Q3B3A1 (SYD_PELLD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Aspartate--tRNA ligase
EC=6.1.1.12

Alternative name(s):
Aspartyl-tRNA synthetase
Short name=AspRS

Gene names

Name:	aspS
Ordered Locus Names:	Plut_1320

Organism

Pelodictyon luteolum (strain DSM 273) (Chlorobium luteolum (strain DSM 273)) [Complete proteome] [HAMAP]

Taxonomic identifier

319225 [NCBI]

Taxonomic lineage

Bacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobium/Pelodictyon group › Pelodictyon

Protein attributes

Sequence length	604 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp). HAMAP MF_00044_B
Subunit structure	Homodimer By similarity. HAMAP MF_00044_B
Subcellular location	Cytoplasm HAMAP MF_00044_B.
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tRNA aminoacylation for protein translation Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW aspartate-tRNA ligase activity Inferred from electronic annotation. Source: EC nucleic acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 604	604	Aspartate--tRNA ligase HAMAP MF_00044_B		PRO_0000235541

Sequences

	Sequence		Length	Mass (Da)
	Q3B3A1 [UniParc]. Last modified November 22, 2005. Version 1. Checksum: A758EC4E1A46612F	FASTA	604	68,791
	10 20 30 40 50 60 MTKEAGELNA LKNRFRTDYC GQLGLDGEGR EVRLGGWVHR IRDHGGLVFI DLRDHTGICQ 70 80 90 100 110 120 LVVQPEREEL FELAGRLHAE SVITIEGRVV ARSSETINPR LASGSIEVVV SAIGVESHAR 130 140 150 160 170 180 PLPFPVADEV QTSEELRLKY RFIDLRREKI HENIIFRSRI SAAIRRYLEE RDFIEIQTPI 190 200 210 220 230 240 LTSSSPEGAR DFLVPSRLHP GKFYALPQAP QQFKQLLMVA GFPRYFQIAP CFRDEDARAD 250 260 270 280 290 300 RSPGEFYQLD MEMAFIEQDD LFEILEGMFR HLTDTMSKKR ITRFPFPRIS YREVMDSYGT 310 320 330 340 350 360 DKPDLRIPLK IEDVTPMFTD SGFKVFASNT KPGCAVKALV LKGRGTESRL FYDKAEKRAR 370 380 390 400 410 420 ELGSAGLAYI QFREEGPKGP IVKFMTEPEL QAMKDQLTLE TGDVVFFAAG KWEAACKIMG 430 440 450 460 470 480 GMRTYFGDLF TLDPDELSFC WIVDFPMFEY NEDAKKVDFS HNPFSMPQGE MEALETMDPL 490 500 510 520 530 540 DVLAYQYDIV CNGIELSSGA IRNHKPEIMY KAFEIAGYSR EEVDLRFGHM IEAFKLGAPP 550 560 570 580 590 600 HGGIAPGLDR LVMILRDEQN IREVIAFPMN QQAQDLMMAA PSEVTGAQLR ELHIRLDLPE EEKK

References

[1]

"Complete sequence of Pelodictyon luteolum DSM 273." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Bryant D., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P. Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 273.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000096 Genomic DNA. Translation: ABB24180.1.
RefSeq	YP_375223.1. NC_007512.1.
3D structure databases
ProteinModelPortal	Q3B3A1.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3B3A1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3744170.
GenomeReviews	Gene locus Plut_1320 in contig CP000096_GR.
KEGG	plt:Plut_1320.
NMPDR	fig|319225.3.peg.1288.
PATRIC	21380262. VBIChlLut1287_1390.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0173.
HOGENOM	HBG396032.
OMA	YQLDVEM.
PhylomeDB	Q3B3A1.
ProtClustDB	PRK00476.
Enzyme and pathway databases
BioCyc	PLUT319225:PLUT_1320-MONOMER.
Family and domain databases
HAMAP	MF_00044_B. Asp_tRNA_synth_B. [Tree]
InterPro	IPR004364. aa-tRNA-synt_II. IPR018150. aa-tRNA-synt_II-like. IPR006195. aa-tRNA-synth_II. IPR004524. Asp-tRNA-synth_IIb_bac/mt. IPR002312. Asp/Asn-tRNA-synth_IIb. IPR004115. GAD_dom. IPR012340. NA-bd_OB-fold. IPR016027. NA-bd_OB-fold-like. IPR004365. NA-bd_OB_tRNA-helicase. [Graphical view]
Gene3D	G3DSA:3.30.1360.30. GAD_dom. 1 hit. G3DSA:2.40.50.140. OB_NA_bd_sub. 1 hit.
KO	K01876.
PANTHER	PTHR22594. aa-tRNA-synt_II. 1 hit. PTHR22594:SF5. AspS_bac. 1 hit.
Pfam	PF02938. GAD. 1 hit. PF00152. tRNA-synt_2. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
PRINTS	PR01042. TRNASYNTHASP.
SUPFAM	SSF50249. Nucleic_acid_OB. 1 hit. SSF55261. SSF55261. 1 hit.
TIGRFAMs	TIGR00459. AspS_bact. 1 hit.
PROSITE	PS50862. AA_TRNA_LIGASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYD_PELLD

Accession

Primary (citable) accession number: Q3B3A1

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 16, 2006
Last sequence update:	November 22, 2005
Last modified:	January 25, 2012
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program