Q3B7T1 (EDRF1_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Erythroid differentiation-related factor 1

Gene names

Name:	EDRF1
Synonyms:	C10orf137

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	1238 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Transcription factor involved in erythroid differentiation. Involved in transcriptional activation of the globin gene. Ref.5
Subcellular location	Nucleus Probable.
Sequence similarities	Contains 2 TPR repeats.
Sequence caution	The sequence BAG37462.1 differs from that shown. Reason: Erroneous initiation. The sequence CAH73214.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Cellular component	Nucleus
Coding sequence diversity	Alternative splicing Polymorphism
Domain	Repeat TPR repeat
Molecular function	Activator
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Alternative products

This entry describes 4 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q3B7T1-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q3B7T1-3)

The sequence of this isoform differs from the canonical sequence as follows:
     793-796: AWAT → KTGK
     797-1238: Missing.

Note: No experimental confirmation available. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.

Isoform 3 (identifier: Q3B7T1-4)

The sequence of this isoform differs from the canonical sequence as follows:
     587-593: PSCAFPV → LCISSLP
     594-1238: Missing.

Note: No experimental confirmation available. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.

Isoform 4 (identifier: Q3B7T1-5)

The sequence of this isoform differs from the canonical sequence as follows:
     266-299: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1238	1238	Erythroid differentiation-related factor 1		PRO_0000244260
Regions
	Repeat	693 – 726	34	TPR 1
	Repeat	914 – 953	40	TPR 2
Natural variations
	Alternative sequence	266 – 299	34	Missing in isoform 4.		VSP_035712
	Alternative sequence	587 – 593	7	PSCAFPV → LCISSLP in isoform 3.		VSP_035713
	Alternative sequence	594 – 1238	645	Missing in isoform 3.		VSP_035714
	Alternative sequence	793 – 796	4	AWAT → KTGK in isoform 2.		VSP_019531
	Alternative sequence	797 – 1238	442	Missing in isoform 2.		VSP_019532
	Natural variant	45	1	N → S in a colorectal cancer sample; somatic mutation. Ref.7		VAR_035862
	Natural variant	95	1	L → F in a colorectal cancer sample; somatic mutation. Ref.7		VAR_035863
Experimental info
	Sequence conflict	443	1	E → G in AAH26172. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified November 22, 2005. Version 1. Checksum: 9B4D5130EB10CF95	FASTA	1,238	138,528
	10 20 30 40 50 60 MGDAKEAGAE GPPAGAAARG GLSLLSQGES EESSAQGSAL FLGGNEVKSR AVVKYSSAPP 70 80 90 100 110 120 RTAFARLEEK TDLKLPPANW LRESAKLGPA GTTILGNSKK SKPFSSFGMA YDFIDSVGND 130 140 150 160 170 180 VDVVSDSENI KKLLKIPYSK SHVSMAVHRI GRTLLLDELD IQELFMRSSQ TGDWTWLKEF 190 200 210 220 230 240 YQRLIDQKWQ RKKKSKEHWY QKAILSKFLY YSINGDGAAQ PVSSTAEQQE SSSSDQTNDS 250 260 270 280 290 300 EGASWPAPFE MPSSVSEDPS ASSQGSEPLE PSYIVGHVAS APKEQNLITL FNDGEHSQGL 310 320 330 340 350 360 KNDFVRNILW TFEDIHMLVG SNMPIFGGGR YPAVSLRLRD NNKPINVLTG IDYWLDNLIC 370 380 390 400 410 420 NVPELVMCFH VNGIVQKYEM IKTEEIPNLE NSNFSTKVIK DIAQNILSFL KSNCTKEGHT 430 440 450 460 470 480 YWLFKASGSD IVKLYDLTTL CEETEDKYQN PFTMPVAILL YKVACNMMMK KNQNKKHYGT 490 500 510 520 530 540 IRTLLLNCLK LLDKSRHPQI IASANYMLSE LFQLDEPKKE ENSESPLNEN SDESYSEEEE 550 560 570 580 590 600 EMPDSDENGS YSTSSDPSDD SKAVAIIKSV GELSVPEKYK SIHQIRPSCA FPVCHDTEER 610 620 630 640 650 660 CRLVLSYVLE GLKSVDSSIK KESDLPAADP STPIPLKYED ESSRGGPEGL EKQMALFLDK 670 680 690 700 710 720 MGSLQKGNYS SQSGMIPGSW QHKMKLQLIL KSSKAYYVLS DAAMSLQKYG RALRYIKLAL 730 740 750 760 770 780 QSHDTYCCLC TNMLSEVLLF LSQYLTLCGD IQLMLAQNAN NRAAHLEEFH YQTKEDQEIL 790 800 810 820 830 840 HSLHRESSCQ GFAWATDLST DLESQLSVSC KCYEAANEIL QFSDLKSQNP EHYVQVLKRM 850 860 870 880 890 900 GNIRNEIGVF YMNQAAALQS ERLVSKSVSA AEQQLWKKSF SCFEKGIHNF ESIEDATNAA 910 920 930 940 950 960 LLLCNTGRLM RICAQAHCGA GDELKREFSP EEGLYYNKAI DYYLKALRSL GTRDIHPAVW 970 980 990 1000 1010 1020 DSVNWELSTT YFTMATLQQD YAPLSRKAQE QIEKEVSEAM MKSLKYCDVD SVSARQPLCQ 1030 1040 1050 1060 1070 1080 YRAATIHHRL ASMYHSCLRN QVGDEHLRKQ HRVLADLHYS KAAKLFQLLK DAPCELLRVQ 1090 1100 1110 1120 1130 1140 LERVAFAEFQ MTSQNSNVGK LKTLSGALDI MVRTEHAFQL IQKELIEEFG QPKSGDAAAA 1150 1160 1170 1180 1190 1200 ADASPSLNRE EVMKLLSIFE SRLSFLLLQS IKLLSSTKKK TSNNIEDDTI LKTNKHIYSQ 1210 1220 1230 LLRATANKTA TLLERINVIV HLLGQLAAGS AASSNAVQ
	Isoform 2 [UniParc]. Checksum: C3BA9B8B1A71B8CD	FASTA	796	88,851
	10 20 30 40 50 60 MGDAKEAGAE GPPAGAAARG GLSLLSQGES EESSAQGSAL FLGGNEVKSR AVVKYSSAPP 70 80 90 100 110 120 RTAFARLEEK TDLKLPPANW LRESAKLGPA GTTILGNSKK SKPFSSFGMA YDFIDSVGND 130 140 150 160 170 180 VDVVSDSENI KKLLKIPYSK SHVSMAVHRI GRTLLLDELD IQELFMRSSQ TGDWTWLKEF 190 200 210 220 230 240 YQRLIDQKWQ RKKKSKEHWY QKAILSKFLY YSINGDGAAQ PVSSTAEQQE SSSSDQTNDS 250 260 270 280 290 300 EGASWPAPFE MPSSVSEDPS ASSQGSEPLE PSYIVGHVAS APKEQNLITL FNDGEHSQGL 310 320 330 340 350 360 KNDFVRNILW TFEDIHMLVG SNMPIFGGGR YPAVSLRLRD NNKPINVLTG IDYWLDNLIC 370 380 390 400 410 420 NVPELVMCFH VNGIVQKYEM IKTEEIPNLE NSNFSTKVIK DIAQNILSFL KSNCTKEGHT 430 440 450 460 470 480 YWLFKASGSD IVKLYDLTTL CEETEDKYQN PFTMPVAILL YKVACNMMMK KNQNKKHYGT 490 500 510 520 530 540 IRTLLLNCLK LLDKSRHPQI IASANYMLSE LFQLDEPKKE ENSESPLNEN SDESYSEEEE 550 560 570 580 590 600 EMPDSDENGS YSTSSDPSDD SKAVAIIKSV GELSVPEKYK SIHQIRPSCA FPVCHDTEER 610 620 630 640 650 660 CRLVLSYVLE GLKSVDSSIK KESDLPAADP STPIPLKYED ESSRGGPEGL EKQMALFLDK 670 680 690 700 710 720 MGSLQKGNYS SQSGMIPGSW QHKMKLQLIL KSSKAYYVLS DAAMSLQKYG RALRYIKLAL 730 740 750 760 770 780 QSHDTYCCLC TNMLSEVLLF LSQYLTLCGD IQLMLAQNAN NRAAHLEEFH YQTKEDQEIL 790 HSLHRESSCQ GFKTGK
	Isoform 3 [UniParc]. Checksum: BF58C4A954507048	FASTA	593	66,004
	10 20 30 40 50 60 MGDAKEAGAE GPPAGAAARG GLSLLSQGES EESSAQGSAL FLGGNEVKSR AVVKYSSAPP 70 80 90 100 110 120 RTAFARLEEK TDLKLPPANW LRESAKLGPA GTTILGNSKK SKPFSSFGMA YDFIDSVGND 130 140 150 160 170 180 VDVVSDSENI KKLLKIPYSK SHVSMAVHRI GRTLLLDELD IQELFMRSSQ TGDWTWLKEF 190 200 210 220 230 240 YQRLIDQKWQ RKKKSKEHWY QKAILSKFLY YSINGDGAAQ PVSSTAEQQE SSSSDQTNDS 250 260 270 280 290 300 EGASWPAPFE MPSSVSEDPS ASSQGSEPLE PSYIVGHVAS APKEQNLITL FNDGEHSQGL 310 320 330 340 350 360 KNDFVRNILW TFEDIHMLVG SNMPIFGGGR YPAVSLRLRD NNKPINVLTG IDYWLDNLIC 370 380 390 400 410 420 NVPELVMCFH VNGIVQKYEM IKTEEIPNLE NSNFSTKVIK DIAQNILSFL KSNCTKEGHT 430 440 450 460 470 480 YWLFKASGSD IVKLYDLTTL CEETEDKYQN PFTMPVAILL YKVACNMMMK KNQNKKHYGT 490 500 510 520 530 540 IRTLLLNCLK LLDKSRHPQI IASANYMLSE LFQLDEPKKE ENSESPLNEN SDESYSEEEE 550 560 570 580 590 EMPDSDENGS YSTSSDPSDD SKAVAIIKSV GELSVPEKYK SIHQIRLCIS SLP
	Isoform 4 [UniParc]. Checksum: 02189CCD55CF0AF7	FASTA	1,204	134,881
	10 20 30 40 50 60 MGDAKEAGAE GPPAGAAARG GLSLLSQGES EESSAQGSAL FLGGNEVKSR AVVKYSSAPP 70 80 90 100 110 120 RTAFARLEEK TDLKLPPANW LRESAKLGPA GTTILGNSKK SKPFSSFGMA YDFIDSVGND 130 140 150 160 170 180 VDVVSDSENI KKLLKIPYSK SHVSMAVHRI GRTLLLDELD IQELFMRSSQ TGDWTWLKEF 190 200 210 220 230 240 YQRLIDQKWQ RKKKSKEHWY QKAILSKFLY YSINGDGAAQ PVSSTAEQQE SSSSDQTNDS 250 260 270 280 290 300 EGASWPAPFE MPSSVSEDPS ASSQGLKNDF VRNILWTFED IHMLVGSNMP IFGGGRYPAV 310 320 330 340 350 360 SLRLRDNNKP INVLTGIDYW LDNLICNVPE LVMCFHVNGI VQKYEMIKTE EIPNLENSNF 370 380 390 400 410 420 STKVIKDIAQ NILSFLKSNC TKEGHTYWLF KASGSDIVKL YDLTTLCEET EDKYQNPFTM 430 440 450 460 470 480 PVAILLYKVA CNMMMKKNQN KKHYGTIRTL LLNCLKLLDK SRHPQIIASA NYMLSELFQL 490 500 510 520 530 540 DEPKKEENSE SPLNENSDES YSEEEEEMPD SDENGSYSTS SDPSDDSKAV AIIKSVGELS 550 560 570 580 590 600 VPEKYKSIHQ IRPSCAFPVC HDTEERCRLV LSYVLEGLKS VDSSIKKESD LPAADPSTPI 610 620 630 640 650 660 PLKYEDESSR GGPEGLEKQM ALFLDKMGSL QKGNYSSQSG MIPGSWQHKM KLQLILKSSK 670 680 690 700 710 720 AYYVLSDAAM SLQKYGRALR YIKLALQSHD TYCCLCTNML SEVLLFLSQY LTLCGDIQLM 730 740 750 760 770 780 LAQNANNRAA HLEEFHYQTK EDQEILHSLH RESSCQGFAW ATDLSTDLES QLSVSCKCYE 790 800 810 820 830 840 AANEILQFSD LKSQNPEHYV QVLKRMGNIR NEIGVFYMNQ AAALQSERLV SKSVSAAEQQ 850 860 870 880 890 900 LWKKSFSCFE KGIHNFESIE DATNAALLLC NTGRLMRICA QAHCGAGDEL KREFSPEEGL 910 920 930 940 950 960 YYNKAIDYYL KALRSLGTRD IHPAVWDSVN WELSTTYFTM ATLQQDYAPL SRKAQEQIEK 970 980 990 1000 1010 1020 EVSEAMMKSL KYCDVDSVSA RQPLCQYRAA TIHHRLASMY HSCLRNQVGD EHLRKQHRVL 1030 1040 1050 1060 1070 1080 ADLHYSKAAK LFQLLKDAPC ELLRVQLERV AFAEFQMTSQ NSNVGKLKTL SGALDIMVRT 1090 1100 1110 1120 1130 1140 EHAFQLIQKE LIEEFGQPKS GDAAAAADAS PSLNREEVMK LLSIFESRLS FLLLQSIKLL 1150 1160 1170 1180 1190 1200 SSTKKKTSNN IEDDTILKTN KHIYSQLLRA TANKTATLLE RINVIVHLLG QLAAGSAASS NAVQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The DNA sequence and comparative analysis of human chromosome 10." Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J. , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J. Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2 AND 3). Tissue: Testis.
[3]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 659-1238 (ISOFORMS 1/4). Tissue: Lymphoblast.
[4]	"The full-ORF clone resource of the German cDNA consortium." Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I. BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 745-1238 (ISOFORMS 1/4). Tissue: Uterus.
[5]	"A novel erythroid differentiation related gene EDRF1 upregulating globin gene expression in HEL cells." Wang D., Li Y., Shen B. Chin. Med. J. 115:1701-1705(2002) [PubMed] [Europe PMC] [Abstract] Cited for: FUNCTION.
[6]	"Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[7]	"The consensus coding sequences of human breast and colorectal cancers." Sjoeblom T., Jones S., Wood L.D., Parsons D.W., Lin J., Barber T.D., Mandelker D., Leary R.J., Ptak J., Silliman N., Szabo S., Buckhaults P., Farrell C., Meeh P., Markowitz S.D., Willis J., Dawson D., Willson J.K.V. , Gazdar A.F., Hartigan J., Wu L., Liu C., Parmigiani G., Park B.H., Bachman K.E., Papadopoulos N., Vogelstein B., Kinzler K.W., Velculescu V.E. Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract] Cited for: VARIANTS [LARGE SCALE ANALYSIS] SER-45 AND PHE-95.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL158835 Genomic DNA. Translation: CAH73214.1. Sequence problems. BC026172 mRNA. Translation: AAH26172.1. BC105929 mRNA. Translation: AAI05930.1. BC107479 mRNA. Translation: AAI07480.1. AK314958 mRNA. Translation: BAG37462.1. Different initiation. AL050102 mRNA. Translation: CAB43273.1.
IPI	IPI00746361. IPI00761051. IPI00844267. IPI00914869.
PIR	T08751.
RefSeq	NP_001189367.1. NM_001202438.1. NP_056423.2. NM_015608.2.
UniGene	Hs.468688.
3D structure databases
ProteinModelPortal	Q3B7T1.
SMR	Q3B7T1. Positions 695-722.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q3B7T1. 2 interactions.
STRING	9606.ENSP00000336727.
PTM databases
PhosphoSite	Q3B7T1.
Polymorphism databases
DMDM	109826957.
Proteomic databases
PaxDb	Q3B7T1.
PRIDE	Q3B7T1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000337623; ENSP00000336727; ENSG00000107938. ENST00000356792; ENSP00000349244; ENSG00000107938. ENST00000368815; ENSP00000357805; ENSG00000107938. ENST00000419769; ENSP00000396544; ENSG00000107938.
GeneID	26098.
KEGG	hsa:26098.
UCSC	uc001lin.3. human. uc001lip.1. human.
Organism-specific databases
CTD	26098.
GeneCards	GC10P127408.
HGNC	HGNC:24640. C10orf137.
HPA	HPA031820.
neXtProt	NX_Q3B7T1.
PharmGKB	PA134873666.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG79617.
HOVERGEN	HBG081471.
OMA	EMIKTED.
Gene expression databases
ArrayExpress	Q3B7T1.
Bgee	Q3B7T1.
CleanEx	HS_C10orf137.
Genevestigator	Q3B7T1.
Family and domain databases
PROSITE	PS50005. TPR. False negative. PS50293. TPR_REGION. False negative. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	C10orf137. human.
GenomeRNAi	26098.
NextBio	48077.
PMAP-CutDB	Q3B7T1.

Entry information

Entry name

EDRF1_HUMAN

Accession

Primary (citable) accession number: Q3B7T1
Secondary accession number(s): B2RC65 , Q3KR40, Q4G190, Q5VZQ4, Q8IZ74, Q9Y3W4

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
Last sequence update:	November 22, 2005
Last modified:	May 1, 2013
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.