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Q3B5P9 (UPPP_PELLD) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Ordered Locus Names:Plut_0444
OrganismPelodictyon luteolum (strain DSM 273) (Chlorobium luteolum (strain DSM 273)) [Complete proteome] [HAMAP]
Taxonomic identifier319225 [NCBI]
Taxonomic lineageBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobium/Pelodictyon groupPelodictyon

Protein attributes

Sequence length282 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 282282Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000227625

Regions

Transmembrane1 – 2121Helical; Potential
Transmembrane39 – 5921Helical; Potential
Transmembrane85 – 10521Helical; Potential
Transmembrane115 – 13521Helical; Potential
Transmembrane153 – 17321Helical; Potential
Transmembrane193 – 21321Helical; Potential
Transmembrane229 – 24921Helical; Potential
Transmembrane259 – 27921Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q3B5P9 [UniParc].

Last modified November 22, 2005. Version 1.
Checksum: 434A7EDED0EE94DE

FASTA28230,122
        10         20         30         40         50         60 
MTLIQAILLG IIQGLTEFLP ISSTAHLRII PALAGWEDPG AAFTAIIQIG TLGAVMLYFR 

        70         80         90        100        110        120 
RDILSIVKSV ATGLWKGNPL HDGEAKMGWM IAAGTLPIVA FGLLFKHEIE TTLRSLYWIS 

       130        140        150        160        170        180 
GALIILALVL SLAEWKIKKR LEEGHPLKSM EDIGWKEALL IGLAQAIALI PGSSRSGTTI 

       190        200        210        220        230        240 
TGGLLLNLSR ETAARFSFLL SLPAVFAAGA FELYKTWDLI TADPGNIMNL AVATITSGIV 

       250        260        270        280 
GYLSIAFLLN YLKSHTTSIF IAYRLAAGAG LLLLLGGGTI LP 

« Hide

References

[1]"Complete sequence of Pelodictyon luteolum DSM 273."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Bryant D., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P.
Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 273.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000096 Genomic DNA. Translation: ABB23332.1.
RefSeqYP_374375.1. NC_007512.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING319225.Plut_0444.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABB23332; ABB23332; Plut_0444.
GeneID3745961.
KEGGplt:Plut_0444.
PATRIC21378358. VBIChlLut1287_0464.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218357.
KOK06153.
OMAAQCFALI.
OrthoDBEOG6QP13M.
ProtClustDBPRK12554.

Enzyme and pathway databases

BioCycPLUT319225:GHDM-456-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP_PELLD
AccessionPrimary (citable) accession number: Q3B5P9
Entry history
Integrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: November 22, 2005
Last modified: February 19, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families