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Protein

Small integral membrane protein 21

Gene

SMIM21

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Protein predictedi

Names & Taxonomyi

Protein namesi
Recommended name:
Small integral membrane protein 21
Gene namesi
Name:SMIM21
Synonyms:C18orf62
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 18

Organism-specific databases

EuPathDBiHostDB:ENSG00000206026.7
HGNCiHGNC:27598 SMIM21
neXtProtiNX_Q3B7S5

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei49 – 65HelicalSequence analysisAdd BLAST17

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000206026
PharmGKBiPA162378613

Polymorphism and mutation databases

BioMutaiSMIM21

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003407221 – 101Small integral membrane protein 21Add BLAST101

Proteomic databases

PaxDbiQ3B7S5
PRIDEiQ3B7S5
ProteomicsDBi61657

Expressioni

Gene expression databases

BgeeiENSG00000206026
CleanExiHS_C18orf62
ExpressionAtlasiQ3B7S5 baseline and differential
GenevisibleiQ3B7S5 HS

Organism-specific databases

HPAiHPA041686

Interactioni

Protein-protein interaction databases

BioGridi129814, 1 interactor
STRINGi9606.ENSP00000462106

Structurei

3D structure databases

ProteinModelPortaliQ3B7S5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410KGD9 Eukaryota
ENOG4110SDX LUCA
GeneTreeiENSGT00410000028836
HOGENOMiHOG000111963
InParanoidiQ3B7S5
OMAiQGVSEDW
OrthoDBiEOG091G16HP
PhylomeDBiQ3B7S5

Sequencei

Sequence statusi: Complete.

Q3B7S5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDQYVSTAPP RFPIAQLGTF KQDSAGMGRI FKGNLLQKKA LTTFENEHHI
60 70 80 90 100
RFFTLLVLFH VMVLLRNHSR IQGVSEDWKR ANSIFRNFLR LKSSRNTAEA

E
Length:101
Mass (Da):11,722
Last modified:November 22, 2005 - v1
Checksum:i82E93FA8AFB9C6C7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC107486 mRNA Translation: AAI07487.1
CCDSiCCDS32845.1
RefSeqiNP_001032408.1, NM_001037331.3
UniGeneiHs.666744

Genome annotation databases

EnsembliENST00000579022; ENSP00000462106; ENSG00000206026
GeneIDi284274
KEGGihsa:284274
UCSCiuc002lma.2 human

Similar proteinsi

Entry informationi

Entry nameiSMI21_HUMAN
AccessioniPrimary (citable) accession number: Q3B7S5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: November 22, 2005
Last modified: June 20, 2018
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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