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Q3B7S5

- SMI21_HUMAN

UniProt

Q3B7S5 - SMI21_HUMAN

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Protein

Small integral membrane protein 21

Gene

SMIM21

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Small integral membrane protein 21
Gene namesi
Name:SMIM21
Synonyms:C18orf62
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 18

Organism-specific databases

HGNCiHGNC:27598. SMIM21.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei49 – 6517HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162378613.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 101101Small integral membrane protein 21PRO_0000340722Add
BLAST

Proteomic databases

PaxDbiQ3B7S5.
PRIDEiQ3B7S5.

Expressioni

Gene expression databases

BgeeiQ3B7S5.
CleanExiHS_C18orf62.
ExpressionAtlasiQ3B7S5. baseline and differential.
GenevestigatoriQ3B7S5.

Organism-specific databases

HPAiCAB034243.
HPA041686.

Structurei

3D structure databases

ProteinModelPortaliQ3B7S5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG135016.
GeneTreeiENSGT00410000028836.
HOGENOMiHOG000111963.
InParanoidiQ3B7S5.
OMAiENEHHIR.
OrthoDBiEOG7N63Q1.
PhylomeDBiQ3B7S5.

Sequencei

Sequence statusi: Complete.

Q3B7S5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDQYVSTAPP RFPIAQLGTF KQDSAGMGRI FKGNLLQKKA LTTFENEHHI
60 70 80 90 100
RFFTLLVLFH VMVLLRNHSR IQGVSEDWKR ANSIFRNFLR LKSSRNTAEA

E
Length:101
Mass (Da):11,722
Last modified:November 22, 2005 - v1
Checksum:i82E93FA8AFB9C6C7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC107486 mRNA. Translation: AAI07487.1.
CCDSiCCDS32845.1.
RefSeqiNP_001032408.1. NM_001037331.2.
UniGeneiHs.666744.

Genome annotation databases

EnsembliENST00000579022; ENSP00000462106; ENSG00000206026.
GeneIDi284274.
KEGGihsa:284274.
UCSCiuc002lma.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC107486 mRNA. Translation: AAI07487.1 .
CCDSi CCDS32845.1.
RefSeqi NP_001032408.1. NM_001037331.2.
UniGenei Hs.666744.

3D structure databases

ProteinModelPortali Q3B7S5.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PaxDbi Q3B7S5.
PRIDEi Q3B7S5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000579022 ; ENSP00000462106 ; ENSG00000206026 .
GeneIDi 284274.
KEGGi hsa:284274.
UCSCi uc002lma.1. human.

Organism-specific databases

CTDi 284274.
GeneCardsi GC18M073122.
HGNCi HGNC:27598. SMIM21.
HPAi CAB034243.
HPA041686.
neXtProti NX_Q3B7S5.
PharmGKBi PA162378613.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG135016.
GeneTreei ENSGT00410000028836.
HOGENOMi HOG000111963.
InParanoidi Q3B7S5.
OMAi ENEHHIR.
OrthoDBi EOG7N63Q1.
PhylomeDBi Q3B7S5.

Miscellaneous databases

GenomeRNAii 284274.
NextBioi 94687.

Gene expression databases

Bgeei Q3B7S5.
CleanExi HS_C18orf62.
ExpressionAtlasi Q3B7S5. baseline and differential.
Genevestigatori Q3B7S5.

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Entry informationi

Entry nameiSMI21_HUMAN
AccessioniPrimary (citable) accession number: Q3B7S5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: November 22, 2005
Last modified: October 29, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 18
    Human chromosome 18: entries, gene names and cross-references to MIM

External Data

Dasty 3