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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Pelodictyon luteolum (strain DSM 273) (Chlorobium luteolum (strain DSM 273))
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathway: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate.UniRule annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Phosphoglycerate kinase (pgk)
  3. 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (gpmA)
  4. Enolase (eno)
  5. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei37 – 371SubstrateUniRule annotation
Binding sitei119 – 1191SubstrateUniRule annotation
Binding sitei152 – 1521SubstrateUniRule annotation
Binding sitei203 – 2031ATPUniRule annotation
Binding sitei294 – 2941ATP; via carbonyl oxygenUniRule annotation
Binding sitei325 – 3251ATPUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi354 – 3574ATPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPLUT319225:GHDM-2127-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
Name:pgkUniRule annotation
Ordered Locus Names:Plut_2123
OrganismiPelodictyon luteolum (strain DSM 273) (Chlorobium luteolum (strain DSM 273))
Taxonomic identifieri319225 [NCBI]
Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobium/Pelodictyon groupPelodictyon
ProteomesiUP000002709 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 397397Phosphoglycerate kinasePRO_1000058024Add
BLAST

Proteomic databases

PRIDEiQ3B116.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi319225.Plut_2123.

Structurei

3D structure databases

ProteinModelPortaliQ3B116.
SMRiQ3B116. Positions 2-396.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni21 – 233Substrate bindingUniRule annotation
Regioni60 – 634Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227108.
KOiK00927.
OMAiDAFGTCH.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3B116-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQKKTLSDIT IQGKRVLMRV DFNVPLDGNG EITDDKRIVE ALPSIRKVLD
60 70 80 90 100
NGGRLILMSH LGRPKGKVNP DFSLTPVALR LSELIDTPVI MAGDCIGTEV
110 120 130 140 150
MQQALALQDG EVLLLENLRF HPEEEANDPE FSRELASLGE IYVNDAFGTA
160 170 180 190 200
HRAHASTEGI THFVQTAVAG YLIEKELMYL GKALQSPERP FVAILGGSKI
210 220 230 240 250
SGKIDVIDNL FSKVDTVLVG GAMVFTFFKA QGLETGRSLV EDNKTELALE
260 270 280 290 300
LLAKAKSMGV RLILPEDVMA APEISPDAPF HAVSVDQLAE NEMGVDIGPK
310 320 330 340 350
TAETYRKEIL GAKTVLWNGP MGVFEIDNFA GGTIAVAEAL AAATAKGATT
360 370 380 390
IIGGGDSAAA VAKAGLADKM THISTGGGAS LEFLEGKELP GIAALNG
Length:397
Mass (Da):42,087
Last modified:November 22, 2005 - v1
Checksum:i1F94F1DF3F79A539
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000096 Genomic DNA. Translation: ABB24965.1.
RefSeqiWP_011358835.1. NC_007512.1.
YP_376008.1. NC_007512.1.

Genome annotation databases

EnsemblBacteriaiABB24965; ABB24965; Plut_2123.
KEGGiplt:Plut_2123.
PATRICi21381914. VBIChlLut1287_2204.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000096 Genomic DNA. Translation: ABB24965.1.
RefSeqiWP_011358835.1. NC_007512.1.
YP_376008.1. NC_007512.1.

3D structure databases

ProteinModelPortaliQ3B116.
SMRiQ3B116. Positions 2-396.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi319225.Plut_2123.

Proteomic databases

PRIDEiQ3B116.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABB24965; ABB24965; Plut_2123.
KEGGiplt:Plut_2123.
PATRICi21381914. VBIChlLut1287_2204.

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227108.
KOiK00927.
OMAiDAFGTCH.
OrthoDBiEOG64N9Z0.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00185.
BioCyciPLUT319225:GHDM-2127-MONOMER.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Pelodictyon luteolum DSM 273."
    US DOE Joint Genome Institute
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Bryant D., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P.
    Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 273.

Entry informationi

Entry nameiPGK_PELLD
AccessioniPrimary (citable) accession number: Q3B116
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 22, 2005
Last modified: May 27, 2015
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.