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Protein

RUN domain-containing protein 3B

Gene

Rundc3b

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
RUN domain-containing protein 3B
Gene namesi
Name:Rundc3b
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 4

Organism-specific databases

RGDi1587590. Rundc3b.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 403403RUN domain-containing protein 3BPRO_0000336053Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei211 – 2111PhosphoserineCombined sources
Modified residuei212 – 2121PhosphoserineCombined sources

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ3B7K9.

PTM databases

iPTMnetiQ3B7K9.

Expressioni

Gene expression databases

ExpressionAtlasiQ3B7K9. baseline and differential.
GenevisibleiQ3B7K9. RN.

Interactioni

Subunit structurei

Interacts with RAP2A.By similarity

Protein-protein interaction databases

BioGridi603416. 1 interaction.
STRINGi10116.ENSRNOP00000035622.

Structurei

3D structure databases

ProteinModelPortaliQ3B7K9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini53 – 185133RUNPROSITE-ProRule annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili296 – 32126Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the RUNDC3 family.Curated
Contains 1 RUN domain.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiKOG4381. Eukaryota.
ENOG410XRAX. LUCA.
GeneTreeiENSGT00550000074558.
HOGENOMiHOG000143407.
HOVERGENiHBG052747.
InParanoidiQ3B7K9.
OMAiTHLTNQW.
OrthoDBiEOG70CR6K.
PhylomeDBiQ3B7K9.
TreeFamiTF323904.

Family and domain databases

InterProiIPR004012. Run_dom.
[Graphical view]
PfamiPF02759. RUN. 1 hit.
[Graphical view]
SMARTiSM00593. RUN. 1 hit.
[Graphical view]
PROSITEiPS50826. RUN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3B7K9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASRSLGGLS GSRGGGKKSL SARNAAVERR NLITVCRFSV KTLIDRSCFE
60 70 80 90 100
TIDDSSPEFN NFAAVLEQIL SHRLKGQVTW FGYESPRSFW DYIRVACRKV
110 120 130 140 150
SQNCICSIEN MENVSSSRAK GRAWIRVALM EKHLSEYIST ALRDFKTTRR
160 170 180 190 200
FYEEGAIVLG EEANMLAGML LGLNAIDFSF CLKGEGLDGT FPAVIDYTPY
210 220 230 240 250
LKFEQSSDSI SSDEEELRTF GSSDSEGSTP ENVGPPLILD ENSWFNKCKR
260 270 280 290 300
VRQKYQLTLE QKGYLEELLR LRENQLSESV SQNKILLQRI EDSDLAHKLE
310 320 330 340 350
KEQLEYIIVE LQDQLKSYQS LDQLSAEVSL SQASLDPGHS QEGDGKQDSL
360 370 380 390 400
NFIGEGKEDT PSLLGLCGSL TSVASYKSLT SLKSNDCLAS PTTEITSPGL

TPS
Length:403
Mass (Da):44,792
Last modified:November 22, 2005 - v1
Checksum:iDFBA159914B9C037
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC107563 mRNA. Translation: AAI07564.1.
RefSeqiNP_001040581.1. NM_001047116.1.
UniGeneiRn.147469.

Genome annotation databases

EnsembliENSRNOT00000030224; ENSRNOP00000035622; ENSRNOG00000008463.
GeneIDi688590.
KEGGirno:688590.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC107563 mRNA. Translation: AAI07564.1.
RefSeqiNP_001040581.1. NM_001047116.1.
UniGeneiRn.147469.

3D structure databases

ProteinModelPortaliQ3B7K9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi603416. 1 interaction.
STRINGi10116.ENSRNOP00000035622.

PTM databases

iPTMnetiQ3B7K9.

Proteomic databases

PaxDbiQ3B7K9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000030224; ENSRNOP00000035622; ENSRNOG00000008463.
GeneIDi688590.
KEGGirno:688590.

Organism-specific databases

CTDi154661.
RGDi1587590. Rundc3b.

Phylogenomic databases

eggNOGiKOG4381. Eukaryota.
ENOG410XRAX. LUCA.
GeneTreeiENSGT00550000074558.
HOGENOMiHOG000143407.
HOVERGENiHBG052747.
InParanoidiQ3B7K9.
OMAiTHLTNQW.
OrthoDBiEOG70CR6K.
PhylomeDBiQ3B7K9.
TreeFamiTF323904.

Miscellaneous databases

PROiQ3B7K9.

Gene expression databases

ExpressionAtlasiQ3B7K9. baseline and differential.
GenevisibleiQ3B7K9. RN.

Family and domain databases

InterProiIPR004012. Run_dom.
[Graphical view]
PfamiPF02759. RUN. 1 hit.
[Graphical view]
SMARTiSM00593. RUN. 1 hit.
[Graphical view]
PROSITEiPS50826. RUN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Prostate.
  2. "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues."
    Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C., Olsen J.V.
    Nat. Commun. 3:876-876(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-211 AND SER-212, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiRUN3B_RAT
AccessioniPrimary (citable) accession number: Q3B7K9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: November 22, 2005
Last modified: June 8, 2016
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.