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Q3BBW0

- NBPF9_HUMAN

UniProt

Q3BBW0 - NBPF9_HUMAN

Protein

Neuroblastoma breakpoint family member 9

Gene

NBPF9

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 60 (01 Oct 2014)
      Sequence version 1 (22 Nov 2005)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Neuroblastoma breakpoint family member 9
    Gene namesi
    Name:NBPF9
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Unplaced

    Organism-specific databases

    HGNCiHGNC:31991. NBPF9.

    Subcellular locationi

    Cytoplasm Curated

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 867867Neuroblastoma breakpoint family member 9PRO_0000288044Add
    BLAST

    Proteomic databases

    PaxDbiQ3BBW0.
    PRIDEiQ3BBW0.

    Expressioni

    Tissue specificityi

    Expressed in a neuroblastoma cell line.1 Publication

    Gene expression databases

    GenevestigatoriQ3BBW0.

    Interactioni

    Protein-protein interaction databases

    STRINGi9606.ENSP00000319422.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini165 – 25995NBPF 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini436 – 52893NBPF 2PROSITE-ProRule annotationAdd
    BLAST
    Domaini529 – 61789NBPF 3PROSITE-ProRule annotationAdd
    BLAST
    Domaini620 – 67556NBPF 4PROSITE-ProRule annotationAdd
    BLAST
    Domaini676 – 76893NBPF 5PROSITE-ProRule annotationAdd
    BLAST
    Domaini769 – 86799NBPF 6PROSITE-ProRule annotationAdd
    BLAST

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili68 – 12861Sequence AnalysisAdd
    BLAST
    Coiled coili339 – 39961Sequence AnalysisAdd
    BLAST

    Sequence similaritiesi

    Belongs to the NBPF family.Curated
    Contains 6 NBPF domains.PROSITE-ProRule annotation

    Keywords - Domaini

    Coiled coil, Repeat

    Phylogenomic databases

    eggNOGibiNOG22098.
    HOGENOMiHOG000049041.
    HOVERGENiHBG058300.

    Family and domain databases

    InterProiIPR010630. NBPF_dom.
    [Graphical view]
    PfamiPF06758. DUF1220. 6 hits.
    [Graphical view]
    PROSITEiPS51316. NBPF. 6 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q3BBW0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVVSAGPLSS EKAEMNILEI NEKLHPQLAE KKQQFRNLKE KCFVTQLACF    50
    LANQQNKYKY EECKDLIKSM LRNERQFKEE KLAEQLKQAE ELRQYKVLVH 100
    SQERELTQLR EKLREGRDAS RSLNQHLQAL LTPDKPDKSQ GQDLQEQLAE 150
    GCRLAQQLFQ KLSPENDEDE DEDVQVEEAE KVLESSAPRE VQKAEESKVP 200
    EDSLEECAIT CSNSHGPCDS NQPHKNINIT FEEDKVNSAL VVDRESSHDE 250
    CQDAVNILPV PGPTSSATNV SMVVSAGPLS SEKAEMNILE INEKLHPQLA 300
    EKKQQFRNLK EKCFVTQLAC FLANQQNKYK YEECKDLIKS MLRNERQFKE 350
    EKLAEQLKQA EELRQYKVLV HSQERELTQL REKLREGRDA SRSLNQHLQA 400
    LLTPDKPDKS QGQDLQEQLA EGCRLTQHLV QKLSPENDND DDEDVQVEVA 450
    EKVQKSSAPR EMQKAEEKEV PEDSLEECAI TCSNSHGPYD SNQPHRKTKI 500
    TFEEDKVDST LTGSSSHVEW EDAVHIIPEN ESDDEEEEEK GPVSPRNLQE 550
    SEEEEVPQES WDEGYSTLSI PPEMLASYQS YSSTFHSLEE QQVCMAVDIG 600
    RHRWDQVKKE DQEATGPRLS RELLDEKGPE VLQDSLDRCY STPSGYLELP 650
    DLGQPYSSAV YSLEEQYLGL ALDVDRIKKD QEEEEDQGPP CPRLSRELLE 700
    VVEPEVLQDS LDRCYSTPSS CLEQPDSCQP YGSSFYALEE KHVGFSLDVG 750
    EIEKKGKGKK RRGRRSKKER RRGRKEGEED QNPPCPRLNG VLMEVEEPEV 800
    LQDSLDGCYS TPSMYFELPD SFQHYRSVFY SFEEQHISFA LYVDNRFFTL 850
    TVTSLHLVFQ MEVIFPQ 867
    Length:867
    Mass (Da):99,594
    Last modified:November 22, 2005 - v1
    Checksum:i8F1596E9893337E0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY894565 mRNA. Translation: AAX85104.1.
    UniGeneiHs.714127.
    Hs.721588.

    Polymorphism databases

    DMDMi121942449.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY894565 mRNA. Translation: AAX85104.1 .
    UniGenei Hs.714127.
    Hs.721588.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9606.ENSP00000319422.

    Polymorphism databases

    DMDMi 121942449.

    Proteomic databases

    PaxDbi Q3BBW0.
    PRIDEi Q3BBW0.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    GeneCardsi GC01P144614.
    HGNCi HGNC:31991. NBPF9.
    MIMi 613999. gene.
    neXtProti NX_Q3BBW0.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi biNOG22098.
    HOGENOMi HOG000049041.
    HOVERGENi HBG058300.

    Miscellaneous databases

    ChiTaRSi NBPF9. human.
    PROi Q3BBW0.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q3BBW0.

    Family and domain databases

    InterProi IPR010630. NBPF_dom.
    [Graphical view ]
    Pfami PF06758. DUF1220. 6 hits.
    [Graphical view ]
    PROSITEi PS51316. NBPF. 6 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution."
      Vandepoele K., Van Roy N., Staes K., Speleman F., van Roy F.
      Mol. Biol. Evol. 22:2265-2274(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY.
      Tissue: Mammary gland.

    Entry informationi

    Entry nameiNBPF9_HUMAN
    AccessioniPrimary (citable) accession number: Q3BBW0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 29, 2007
    Last sequence update: November 22, 2005
    Last modified: October 1, 2014
    This is version 60 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Miscellaneous

    Encoded by one of the numerous copies of NBPF genes clustered in the p36, p12 and q21 region of the chromosome 1.

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 1
      Human chromosome 1: entries, gene names and cross-references to MIM
    2. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3