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Q3B7S5 (SMI21_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Small integral membrane protein 21
Gene names
Name:SMIM21
Synonyms:C18orf62
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length101 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Membrane; Single-pass membrane protein Potential.

Ontologies

Keywords
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 101101Small integral membrane protein 21
PRO_0000340722

Regions

Transmembrane49 – 6517Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q3B7S5 [UniParc].

Last modified November 22, 2005. Version 1.
Checksum: 82E93FA8AFB9C6C7

FASTA10111,722
        10         20         30         40         50         60 
MDQYVSTAPP RFPIAQLGTF KQDSAGMGRI FKGNLLQKKA LTTFENEHHI RFFTLLVLFH 

        70         80         90        100 
VMVLLRNHSR IQGVSEDWKR ANSIFRNFLR LKSSRNTAEA E 

« Hide

References

[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC107486 mRNA. Translation: AAI07487.1.
RefSeqNP_001032408.1. NM_001037331.2.
UniGeneHs.666744.

3D structure databases

ProteinModelPortalQ3B7S5.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PaxDbQ3B7S5.
PRIDEQ3B7S5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000579022; ENSP00000462106; ENSG00000206026.
GeneID284274.
KEGGhsa:284274.
UCSCuc002lma.1. human.

Organism-specific databases

CTD284274.
GeneCardsGC18M073122.
HGNCHGNC:27598. SMIM21.
HPACAB034243.
HPA041686.
neXtProtNX_Q3B7S5.
PharmGKBPA162378613.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG135016.
HOGENOMHOG000111963.
InParanoidQ3B7S5.
OMAENEHHIR.
OrthoDBEOG7N63Q1.

Gene expression databases

ArrayExpressQ3B7S5.
BgeeQ3B7S5.
CleanExHS_C18orf62.
GenevestigatorQ3B7S5.

Family and domain databases

ProtoNetSearch...

Other

GenomeRNAi284274.
NextBio94687.

Entry information

Entry nameSMI21_HUMAN
AccessionPrimary (citable) accession number: Q3B7S5
Entry history
Integrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: November 22, 2005
Last modified: February 19, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Human chromosome 18

Human chromosome 18: entries, gene names and cross-references to MIM