129 .
    BioCyci XCAM316273:GJF8-3197-MONOMER.

    Family and domain databases

    Gene3Di 3.30.1330.10. 1 hit.
    3.90.650.10. 1 hit.
    HAMAPi MF_00741_B. AIRS_B.
    InterProi IPR010918. AIR_synth_C_dom.
    IPR000728. AIR_synth_N_dom.
    IPR004733. PurM_cligase.
    IPR016188. PurM_N-like.
    [Graphical view ]
    Pfami PF00586. AIRS. 1 hit.
    PF02769. AIRS_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55326. SSF55326. 1 hit.
    SSF56042. SSF56042. 1 hit.
    TIGRFAMsi TIGR00878. purM. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 85-10.

    Entry informationi

    Entry nameiPUR5_XANC5
    AccessioniPrimary (citable) accession number: Q3BQX8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 31, 2006
    Last sequence update: November 22, 2005
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3