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Q3BBW0

- NBPF9_HUMAN

UniProt

Q3BBW0 - NBPF9_HUMAN

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Protein
Neuroblastoma breakpoint family member 9
Gene
NBPF9
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Neuroblastoma breakpoint family member 9
Gene namesi
Name:NBPF9
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Unplaced

Organism-specific databases

HGNCiHGNC:31991. NBPF9.

Subcellular locationi

Cytoplasm Inferred

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 867867Neuroblastoma breakpoint family member 9
PRO_0000288044Add
BLAST

Proteomic databases

PaxDbiQ3BBW0.
PRIDEiQ3BBW0.

Expressioni

Tissue specificityi

Expressed in a neuroblastoma cell line.1 Publication

Gene expression databases

GenevestigatoriQ3BBW0.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000319422.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini165 – 25995NBPF 1
Add
BLAST
Domaini436 – 52893NBPF 2
Add
BLAST
Domaini529 – 61789NBPF 3
Add
BLAST
Domaini620 – 67556NBPF 4
Add
BLAST
Domaini676 – 76893NBPF 5
Add
BLAST
Domaini769 – 86799NBPF 6
Add
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili68 – 12861 Reviewed prediction
Add
BLAST
Coiled coili339 – 39961 Reviewed prediction
Add
BLAST

Sequence similaritiesi

Belongs to the NBPF family.
Contains 6 NBPF domains.

Keywords - Domaini

Coiled coil, Repeat

Phylogenomic databases

eggNOGibiNOG22098.
HOGENOMiHOG000049041.
HOVERGENiHBG058300.

Family and domain databases

InterProiIPR010630. NBPF_dom.
[Graphical view]
PfamiPF06758. DUF1220. 6 hits.
[Graphical view]
PROSITEiPS51316. NBPF. 6 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3BBW0-1 [UniParc]FASTAAdd to Basket

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MVVSAGPLSS EKAEMNILEI NEKLHPQLAE KKQQFRNLKE KCFVTQLACF    50
LANQQNKYKY EECKDLIKSM LRNERQFKEE KLAEQLKQAE ELRQYKVLVH 100
SQERELTQLR EKLREGRDAS RSLNQHLQAL LTPDKPDKSQ GQDLQEQLAE 150
GCRLAQQLFQ KLSPENDEDE DEDVQVEEAE KVLESSAPRE VQKAEESKVP 200
EDSLEECAIT CSNSHGPCDS NQPHKNINIT FEEDKVNSAL VVDRESSHDE 250
CQDAVNILPV PGPTSSATNV SMVVSAGPLS SEKAEMNILE INEKLHPQLA 300
EKKQQFRNLK EKCFVTQLAC FLANQQNKYK YEECKDLIKS MLRNERQFKE 350
EKLAEQLKQA EELRQYKVLV HSQERELTQL REKLREGRDA SRSLNQHLQA 400
LLTPDKPDKS QGQDLQEQLA EGCRLTQHLV QKLSPENDND DDEDVQVEVA 450
EKVQKSSAPR EMQKAEEKEV PEDSLEECAI TCSNSHGPYD SNQPHRKTKI 500
TFEEDKVDST LTGSSSHVEW EDAVHIIPEN ESDDEEEEEK GPVSPRNLQE 550
SEEEEVPQES WDEGYSTLSI PPEMLASYQS YSSTFHSLEE QQVCMAVDIG 600
RHRWDQVKKE DQEATGPRLS RELLDEKGPE VLQDSLDRCY STPSGYLELP 650
DLGQPYSSAV YSLEEQYLGL ALDVDRIKKD QEEEEDQGPP CPRLSRELLE 700
VVEPEVLQDS LDRCYSTPSS CLEQPDSCQP YGSSFYALEE KHVGFSLDVG 750
EIEKKGKGKK RRGRRSKKER RRGRKEGEED QNPPCPRLNG VLMEVEEPEV 800
LQDSLDGCYS TPSMYFELPD SFQHYRSVFY SFEEQHISFA LYVDNRFFTL 850
TVTSLHLVFQ MEVIFPQ 867
Length:867
Mass (Da):99,594
Last modified:November 22, 2005 - v1
Checksum:i8F1596E9893337E0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY894565 mRNA. Translation: AAX85104.1.
UniGeneiHs.714127.
Hs.721588.

Polymorphism databases

DMDMi121942449.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY894565 mRNA. Translation: AAX85104.1 .
UniGenei Hs.714127.
Hs.721588.

3D structure databases

ModBasei Search...

Protein-protein interaction databases

STRINGi 9606.ENSP00000319422.

Polymorphism databases

DMDMi 121942449.

Proteomic databases

PaxDbi Q3BBW0.
PRIDEi Q3BBW0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

GeneCardsi GC01P144614.
HGNCi HGNC:31991. NBPF9.
MIMi 613999. gene.
neXtProti NX_Q3BBW0.
GenAtlasi Search...

Phylogenomic databases

eggNOGi biNOG22098.
HOGENOMi HOG000049041.
HOVERGENi HBG058300.

Miscellaneous databases

ChiTaRSi NBPF9. human.
PROi Q3BBW0.
SOURCEi Search...

Gene expression databases

Genevestigatori Q3BBW0.

Family and domain databases

InterProi IPR010630. NBPF_dom.
[Graphical view ]
Pfami PF06758. DUF1220. 6 hits.
[Graphical view ]
PROSITEi PS51316. NBPF. 6 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution."
    Vandepoele K., Van Roy N., Staes K., Speleman F., van Roy F.
    Mol. Biol. Evol. 22:2265-2274(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY.
    Tissue: Mammary gland.

Entry informationi

Entry nameiNBPF9_HUMAN
AccessioniPrimary (citable) accession number: Q3BBW0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: November 22, 2005
Last modified: January 22, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Miscellaneous

Encoded by one of the numerous copies of NBPF genes clustered in the p36, p12 and q21 region of the chromosome 1.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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