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Q3BPD5

- PNCB_XANC5

UniProt

Q3BPD5 - PNCB_XANC5

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Protein
Nicotinate phosphoribosyltransferase
Gene
pncB, XCV3647
Organism
Xanthomonas campestris pv. vesicatoria (strain 85-10)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity.UniRule annotation

Catalytic activityi

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ligase activity Source: UniProtKB-KW
  2. nicotinate phosphoribosyltransferase activity Source: InterPro
  3. nicotinate-nucleotide diphosphorylase (carboxylating) activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. NAD biosynthetic process Source: UniProtKB-UniPathway
  2. nicotinate nucleotide biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ligase, Transferase

Keywords - Biological processi

Pyridine nucleotide biosynthesis

Enzyme and pathway databases

BioCyciXCAM316273:GJF8-3750-MONOMER.
UniPathwayiUPA00253; UER00457.

Names & Taxonomyi

Protein namesi
Recommended name:
Nicotinate phosphoribosyltransferase (EC:6.3.4.21)
Short name:
NAPRTase
Gene namesi
Name:pncB
Ordered Locus Names:XCV3647
OrganismiXanthomonas campestris pv. vesicatoria (strain 85-10)
Taxonomic identifieri316273 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
ProteomesiUP000007069: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 392392Nicotinate phosphoribosyltransferaseUniRule annotation
PRO_1000025018Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi316273.XCV3647.

Structurei

3D structure databases

ProteinModelPortaliQ3BPD5.

Family & Domainsi

Sequence similaritiesi

Belongs to the NAPRTase family.

Phylogenomic databases

eggNOGiCOG1488.
HOGENOMiHOG000284929.
KOiK00763.
OMAiQAVFHRY.
OrthoDBiEOG6X10XB.

Family and domain databases

HAMAPiMF_00570. NAPRTase.
InterProiIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERiPTHR11098. PTHR11098. 1 hit.
PfamiPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFiPIRSF000484. NAPRT. 1 hit.
SUPFAMiSSF51690. SSF51690. 1 hit.
TIGRFAMsiTIGR01514. NAPRTase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3BPD5-1 [UniParc]FASTAAdd to Basket

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MIIHSLLDTD LYKFTMMQAV LHQHPAAQVD YRFKCRTPGV DLAQFVDEIS    50
REIDALCRLR LREDEVDYLR SLRFIKPDFA DFLALFHLDR KYLSLTASAT 100
HPGEIELTIR GPWLHTILFE VPLLAIINEV WFRNTSEPDF EEGRSRLREK 150
VASLRSMPAG CKIADYGTRR RYSRQWHGEL LPLLRDGLGE QFVGTSNVYF 200
AKQYGLTPLG TMAHEYLQAF QALGPRLRDS QVAALESWAR EYRGDLGIAL 250
SDVVGLDAFL RDFDLYFCKL FDGMRHDSGD PFEWGERVIA HLEAHRVDPR 300
TKVLVFSDGL NIDKVMRLYQ HFHTRCRLAF GVGTSLTNDL GPTPLQIVIK 350
MVRCNGQPVA KLSDSPGKSM CEDIGYLRYL RDVFGLPPMA EG 392
Length:392
Mass (Da):44,862
Last modified:November 22, 2005 - v1
Checksum:i463A6C59065876B4
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM039952 Genomic DNA. Translation: CAJ25378.1.
RefSeqiYP_365378.1. NC_007508.1.

Genome annotation databases

EnsemblBacteriaiCAJ25378; CAJ25378; XCV3647.
GeneIDi3733425.
KEGGixcv:XCV3647.
PATRICi24096918. VBIXanCam71633_3928.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM039952 Genomic DNA. Translation: CAJ25378.1 .
RefSeqi YP_365378.1. NC_007508.1.

3D structure databases

ProteinModelPortali Q3BPD5.
ModBasei Search...

Protein-protein interaction databases

STRINGi 316273.XCV3647.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAJ25378 ; CAJ25378 ; XCV3647 .
GeneIDi 3733425.
KEGGi xcv:XCV3647.
PATRICi 24096918. VBIXanCam71633_3928.

Phylogenomic databases

eggNOGi COG1488.
HOGENOMi HOG000284929.
KOi K00763.
OMAi QAVFHRY.
OrthoDBi EOG6X10XB.

Enzyme and pathway databases

UniPathwayi UPA00253 ; UER00457 .
BioCyci XCAM316273:GJF8-3750-MONOMER.

Family and domain databases

HAMAPi MF_00570. NAPRTase.
InterProi IPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view ]
PANTHERi PTHR11098. PTHR11098. 1 hit.
Pfami PF04095. NAPRTase. 1 hit.
[Graphical view ]
PIRSFi PIRSF000484. NAPRT. 1 hit.
SUPFAMi SSF51690. SSF51690. 1 hit.
TIGRFAMsi TIGR01514. NAPRTase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 85-10.

Entry informationi

Entry nameiPNCB_XANC5
AccessioniPrimary (citable) accession number: Q3BPD5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 22, 2005
Last modified: September 3, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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