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Protein
Submitted name:

Uncharacterized protein

Gene

ube2c

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Ubl conjugation pathwayUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-DRE-141430. Inactivation of APC/C via direct inhibition of the APC/C complex.
R-DRE-174048. APC/C:Cdc20 mediated degradation of Cyclin B.
R-DRE-174084. Autodegradation of Cdh1 by Cdh1:APC/C.
R-DRE-174154. APC/C:Cdc20 mediated degradation of Securin.
R-DRE-174178. APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1.
R-DRE-174184. Cdc20:Phospho-APC/C mediated degradation of Cyclin A.
R-DRE-176407. Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase.
R-DRE-176408. Regulation of APC/C activators between G1/S and early anaphase.
R-DRE-176409. APC/C:Cdc20 mediated degradation of mitotic proteins.
R-DRE-176412. Phosphorylation of the APC/C.
R-DRE-179409. APC-Cdc20 mediated degradation of Nek2A.
R-DRE-2467813. Separation of Sister Chromatids.
R-DRE-2559582. Senescence-Associated Secretory Phenotype (SASP).

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Submitted name:
Zgc:123190Imported
Gene namesi
Name:ube2cImported
Synonyms:zgc:123190Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 6

Organism-specific databases

ZFINiZDB-GENE-051030-48. ube2c.

Expressioni

Gene expression databases

BgeeiENSDARG00000035770.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000078114.

Structurei

3D structure databases

SMRiQ3B745. Positions 30-169.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini32 – 159128UBIQUITIN_CONJUGAT_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the ubiquitin-conjugating enzyme family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0421. Eukaryota.
KOG4801. Eukaryota.
ENOG4111IGV. LUCA.
GeneTreeiENSGT00760000119350.
HOGENOMiHOG000233454.
HOVERGENiHBG063308.
KOiK06688.
OMAiELMQLMM.
OrthoDBiEOG091G0M7S.
PhylomeDBiQ3B745.

Family and domain databases

Gene3Di3.10.110.10. 1 hit.
InterProiIPR000608. UBQ-conjugat_E2.
IPR023313. UBQ-conjugating_AS.
IPR016135. UBQ-conjugating_enzyme/RWD.
[Graphical view]
PfamiPF00179. UQ_con. 1 hit.
[Graphical view]
SUPFAMiSSF54495. SSF54495. 1 hit.
PROSITEiPS00183. UBIQUITIN_CONJUGAT_1. 1 hit.
PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3B745-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASQNMDPAA ASTATLKGSE TSVTASKGSV SKRLQQELMT LMMSGDKGIS
60 70 80 90 100
AFPESDNLFK WIGTIDGAQG TVYEGLRYKL SLEFPSGYPY NAPRVKFITA
110 120 130 140 150
CFHPNVDENG IICLDILKDK WSALYDVRSI LLSIQSLLGE PNNDSPMNST
160 170
AAEMWDDQEA FKAHLHATYK N
Length:171
Mass (Da):18,777
Last modified:November 22, 2005 - v1
Checksum:i36D1E98E46388A21
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CABZ01041603 Genomic DNA. No translation available.
CABZ01041604 Genomic DNA. No translation available.
BC107825 mRNA. Translation: AAI07826.1.
RefSeqiNP_001032780.1. NM_001037691.2.
UniGeneiDr.52310.

Genome annotation databases

EnsembliENSDART00000051906; ENSDARP00000051905; ENSDARG00000035770.
GeneIDi566441.
KEGGidre:566441.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CABZ01041603 Genomic DNA. No translation available.
CABZ01041604 Genomic DNA. No translation available.
BC107825 mRNA. Translation: AAI07826.1.
RefSeqiNP_001032780.1. NM_001037691.2.
UniGeneiDr.52310.

3D structure databases

SMRiQ3B745. Positions 30-169.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000078114.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000051906; ENSDARP00000051905; ENSDARG00000035770.
GeneIDi566441.
KEGGidre:566441.

Organism-specific databases

CTDi11065.
ZFINiZDB-GENE-051030-48. ube2c.

Phylogenomic databases

eggNOGiKOG0421. Eukaryota.
KOG4801. Eukaryota.
ENOG4111IGV. LUCA.
GeneTreeiENSGT00760000119350.
HOGENOMiHOG000233454.
HOVERGENiHBG063308.
KOiK06688.
OMAiELMQLMM.
OrthoDBiEOG091G0M7S.
PhylomeDBiQ3B745.

Enzyme and pathway databases

ReactomeiR-DRE-141430. Inactivation of APC/C via direct inhibition of the APC/C complex.
R-DRE-174048. APC/C:Cdc20 mediated degradation of Cyclin B.
R-DRE-174084. Autodegradation of Cdh1 by Cdh1:APC/C.
R-DRE-174154. APC/C:Cdc20 mediated degradation of Securin.
R-DRE-174178. APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1.
R-DRE-174184. Cdc20:Phospho-APC/C mediated degradation of Cyclin A.
R-DRE-176407. Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase.
R-DRE-176408. Regulation of APC/C activators between G1/S and early anaphase.
R-DRE-176409. APC/C:Cdc20 mediated degradation of mitotic proteins.
R-DRE-176412. Phosphorylation of the APC/C.
R-DRE-179409. APC-Cdc20 mediated degradation of Nek2A.
R-DRE-2467813. Separation of Sister Chromatids.
R-DRE-2559582. Senescence-Associated Secretory Phenotype (SASP).

Gene expression databases

BgeeiENSDARG00000035770.

Family and domain databases

Gene3Di3.10.110.10. 1 hit.
InterProiIPR000608. UBQ-conjugat_E2.
IPR023313. UBQ-conjugating_AS.
IPR016135. UBQ-conjugating_enzyme/RWD.
[Graphical view]
PfamiPF00179. UQ_con. 1 hit.
[Graphical view]
SUPFAMiSSF54495. SSF54495. 1 hit.
PROSITEiPS00183. UBIQUITIN_CONJUGAT_1. 1 hit.
PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ3B745_DANRE
AccessioniPrimary (citable) accession number: Q3B745
Entry historyi
Integrated into UniProtKB/TrEMBL: November 22, 2005
Last sequence update: November 22, 2005
Last modified: September 7, 2016
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.