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Protein
Submitted name:

Dehydrogenase/reductase (SDR family) member 3

Gene

Dhrs3

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-RNO-2187335. The retinoid cycle in cones (daylight vision).
R-RNO-5365859. RA biosynthesis pathway.

Names & Taxonomyi

Protein namesi
Submitted name:
Dehydrogenase/reductase (SDR family) member 3Imported
Submitted name:
Dehydrogenase/reductase (SDR family) member 3, isoform CRA_bImported
Submitted name:
Protein Dhrs3Imported
Gene namesi
Name:Dhrs3Imported
ORF Names:rCG_31196Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 5

Organism-specific databases

RGDi1305584. Dhrs3.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei6 – 2924HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSRNOG00000015736.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000021155.

Family & Domainsi

Sequence similaritiesi

Belongs to the short-chain dehydrogenases/reductases (SDR) family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1201. Eukaryota.
COG1028. LUCA.
GeneTreeiENSGT00540000069900.
HOVERGENiHBG051352.
KOiK11146.
OMAiWTMHALI.
OrthoDBiEOG091G0825.
TreeFamiTF312837.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR032969. DHRS3.
IPR016040. NAD(P)-bd_dom.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 2 hits.
PTHR24322:SF483. PTHR24322:SF483. 2 hits.
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3B7V0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVWKWLGALV VLPLQMIYLV TKAAVGLVLP PKLRDLSRES VLITGGGRGI
60 70 80 90 100
GRHLAREFAE RGARKIVLWG RTEKCLKETT EEIRQMGTEC HYFICDVGNR
110 120 130 140 150
EEVYQMAKAV REKVGDITIL VNNAAVVHGK SLMDSDDDAL LKSQHVNTLG
160 170 180 190 200
QFWTTKAFLP RMLELQNGHI VCLNSVLALS AIPGAIDYCT SKASAFAFME
210 220 230 240 250
SLTLGLLDCP GVSATTVLPF HTSTEMFQGM RVRFPNLFPP LKPETVARRT
260 270 280 290 300
VEAVQQNQAL LLLPWTMNIL IILKSILPQA ALEEIHRFSG TYTCMNTFKG

RT
Length:302
Mass (Da):33,614
Last modified:November 22, 2005 - v1
Checksum:i3102211B519E6036
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07050379 Genomic DNA. No translation available.
BC107450 mRNA. Translation: AAI07451.1.
CH473968 Genomic DNA. Translation: EDL81061.1.
RefSeqiNP_001032276.3. NM_001037199.3.
UniGeneiRn.12011.

Genome annotation databases

EnsembliENSRNOT00000021155; ENSRNOP00000021155; ENSRNOG00000015736.
GeneIDi313689.
KEGGirno:313689.
UCSCiRGD:1305584. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07050379 Genomic DNA. No translation available.
BC107450 mRNA. Translation: AAI07451.1.
CH473968 Genomic DNA. Translation: EDL81061.1.
RefSeqiNP_001032276.3. NM_001037199.3.
UniGeneiRn.12011.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000021155.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000021155; ENSRNOP00000021155; ENSRNOG00000015736.
GeneIDi313689.
KEGGirno:313689.
UCSCiRGD:1305584. rat.

Organism-specific databases

CTDi9249.
RGDi1305584. Dhrs3.

Phylogenomic databases

eggNOGiKOG1201. Eukaryota.
COG1028. LUCA.
GeneTreeiENSGT00540000069900.
HOVERGENiHBG051352.
KOiK11146.
OMAiWTMHALI.
OrthoDBiEOG091G0825.
TreeFamiTF312837.

Enzyme and pathway databases

ReactomeiR-RNO-2187335. The retinoid cycle in cones (daylight vision).
R-RNO-5365859. RA biosynthesis pathway.

Gene expression databases

BgeeiENSRNOG00000015736.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR032969. DHRS3.
IPR016040. NAD(P)-bd_dom.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 2 hits.
PTHR24322:SF483. PTHR24322:SF483. 2 hits.
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ3B7V0_RAT
AccessioniPrimary (citable) accession number: Q3B7V0
Entry historyi
Integrated into UniProtKB/TrEMBL: November 22, 2005
Last sequence update: November 22, 2005
Last modified: September 7, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.