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Q3BBW0 (NBPF9_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified January 22, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Neuroblastoma breakpoint family member 9
Gene names
Name:NBPF9
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length867 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Cytoplasm Probable.

Tissue specificity

Expressed in a neuroblastoma cell line. Ref.1

Miscellaneous

Encoded by one of the numerous copies of NBPF genes clustered in the p36, p12 and q21 region of the chromosome 1.

Sequence similarities

Belongs to the NBPF family.

Contains 6 NBPF domains.

Ontologies

Keywords
   Cellular componentCytoplasm
   DomainCoiled coil
Repeat
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 867867Neuroblastoma breakpoint family member 9
PRO_0000288044

Regions

Domain165 – 25995NBPF 1
Domain436 – 52893NBPF 2
Domain529 – 61789NBPF 3
Domain620 – 67556NBPF 4
Domain676 – 76893NBPF 5
Domain769 – 86799NBPF 6
Coiled coil68 – 12861 Potential
Coiled coil339 – 39961 Potential

Sequences

Sequence LengthMass (Da)Tools
Q3BBW0 [UniParc].

Last modified November 22, 2005. Version 1.
Checksum: 8F1596E9893337E0

FASTA86799,594
        10         20         30         40         50         60 
MVVSAGPLSS EKAEMNILEI NEKLHPQLAE KKQQFRNLKE KCFVTQLACF LANQQNKYKY 

        70         80         90        100        110        120 
EECKDLIKSM LRNERQFKEE KLAEQLKQAE ELRQYKVLVH SQERELTQLR EKLREGRDAS 

       130        140        150        160        170        180 
RSLNQHLQAL LTPDKPDKSQ GQDLQEQLAE GCRLAQQLFQ KLSPENDEDE DEDVQVEEAE 

       190        200        210        220        230        240 
KVLESSAPRE VQKAEESKVP EDSLEECAIT CSNSHGPCDS NQPHKNINIT FEEDKVNSAL 

       250        260        270        280        290        300 
VVDRESSHDE CQDAVNILPV PGPTSSATNV SMVVSAGPLS SEKAEMNILE INEKLHPQLA 

       310        320        330        340        350        360 
EKKQQFRNLK EKCFVTQLAC FLANQQNKYK YEECKDLIKS MLRNERQFKE EKLAEQLKQA 

       370        380        390        400        410        420 
EELRQYKVLV HSQERELTQL REKLREGRDA SRSLNQHLQA LLTPDKPDKS QGQDLQEQLA 

       430        440        450        460        470        480 
EGCRLTQHLV QKLSPENDND DDEDVQVEVA EKVQKSSAPR EMQKAEEKEV PEDSLEECAI 

       490        500        510        520        530        540 
TCSNSHGPYD SNQPHRKTKI TFEEDKVDST LTGSSSHVEW EDAVHIIPEN ESDDEEEEEK 

       550        560        570        580        590        600 
GPVSPRNLQE SEEEEVPQES WDEGYSTLSI PPEMLASYQS YSSTFHSLEE QQVCMAVDIG 

       610        620        630        640        650        660 
RHRWDQVKKE DQEATGPRLS RELLDEKGPE VLQDSLDRCY STPSGYLELP DLGQPYSSAV 

       670        680        690        700        710        720 
YSLEEQYLGL ALDVDRIKKD QEEEEDQGPP CPRLSRELLE VVEPEVLQDS LDRCYSTPSS 

       730        740        750        760        770        780 
CLEQPDSCQP YGSSFYALEE KHVGFSLDVG EIEKKGKGKK RRGRRSKKER RRGRKEGEED 

       790        800        810        820        830        840 
QNPPCPRLNG VLMEVEEPEV LQDSLDGCYS TPSMYFELPD SFQHYRSVFY SFEEQHISFA 

       850        860 
LYVDNRFFTL TVTSLHLVFQ MEVIFPQ 

« Hide

References

[1]"A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution."
Vandepoele K., Van Roy N., Staes K., Speleman F., van Roy F.
Mol. Biol. Evol. 22:2265-2274(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY.
Tissue: Mammary gland.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY894565 mRNA. Translation: AAX85104.1.
UniGeneHs.714127.
Hs.721588.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING9606.ENSP00000319422.

Polymorphism databases

DMDM121942449.

Proteomic databases

PaxDbQ3BBW0.
PRIDEQ3BBW0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

GeneCardsGC01P144614.
HGNCHGNC:31991. NBPF9.
MIM613999. gene.
neXtProtNX_Q3BBW0.
GenAtlasSearch...

Phylogenomic databases

eggNOGbiNOG22098.
HOGENOMHOG000049041.
HOVERGENHBG058300.

Gene expression databases

GenevestigatorQ3BBW0.

Family and domain databases

InterProIPR010630. NBPF_dom.
[Graphical view]
PfamPF06758. DUF1220. 6 hits.
[Graphical view]
PROSITEPS51316. NBPF. 6 hits.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSNBPF9. human.
PROQ3BBW0.
SOURCESearch...

Entry information

Entry nameNBPF9_HUMAN
AccessionPrimary (citable) accession number: Q3BBW0
Entry history
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: November 22, 2005
Last modified: January 22, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Human chromosome 1

Human chromosome 1: entries, gene names and cross-references to MIM