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Q3BQS1 (AROB_XANC5) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-dehydroquinate synthase
EC=4.2.3.4
Gene names
Name:aroB
Ordered Locus Names:XCV3161
OrganismXanthomonas campestris pv. vesicatoria (strain 85-10) [Complete proteome] [HAMAP]
Taxonomic identifier316273 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Xanthomonadales › Xanthomonadaceae › Xanthomonas

Protein attributes

Sequence length370 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

Divalent metal cations By similarity. HAMAP MF_00110

NAD By similarity. HAMAP MF_00110

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity. HAMAP MF_00110

Subcellular location

Cytoplasm Probable HAMAP MF_00110.

Sequence similarities

Belongs to the dehydroquinate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   LigandNAD
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3703703-dehydroquinate synthase HAMAP MF_00110
PRO_0000231144

Sequences

Sequence LengthMass (Da)Tools
Q3BQS1 [UniParc].

Last modified November 22, 2005. Version 1.
Checksum: 411BE37377247AE4

FASTA37038,864
        10         20         30         40         50         60 
MTLPRSSRSV DLDGVQPYTI TIAPGLLADG ARLAGHVRGR HALLLSDSQV APHYAAGVRT 

        70         80         90        100        110        120 
ALLNARPDLQ VGELVIAAGE ASKTLETFGS AITALAELGA TRDACVFALG GGVVGDLAGF 

       130        140        150        160        170        180 
AAACWMRGVD CVQLPTSLLA MVDSSVGGKT AVDIPQGKNL VGAFHPPRAV IADTDTLRTL 

       190        200        210        220        230        240 
PPRELRAGLA EVIKYGAIRD PLFFQWLHAE RRALLDGDAA ALAQAIARSC EHKAEIVARD 

       250        260        270        280        290        300 
PLEKGERALL NLGHTFGHAI ETEQGYGAPG NDNLNHGEAV AVGMVLAARL SAALGMSDAQ 

       310        320        330        340        350        360 
DTEALRTLLH DFDLPTEIPP GLTPQALLAR MRLDKKNIAG RLRLVLWRGI GKAEIVPDVE 

       370 
EAAVLEILAG

« Hide

References

[1]"Insights into genome plasticity and pathogenicity of the plant pathogenic Bacterium Xanthomonas campestris pv. vesicatoria revealed by the complete genome sequence."
Thieme F., Koebnik R., Bekel T., Berger C., Boch J., Buettner D., Caldana C., Gaigalat L., Goesmann A., Kay S., Kirchner O., Lanz C., Linke B., McHardy A.C., Meyer F., Mittenhuber G., Nies D.H., Niesbach-Kloesgen U. expand/collapse author list , Patschkowski T., Rueckert C., Rupp O., Schneiker S., Schuster S.C., Vorhoelter F.J., Weber E., Puehler A., Bonas U., Bartels D., Kaiser O.
J. Bacteriol. 187:7254-7266(2005) [PubMed: 16237009] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 85-10.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM039952 Genomic DNA. Translation: CAJ24892.1.
RefSeqYP_364892.1. NC_007508.1.

3D structure databases

ProteinModelPortalQ3BQS1.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ3BQS1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3733566.
GenomeReviewsGene locus XCV3161 in contig AM039952_GR.
KEGGxcv:XCV3161.
NMPDRfig|316273.3.peg.2778.
PATRIC24095924. VBIXanCam71633_3433.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0337.
HOGENOMHBG632303.
OMAVMALEMS.
ProtClustDBPRK00002.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
[Tree]
InterProIPR016037. DHQ_synth_AroB.
[Graphical view]
KOK01735.
PANTHERPTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. AroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAROB_XANC5
AccessionPrimary (citable) accession number: Q3BQS1
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: November 22, 2005
Last modified: January 25, 2012
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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