Q3B826 (Q3B826_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
ASTL protein EMBL AAI07127.1

Gene names

Name:

ASTL EMBL AAI07127.1

Organism

Homo sapiens (Human) EMBL AAI07127.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	430 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the peptidase M12A family. RuleBase RU004522

Ontologies

Keywords
Ligand	Metal-binding SAAS SAAS001506 Zinc SAAS SAAS001506
Molecular function	Hydrolase Metalloprotease SAAS SAAS001506 Protease
Gene Ontology (GO)
Biological_process	proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAI07127.1

Sequences

	Sequence		Length	Mass (Da)
	Q3B826 [UniParc]. Last modified November 22, 2005. Version 1. Checksum: 619ED8B901CA279D	FASTA	430	45,833
	10 20 30 40 50 60 EGVGGLWPWV LGLLSLPGVI LGAPLASSCA GACGTSFPDG LTPEGTQASG DKDIPAINQG 70 80 90 100 110 120 LILEETPESS FLIEGDIIRP SPFRLLSATS NKWPMGGSGV VEVPFLLSSK YDEPSRQVIL 130 140 150 160 170 180 EALAEFERST CIRFVTYQDQ RDFISIIPMY GCFSSVGRSG GMQVVSLAPT CLQKGRGIVL 190 200 210 220 230 240 HELMHVLGFW HEHTRADRDR YIRVNWNEIL PGFEINFIKS RSSNMLTPYD YSSVMHYGRL 250 260 270 280 290 300 AFSRRGLPTI TPLWAPSVHI GQRWNLSASD ITRVLQLYGC SPSGPRPRGR GSHAHSTGRS 310 320 330 340 350 360 PAPASLSLQR LLEALSAESR SPDPSGSSAG GQPVPAGPGE SPHGWESPAL KKLSAEASAR 370 380 390 400 410 420 QPQTLASSPR SRPGAGAPGV AQEQSWLAGV STKPTVPSSE AGIQPVPVQG SPALPGGCVP 430 RNHFKGMSED

References

[1]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J. Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC107126 mRNA. Translation: AAI07127.1.
IPI	IPI00436526.
UniGene	Hs.447993.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG080299.
Family and domain databases
Gene3D	3.40.390.10. 1 hit.
InterPro	IPR024079. MetalloPept_cat_dom. IPR001506. Peptidase_M12A. IPR006026. Peptidase_Metallo. [Graphical view]
Pfam	PF01400. Astacin. 1 hit. [Graphical view]
PRINTS	PR00480. ASTACIN.
SMART	SM00235. ZnMc. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q3B826_HUMAN

Accession

Primary (citable) accession number: Q3B826

Entry history

Integrated into UniProtKB/TrEMBL:	November 22, 2005
Last sequence update:	November 22, 2005
Last modified:	May 29, 2013
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.