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Protein

Glycine--tRNA ligase

Gene

glyQS

Organism
Chlorobium luteolum (strain DSM 273 / 2530) (Pelodictyon luteolum)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the attachment of glycine to tRNA(Gly).UniRule annotationSAAS annotation

Catalytic activityi

ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly).UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei113SubstrateUniRule annotation1
Binding sitei202SubstrateUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi234 – 236ATPUniRule annotation3
Nucleotide bindingi244 – 249ATPUniRule annotation6
Nucleotide bindingi317 – 318ATPUniRule annotation2
Nucleotide bindingi361 – 364ATPUniRule annotation4

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetaseUniRule annotationSAAS annotationImported, Ligase

Keywords - Biological processi

Protein biosynthesisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glycine--tRNA ligaseUniRule annotationSAAS annotation (EC:6.1.1.14UniRule annotationSAAS annotation)
Alternative name(s):
Glycyl-tRNA synthetaseUniRule annotation
Gene namesi
Name:glyQSUniRule annotation
Ordered Locus Names:Plut_0017Imported
OrganismiChlorobium luteolum (strain DSM 273 / 2530) (Pelodictyon luteolum)Imported
Taxonomic identifieri319225 [NCBI]
Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobium/Pelodictyon groupPelodictyon
Proteomesi
  • UP000002709 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homodimer.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi319225.Plut_0017.

Structurei

3D structure databases

ProteinModelPortaliQ3B6X2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini17 – 391AA_TRNA_LIGASE_IIInterPro annotationAdd BLAST375

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni249 – 253Substrate bindingUniRule annotation5
Regioni357 – 361Substrate bindingUniRule annotation5

Sequence similaritiesi

Belongs to the class-II aminoacyl-tRNA synthetase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105D9H. Bacteria.
COG0423. LUCA.
HOGENOMiHOG000242016.
KOiK01880.
OMAiQGSEWGE.
OrthoDBiPOG091H082X.

Family and domain databases

CDDicd00774. GlyRS-like_core. 1 hit.
Gene3Di3.40.50.800. 1 hit.
HAMAPiMF_00253_B. Gly_tRNA_synth_B. 1 hit.
InterProiIPR002314. aa-tRNA-synt_IIb.
IPR006195. aa-tRNA-synth_II.
IPR004154. Anticodon-bd.
IPR027031. Gly-tRNA_synthase/POLG2.
IPR022961. Gly_tRNA_ligase_bac.
IPR033731. GlyRS-like_core.
IPR002315. tRNA-synt_gly.
[Graphical view]
PANTHERiPTHR10745. PTHR10745. 1 hit.
PfamiPF03129. HGTP_anticodon. 1 hit.
PF00587. tRNA-synt_2b. 1 hit.
[Graphical view]
PRINTSiPR01043. TRNASYNTHGLY.
SUPFAMiSSF52954. SSF52954. 1 hit.
TIGRFAMsiTIGR00389. glyS_dimeric. 1 hit.
PROSITEiPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3B6X2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTPDTTRVQ GTSLSPDKVM HKLVSLAKRR GFIFPSSEIY GGLSSCFDYG
60 70 80 90 100
PLGSEMKRNI KELWWNAMTR RHQNIVGIDA SIMMNPTVWE ASGHVASFND
110 120 130 140 150
PMIDDRTTKR RYRADHLIEN HIEKLRRDGK DADALRVQMT YEACGASEEP
160 170 180 190 200
NRALYELIID EGIKAPDTGS GDWTEVRQFN LMFQCNMGAV ADSSGVVYLR
210 220 230 240 250
PETAQGIFVN FHNVRESSRM KVPFGIAQIG KAFRNEIVKG NFIFRMVEFE
260 270 280 290 300
QMEMQYFVKP GTQAEAFEAW REERYQWYTR QLGIRPEKLH WYKHDKLAHY
310 320 330 340 350
ADLAYDIKFE FPFGIEEIEG IHSRTDFDLS RHQEYSGKNM EYVDQVTNER
360 370 380 390 400
FIPYVVETSA GCDRLFLAIL SDAYSEDVVD GEERVVLKLA PKVAPVKAAV
410 420 430 440 450
LPLMKKGGMG EAAMKLRDEL AESFPVQYDD AASIGKRYRR QDEIGTPFCI
460 470 480
TVDHQSIEDG TVTVRFRDTA QQERIDMSQT AAFITAKMA
Length:489
Mass (Da):55,930
Last modified:November 22, 2005 - v1
Checksum:i2A90D33EA9A8A171
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000096 Genomic DNA. Translation: ABB22909.1.
RefSeqiWP_011356785.1. NC_007512.1.

Genome annotation databases

EnsemblBacteriaiABB22909; ABB22909; Plut_0017.
KEGGiplt:Plut_0017.
PATRICi21377432. VBIChlLut1287_0018.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000096 Genomic DNA. Translation: ABB22909.1.
RefSeqiWP_011356785.1. NC_007512.1.

3D structure databases

ProteinModelPortaliQ3B6X2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi319225.Plut_0017.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABB22909; ABB22909; Plut_0017.
KEGGiplt:Plut_0017.
PATRICi21377432. VBIChlLut1287_0018.

Phylogenomic databases

eggNOGiENOG4105D9H. Bacteria.
COG0423. LUCA.
HOGENOMiHOG000242016.
KOiK01880.
OMAiQGSEWGE.
OrthoDBiPOG091H082X.

Family and domain databases

CDDicd00774. GlyRS-like_core. 1 hit.
Gene3Di3.40.50.800. 1 hit.
HAMAPiMF_00253_B. Gly_tRNA_synth_B. 1 hit.
InterProiIPR002314. aa-tRNA-synt_IIb.
IPR006195. aa-tRNA-synth_II.
IPR004154. Anticodon-bd.
IPR027031. Gly-tRNA_synthase/POLG2.
IPR022961. Gly_tRNA_ligase_bac.
IPR033731. GlyRS-like_core.
IPR002315. tRNA-synt_gly.
[Graphical view]
PANTHERiPTHR10745. PTHR10745. 1 hit.
PfamiPF03129. HGTP_anticodon. 1 hit.
PF00587. tRNA-synt_2b. 1 hit.
[Graphical view]
PRINTSiPR01043. TRNASYNTHGLY.
SUPFAMiSSF52954. SSF52954. 1 hit.
TIGRFAMsiTIGR00389. glyS_dimeric. 1 hit.
PROSITEiPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ3B6X2_CHLL7
AccessioniPrimary (citable) accession number: Q3B6X2
Entry historyi
Integrated into UniProtKB/TrEMBL: November 22, 2005
Last sequence update: November 22, 2005
Last modified: November 2, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.