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Protein

Xylose isomerase

Gene

xylA1

Organism
Xanthomonas campestris pv. vesicatoria (strain 85-10)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei109UniRule annotation1
Active sitei112UniRule annotation1
Metal bindingi240Magnesium 1UniRule annotation1
Metal bindingi276Magnesium 1UniRule annotation1
Metal bindingi276Magnesium 2UniRule annotation1
Metal bindingi279Magnesium 2UniRule annotation1
Metal bindingi304Magnesium 1UniRule annotation1
Metal bindingi315Magnesium 2UniRule annotation1
Metal bindingi317Magnesium 2UniRule annotation1
Metal bindingi347Magnesium 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Carbohydrate metabolism, Pentose shunt, Xylose metabolism

Keywords - Ligandi

Magnesium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylA1UniRule annotation
Ordered Locus Names:XCV1808, XCV4330
OrganismiXanthomonas campestris pv. vesicatoria (strain 85-10)
Taxonomic identifieri316273 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
Proteomesi
  • UP000007069 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002369771 – 445Xylose isomeraseAdd BLAST445

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi316273.XCV4330.

Structurei

3D structure databases

ProteinModelPortaliQ3BMF2.
SMRiQ3BMF2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C93. Bacteria.
COG2115. LUCA.
HOGENOMiHOG000252293.
KOiK01805.
OMAiHTFQHEL.
OrthoDBiPOG091H07LC.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A. 1 hit.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3BMF2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNTVYIGAK EYFPGIGKIG FEGRDSDNPL AFKVYDANKT IGDKTMAEHL
60 70 80 90 100
RFAVAYWHSF CGNGADPFGP GTRAYPWDAG TTALNRAEAK ADAAFEFFTK
110 120 130 140 150
LGVPYYCFHD IDLAPDADDI GEYEKNLKHM VGIAKQRQAD TGIKLLWGTA
160 170 180 190 200
NLFSHPRYMN GASTNPDFNV VARAAVQVKA AIDATVELGG ENYVFWGGRE
210 220 230 240 250
GYACLHNTQM KREQDNMARF LTLARDYGRA IGFKGNFLIE PKPMEPMKHQ
260 270 280 290 300
YDFDSATVIG FLRQHGLDQD FKLNIEANHA TLSGHSFEHD LQVASDAGLL
310 320 330 340 350
GSIDANRGNP QNGWDTDQFP TDLYDTVGAM LVVLRQGGLA PGGLNFDAKV
360 370 380 390 400
RRESSDPQDL FLAHIGGMDA FARGLEVANA LLTASPLEQW RAERYASFDS
410 420 430 440
GAGADFAAGK TTLADLAKHA ASNAPQQLSG RQEAYENLIN QYLTR
Length:445
Mass (Da):48,791
Last modified:November 22, 2005 - v1
Checksum:i4249F0C771C88ECD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM039952 Genomic DNA. Translation: CAJ26061.1.
AM039952 Genomic DNA. Translation: CAJ23485.1.
RefSeqiWP_011347136.1. NC_007508.1.

Genome annotation databases

EnsemblBacteriaiCAJ23485; CAJ23485; XCV1808.
CAJ26061; CAJ26061; XCV4330.
KEGGixcv:XCV1808.
xcv:XCV4330.
PATRICi24093160. VBIXanCam71633_2069.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM039952 Genomic DNA. Translation: CAJ26061.1.
AM039952 Genomic DNA. Translation: CAJ23485.1.
RefSeqiWP_011347136.1. NC_007508.1.

3D structure databases

ProteinModelPortaliQ3BMF2.
SMRiQ3BMF2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi316273.XCV4330.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAJ23485; CAJ23485; XCV1808.
CAJ26061; CAJ26061; XCV4330.
KEGGixcv:XCV1808.
xcv:XCV4330.
PATRICi24093160. VBIXanCam71633_2069.

Phylogenomic databases

eggNOGiENOG4105C93. Bacteria.
COG2115. LUCA.
HOGENOMiHOG000252293.
KOiK01805.
OMAiHTFQHEL.
OrthoDBiPOG091H07LC.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A. 1 hit.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiXYLA_XANC5
AccessioniPrimary (citable) accession number: Q3BMF2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: November 22, 2005
Last modified: November 2, 2016
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.