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Q3BPD5 (PNCB_XANC5) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:XCV3647
OrganismXanthomonas campestris pv. vesicatoria (strain 85-10) [Complete proteome] [HAMAP]
Taxonomic identifier316273 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas

Protein attributes

Sequence length392 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 392392Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_1000025018

Sequences

Sequence LengthMass (Da)Tools
Q3BPD5 [UniParc].

Last modified November 22, 2005. Version 1.
Checksum: 463A6C59065876B4

FASTA39244,862
        10         20         30         40         50         60 
MIIHSLLDTD LYKFTMMQAV LHQHPAAQVD YRFKCRTPGV DLAQFVDEIS REIDALCRLR 

        70         80         90        100        110        120 
LREDEVDYLR SLRFIKPDFA DFLALFHLDR KYLSLTASAT HPGEIELTIR GPWLHTILFE 

       130        140        150        160        170        180 
VPLLAIINEV WFRNTSEPDF EEGRSRLREK VASLRSMPAG CKIADYGTRR RYSRQWHGEL 

       190        200        210        220        230        240 
LPLLRDGLGE QFVGTSNVYF AKQYGLTPLG TMAHEYLQAF QALGPRLRDS QVAALESWAR 

       250        260        270        280        290        300 
EYRGDLGIAL SDVVGLDAFL RDFDLYFCKL FDGMRHDSGD PFEWGERVIA HLEAHRVDPR 

       310        320        330        340        350        360 
TKVLVFSDGL NIDKVMRLYQ HFHTRCRLAF GVGTSLTNDL GPTPLQIVIK MVRCNGQPVA 

       370        380        390 
KLSDSPGKSM CEDIGYLRYL RDVFGLPPMA EG 

« Hide

References

[1]"Insights into genome plasticity and pathogenicity of the plant pathogenic Bacterium Xanthomonas campestris pv. vesicatoria revealed by the complete genome sequence."
Thieme F., Koebnik R., Bekel T., Berger C., Boch J., Buettner D., Caldana C., Gaigalat L., Goesmann A., Kay S., Kirchner O., Lanz C., Linke B., McHardy A.C., Meyer F., Mittenhuber G., Nies D.H., Niesbach-Kloesgen U. expand/collapse author list , Patschkowski T., Rueckert C., Rupp O., Schneiker S., Schuster S.C., Vorhoelter F.J., Weber E., Puehler A., Bonas U., Bartels D., Kaiser O.
J. Bacteriol. 187:7254-7266(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 85-10.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM039952 Genomic DNA. Translation: CAJ25378.1.
RefSeqYP_365378.1. NC_007508.1.

3D structure databases

ProteinModelPortalQ3BPD5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING316273.XCV3647.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAJ25378; CAJ25378; XCV3647.
GeneID3733425.
KEGGxcv:XCV3647.
PATRIC24096918. VBIXanCam71633_3928.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284929.
KOK00763.
OMAQAVFHRY.
OrthoDBEOG6X10XB.

Enzyme and pathway databases

BioCycXCAM316273:GJF8-3750-MONOMER.
UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_XANC5
AccessionPrimary (citable) accession number: Q3BPD5
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 22, 2005
Last modified: June 11, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways