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Protein
Submitted name:

Ubiquitin A-52 residue ribosomal protein fusion product 1

Gene

uba52

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal proteinImported

Enzyme and pathway databases

ReactomeiR-DRE-110312. Translesion synthesis by REV1.
R-DRE-110314. Recognition of DNA damage by PCNA-containing replication complex.
R-DRE-110320. Translesion Synthesis by POLH.
R-DRE-1169091. Activation of NF-kappaB in B cells.
R-DRE-1227986. Signaling by ERBB2.
R-DRE-1234176. Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha.
R-DRE-1295596. Spry regulation of FGF signaling.
R-DRE-1358803. Downregulation of ERBB2:ERBB3 signaling.
R-DRE-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-DRE-168638. NOD1/2 Signaling Pathway.
R-DRE-174048. APC/C:Cdc20 mediated degradation of Cyclin B.
R-DRE-174084. Autodegradation of Cdh1 by Cdh1:APC/C.
R-DRE-174154. APC/C:Cdc20 mediated degradation of Securin.
R-DRE-174178. APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1.
R-DRE-174184. Cdc20:Phospho-APC/C mediated degradation of Cyclin A.
R-DRE-179409. APC-Cdc20 mediated degradation of Nek2A.
R-DRE-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-DRE-182971. EGFR downregulation.
R-DRE-187577. SCF(Skp2)-mediated degradation of p27/p21.
R-DRE-195253. Degradation of beta-catenin by the destruction complex.
R-DRE-201681. TCF dependent signaling in response to WNT.
R-DRE-202424. Downstream TCR signaling.
R-DRE-209543. p75NTR recruits signalling complexes.
R-DRE-209560. NF-kB is activated and signals survival.
R-DRE-2122948. Activated NOTCH1 Transmits Signal to the Nucleus.
R-DRE-2173788. Downregulation of TGF-beta receptor signaling.
R-DRE-2173791. TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition).
R-DRE-2173795. Downregulation of SMAD2/3:SMAD4 transcriptional activity.
R-DRE-2173796. SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription.
R-DRE-2467813. Separation of Sister Chromatids.
R-DRE-2559580. Oxidative Stress Induced Senescence.
R-DRE-2559582. Senescence-Associated Secretory Phenotype (SASP).
R-DRE-2559585. Oncogene Induced Senescence.
R-DRE-2565942. Regulation of PLK1 Activity at G2/M Transition.
R-DRE-2871837. FCERI mediated NF-kB activation.
R-DRE-3134975. Regulation of innate immune responses to cytosolic DNA.
R-DRE-349425. Autodegradation of the E3 ubiquitin ligase COP1.
R-DRE-3769402. Deactivation of the beta-catenin transactivating complex.
R-DRE-445989. TAK1 activates NFkB by phosphorylation and activation of IKKs complex.
R-DRE-446652. Interleukin-1 signaling.
R-DRE-450302. activated TAK1 mediates p38 MAPK activation.
R-DRE-450321. JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1.
R-DRE-450408. AUF1 (hnRNP D0) binds and destabilizes mRNA.
R-DRE-4608870. Asymmetric localization of PCP proteins.
R-DRE-4641257. Degradation of AXIN.
R-DRE-4641258. Degradation of DVL.
R-DRE-4641263. Regulation of FZD by ubiquitination.
R-DRE-5205685. Pink/Parkin Mediated Mitophagy.
R-DRE-5357905. Regulation of TNFR1 signaling.
R-DRE-5357956. TNFR1-induced NFkappaB signaling pathway.
R-DRE-5358346. Hedgehog ligand biogenesis.
R-DRE-5607761. Dectin-1 mediated noncanonical NF-kB signaling.
R-DRE-5607764. CLEC7A (Dectin-1) signaling.
R-DRE-5610785. GLI3 is processed to GLI3R by the proteasome.
R-DRE-5632684. Hedgehog 'on' state.
R-DRE-5654726. Negative regulation of FGFR1 signaling.
R-DRE-5654727. Negative regulation of FGFR2 signaling.
R-DRE-5654732. Negative regulation of FGFR3 signaling.
R-DRE-5654733. Negative regulation of FGFR4 signaling.
R-DRE-5655862. Translesion synthesis by POLK.
R-DRE-5656121. Translesion synthesis by POLI.
R-DRE-5656169. Termination of translesion DNA synthesis.
R-DRE-5658442. Regulation of RAS by GAPs.
R-DRE-5668541. TNFR2 non-canonical NF-kB pathway.
R-DRE-5675221. Negative regulation of MAPK pathway.
R-DRE-5675482. Regulation of necroptotic cell death.
R-DRE-5676590. NIK-->noncanonical NF-kB signaling.
R-DRE-5684264. MAP3K8 (TPL2)-dependent MAPK1/3 activation.
R-DRE-5685942. HDR through Homologous Recombination (HRR).
R-DRE-5687128. MAPK6/MAPK4 signaling.
R-DRE-5693565. Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks.
R-DRE-5696394. DNA Damage Recognition in GG-NER.
R-DRE-5696395. Formation of Incision Complex in GG-NER.
R-DRE-5696397. Gap-filling DNA repair synthesis and ligation in GG-NER.
R-DRE-5696400. Dual Incision in GG-NER.
R-DRE-6781823. Formation of TC-NER Pre-Incision Complex.
R-DRE-6782135. Dual incision in TC-NER.
R-DRE-6782210. Gap-filling DNA repair synthesis and ligation in TC-NER.
R-DRE-6783310. Fanconi Anemia Pathway.
R-DRE-68827. CDT1 association with the CDC6:ORC:origin complex.
R-DRE-68949. Orc1 removal from chromatin.
R-DRE-69017. CDK-mediated phosphorylation and removal of Cdc6.
R-DRE-69229. Ubiquitin-dependent degradation of Cyclin D1.
R-DRE-69231. Cyclin D associated events in G1.
R-DRE-69298. Association of licensing factors with the pre-replicative complex.
R-DRE-69601. Ubiquitin Mediated Degradation of Phosphorylated Cdc25A.
R-DRE-72689. Formation of a pool of free 40S subunits.
R-DRE-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-DRE-912631. Regulation of signaling by CBL.
R-DRE-917729. Endosomal Sorting Complex Required For Transport (ESCRT).
R-DRE-937042. IRAK2 mediated activation of TAK1 complex.
R-DRE-937072. TRAF6 mediated induction of TAK1 complex.
R-DRE-975163. IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation.
R-DRE-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-DRE-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
R-DRE-983168. Antigen processing: Ubiquitination & Proteasome degradation.

Names & Taxonomyi

Protein namesi
Submitted name:
Ubiquitin A-52 residue ribosomal protein fusion product 1Imported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:uba52Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 2

Organism-specific databases

ZFINiZDB-GENE-051023-7. uba52.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000060744.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 7676Ubiquitin-likeInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG0003. Eukaryota.
COG1552. LUCA.
COG5272. LUCA.
GeneTreeiENSGT00840000129851.
HOGENOMiHOG000233942.
HOVERGENiHBG052927.
KOiK02927.
OMAiKTKCGHT.
OrthoDBiEOG7JDR1W.
TreeFamiTF352129.

Family and domain databases

InterProiIPR001975. Ribosomal_L40e.
IPR011332. Ribosomal_zn-bd.
IPR019956. Ubiquitin.
IPR029071. Ubiquitin-rel_dom.
IPR019954. Ubiquitin_CS.
IPR000626. Ubiquitin_dom.
[Graphical view]
PfamiPF01020. Ribosomal_L40e. 1 hit.
PF00240. ubiquitin. 1 hit.
[Graphical view]
PRINTSiPR00348. UBIQUITIN.
SMARTiSM01377. Ribosomal_L40e. 1 hit.
SM00213. UBQ. 1 hit.
[Graphical view]
SUPFAMiSSF54236. SSF54236. 1 hit.
SSF57829. SSF57829. 1 hit.
PROSITEiPS00299. UBIQUITIN_1. 1 hit.
PS50053. UBIQUITIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3B7P7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQIFVKTLTG KTITLEVEPS DTIENVKAKI QDKEGIPPDQ QRLIFAGKQL
60 70 80 90 100
EDGRTLSDYN IQKESTLHLV LRLRGGIIEP SLRQLAQKYN CEKMICRKCY
110 120
ARLHPRAVNC RKKKCGHTNN LRPKKKLK
Length:128
Mass (Da):14,756
Last modified:November 22, 2005 - v1
Checksum:i7BDE802ABF51CA9A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU693374 Genomic DNA. No translation available.
BC105746 mRNA. Translation: AAI05747.1.
BC107517 mRNA. Translation: AAI07518.1.
RefSeqiNP_001032190.1. NM_001037113.1.
UniGeneiDr.35198.

Genome annotation databases

EnsembliENSDART00000060745; ENSDARP00000060744; ENSDARG00000041435.
GeneIDi641289.
KEGGidre:641289.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU693374 Genomic DNA. No translation available.
BC105746 mRNA. Translation: AAI05747.1.
BC107517 mRNA. Translation: AAI07518.1.
RefSeqiNP_001032190.1. NM_001037113.1.
UniGeneiDr.35198.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000060744.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000060745; ENSDARP00000060744; ENSDARG00000041435.
GeneIDi641289.
KEGGidre:641289.

Organism-specific databases

CTDi7311.
ZFINiZDB-GENE-051023-7. uba52.

Phylogenomic databases

eggNOGiKOG0003. Eukaryota.
COG1552. LUCA.
COG5272. LUCA.
GeneTreeiENSGT00840000129851.
HOGENOMiHOG000233942.
HOVERGENiHBG052927.
KOiK02927.
OMAiKTKCGHT.
OrthoDBiEOG7JDR1W.
TreeFamiTF352129.

Enzyme and pathway databases

ReactomeiR-DRE-110312. Translesion synthesis by REV1.
R-DRE-110314. Recognition of DNA damage by PCNA-containing replication complex.
R-DRE-110320. Translesion Synthesis by POLH.
R-DRE-1169091. Activation of NF-kappaB in B cells.
R-DRE-1227986. Signaling by ERBB2.
R-DRE-1234176. Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha.
R-DRE-1295596. Spry regulation of FGF signaling.
R-DRE-1358803. Downregulation of ERBB2:ERBB3 signaling.
R-DRE-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-DRE-168638. NOD1/2 Signaling Pathway.
R-DRE-174048. APC/C:Cdc20 mediated degradation of Cyclin B.
R-DRE-174084. Autodegradation of Cdh1 by Cdh1:APC/C.
R-DRE-174154. APC/C:Cdc20 mediated degradation of Securin.
R-DRE-174178. APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1.
R-DRE-174184. Cdc20:Phospho-APC/C mediated degradation of Cyclin A.
R-DRE-179409. APC-Cdc20 mediated degradation of Nek2A.
R-DRE-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-DRE-182971. EGFR downregulation.
R-DRE-187577. SCF(Skp2)-mediated degradation of p27/p21.
R-DRE-195253. Degradation of beta-catenin by the destruction complex.
R-DRE-201681. TCF dependent signaling in response to WNT.
R-DRE-202424. Downstream TCR signaling.
R-DRE-209543. p75NTR recruits signalling complexes.
R-DRE-209560. NF-kB is activated and signals survival.
R-DRE-2122948. Activated NOTCH1 Transmits Signal to the Nucleus.
R-DRE-2173788. Downregulation of TGF-beta receptor signaling.
R-DRE-2173791. TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition).
R-DRE-2173795. Downregulation of SMAD2/3:SMAD4 transcriptional activity.
R-DRE-2173796. SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription.
R-DRE-2467813. Separation of Sister Chromatids.
R-DRE-2559580. Oxidative Stress Induced Senescence.
R-DRE-2559582. Senescence-Associated Secretory Phenotype (SASP).
R-DRE-2559585. Oncogene Induced Senescence.
R-DRE-2565942. Regulation of PLK1 Activity at G2/M Transition.
R-DRE-2871837. FCERI mediated NF-kB activation.
R-DRE-3134975. Regulation of innate immune responses to cytosolic DNA.
R-DRE-349425. Autodegradation of the E3 ubiquitin ligase COP1.
R-DRE-3769402. Deactivation of the beta-catenin transactivating complex.
R-DRE-445989. TAK1 activates NFkB by phosphorylation and activation of IKKs complex.
R-DRE-446652. Interleukin-1 signaling.
R-DRE-450302. activated TAK1 mediates p38 MAPK activation.
R-DRE-450321. JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1.
R-DRE-450408. AUF1 (hnRNP D0) binds and destabilizes mRNA.
R-DRE-4608870. Asymmetric localization of PCP proteins.
R-DRE-4641257. Degradation of AXIN.
R-DRE-4641258. Degradation of DVL.
R-DRE-4641263. Regulation of FZD by ubiquitination.
R-DRE-5205685. Pink/Parkin Mediated Mitophagy.
R-DRE-5357905. Regulation of TNFR1 signaling.
R-DRE-5357956. TNFR1-induced NFkappaB signaling pathway.
R-DRE-5358346. Hedgehog ligand biogenesis.
R-DRE-5607761. Dectin-1 mediated noncanonical NF-kB signaling.
R-DRE-5607764. CLEC7A (Dectin-1) signaling.
R-DRE-5610785. GLI3 is processed to GLI3R by the proteasome.
R-DRE-5632684. Hedgehog 'on' state.
R-DRE-5654726. Negative regulation of FGFR1 signaling.
R-DRE-5654727. Negative regulation of FGFR2 signaling.
R-DRE-5654732. Negative regulation of FGFR3 signaling.
R-DRE-5654733. Negative regulation of FGFR4 signaling.
R-DRE-5655862. Translesion synthesis by POLK.
R-DRE-5656121. Translesion synthesis by POLI.
R-DRE-5656169. Termination of translesion DNA synthesis.
R-DRE-5658442. Regulation of RAS by GAPs.
R-DRE-5668541. TNFR2 non-canonical NF-kB pathway.
R-DRE-5675221. Negative regulation of MAPK pathway.
R-DRE-5675482. Regulation of necroptotic cell death.
R-DRE-5676590. NIK-->noncanonical NF-kB signaling.
R-DRE-5684264. MAP3K8 (TPL2)-dependent MAPK1/3 activation.
R-DRE-5685942. HDR through Homologous Recombination (HRR).
R-DRE-5687128. MAPK6/MAPK4 signaling.
R-DRE-5693565. Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks.
R-DRE-5696394. DNA Damage Recognition in GG-NER.
R-DRE-5696395. Formation of Incision Complex in GG-NER.
R-DRE-5696397. Gap-filling DNA repair synthesis and ligation in GG-NER.
R-DRE-5696400. Dual Incision in GG-NER.
R-DRE-6781823. Formation of TC-NER Pre-Incision Complex.
R-DRE-6782135. Dual incision in TC-NER.
R-DRE-6782210. Gap-filling DNA repair synthesis and ligation in TC-NER.
R-DRE-6783310. Fanconi Anemia Pathway.
R-DRE-68827. CDT1 association with the CDC6:ORC:origin complex.
R-DRE-68949. Orc1 removal from chromatin.
R-DRE-69017. CDK-mediated phosphorylation and removal of Cdc6.
R-DRE-69229. Ubiquitin-dependent degradation of Cyclin D1.
R-DRE-69231. Cyclin D associated events in G1.
R-DRE-69298. Association of licensing factors with the pre-replicative complex.
R-DRE-69601. Ubiquitin Mediated Degradation of Phosphorylated Cdc25A.
R-DRE-72689. Formation of a pool of free 40S subunits.
R-DRE-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-DRE-912631. Regulation of signaling by CBL.
R-DRE-917729. Endosomal Sorting Complex Required For Transport (ESCRT).
R-DRE-937042. IRAK2 mediated activation of TAK1 complex.
R-DRE-937072. TRAF6 mediated induction of TAK1 complex.
R-DRE-975163. IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation.
R-DRE-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-DRE-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
R-DRE-983168. Antigen processing: Ubiquitination & Proteasome degradation.

Miscellaneous databases

NextBioi20901518.

Family and domain databases

InterProiIPR001975. Ribosomal_L40e.
IPR011332. Ribosomal_zn-bd.
IPR019956. Ubiquitin.
IPR029071. Ubiquitin-rel_dom.
IPR019954. Ubiquitin_CS.
IPR000626. Ubiquitin_dom.
[Graphical view]
PfamiPF01020. Ribosomal_L40e. 1 hit.
PF00240. ubiquitin. 1 hit.
[Graphical view]
PRINTSiPR00348. UBIQUITIN.
SMARTiSM01377. Ribosomal_L40e. 1 hit.
SM00213. UBQ. 1 hit.
[Graphical view]
SUPFAMiSSF54236. SSF54236. 1 hit.
SSF57829. SSF57829. 1 hit.
PROSITEiPS00299. UBIQUITIN_1. 1 hit.
PS50053. UBIQUITIN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: LiverImported.
  2. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: LarvaeImported.
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: TuebingenImported.
  4. "The zebrafish reference genome sequence and its relationship to the human genome."
    Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
    , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G., Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
    Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TuebingenImported.

Entry informationi

Entry nameiQ3B7P7_DANRE
AccessioniPrimary (citable) accession number: Q3B7P7
Entry historyi
Integrated into UniProtKB/TrEMBL: November 22, 2005
Last sequence update: November 22, 2005
Last modified: May 11, 2016
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.