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Q3B826

- Q3B826_HUMAN

UniProt

Q3B826 - Q3B826_HUMAN

Protein

Metalloendopeptidase

Gene

ASTL

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 47 (01 Oct 2014)
      Sequence version 1 (22 Nov 2005)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 zinc ion per subunit.UniRule annotation

    GO - Molecular functioni

    1. metalloendopeptidase activity Source: InterPro
    2. zinc ion binding Source: InterPro

    Keywords - Molecular functioni

    Hydrolase, MetalloproteaseUniRule annotation, Protease

    Keywords - Ligandi

    Metal-bindingUniRule annotationSAAS annotation, ZincUniRule annotationSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    MetalloendopeptidaseUniRule annotation (EC:3.4.24.-UniRule annotation)
    Gene namesi
    Name:ASTLImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    PTM / Processingi

    Proteomic databases

    PRIDEiQ3B826.

    Structurei

    3D structure databases

    ProteinModelPortaliQ3B826.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the peptidase M12A family.UniRule annotation

    Keywords - Domaini

    SignalUniRule annotation

    Phylogenomic databases

    HOVERGENiHBG080299.

    Family and domain databases

    Gene3Di3.40.390.10. 1 hit.
    InterProiIPR024079. MetalloPept_cat_dom.
    IPR001506. Peptidase_M12A.
    IPR006026. Peptidase_Metallo.
    [Graphical view]
    PfamiPF01400. Astacin. 1 hit.
    [Graphical view]
    PRINTSiPR00480. ASTACIN.
    SMARTiSM00235. ZnMc. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q3B826-1 [UniParc]FASTAAdd to Basket

    « Hide

    EGVGGLWPWV LGLLSLPGVI LGAPLASSCA GACGTSFPDG LTPEGTQASG    50
    DKDIPAINQG LILEETPESS FLIEGDIIRP SPFRLLSATS NKWPMGGSGV 100
    VEVPFLLSSK YDEPSRQVIL EALAEFERST CIRFVTYQDQ RDFISIIPMY 150
    GCFSSVGRSG GMQVVSLAPT CLQKGRGIVL HELMHVLGFW HEHTRADRDR 200
    YIRVNWNEIL PGFEINFIKS RSSNMLTPYD YSSVMHYGRL AFSRRGLPTI 250
    TPLWAPSVHI GQRWNLSASD ITRVLQLYGC SPSGPRPRGR GSHAHSTGRS 300
    PAPASLSLQR LLEALSAESR SPDPSGSSAG GQPVPAGPGE SPHGWESPAL 350
    KKLSAEASAR QPQTLASSPR SRPGAGAPGV AQEQSWLAGV STKPTVPSSE 400
    AGIQPVPVQG SPALPGGCVP RNHFKGMSED 430
    Length:430
    Mass (Da):45,833
    Last modified:November 22, 2005 - v1
    Checksum:i619ED8B901CA279D
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC107126 mRNA. Translation: AAI07127.1.
    UniGeneiHs.447993.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC107126 mRNA. Translation: AAI07127.1 .
    UniGenei Hs.447993.

    3D structure databases

    ProteinModelPortali Q3B826.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q3B826.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG080299.

    Family and domain databases

    Gene3Di 3.40.390.10. 1 hit.
    InterProi IPR024079. MetalloPept_cat_dom.
    IPR001506. Peptidase_M12A.
    IPR006026. Peptidase_Metallo.
    [Graphical view ]
    Pfami PF01400. Astacin. 1 hit.
    [Graphical view ]
    PRINTSi PR00480. ASTACIN.
    SMARTi SM00235. ZnMc. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

    Entry informationi

    Entry nameiQ3B826_HUMAN
    AccessioniPrimary (citable) accession number: Q3B826
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 22, 2005
    Last sequence update: November 22, 2005
    Last modified: October 1, 2014
    This is version 47 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.