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Q3AZZ7 (UPPP_SYNS9) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Ordered Locus Names:Syncc9902_0358
OrganismSynechococcus sp. (strain CC9902) [Complete proteome] [HAMAP]
Taxonomic identifier316279 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechococcus

Protein attributes

Sequence length283 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 283283Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000250273

Regions

Transmembrane46 – 6621Helical; Potential
Transmembrane95 – 11521Helical; Potential
Transmembrane127 – 14721Helical; Potential
Transmembrane154 – 17421Helical; Potential
Transmembrane200 – 22021Helical; Potential
Transmembrane227 – 24721Helical; Potential
Transmembrane259 – 27921Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q3AZZ7 [UniParc].

Last modified November 22, 2005. Version 1.
Checksum: 287B341DB6592274

FASTA28329,891
        10         20         30         40         50         60 
MIDTTAPLSL LEALVLGIVQ GLTEFLPISS TAHLRVVPAL LGWDDPGVSV TAAIQLGSVA 

        70         80         90        100        110        120 
AVIAYFRRDL TQVLTGISRA VRHGQWRDPD ARLGVAMVIG TLPILVLGLG IKFFWHAGYA 

       130        140        150        160        170        180 
SSPLRSVPSI AIVSIVMALF LAMAECMGPR LKQLGGVTGR DGFVVGLAQA LAVIPGVSRS 

       190        200        210        220        230        240 
GSTLTASLFD GWNRADAARF SFLLGIPAIS IAGLVELKSA LSTSAGAGPL PLLVGIFSAA 

       250        260        270        280 
VVSWLAIDWL LRFLQRNSTW IFVGYRLVFG AGLLVWWAFK SAN 

« Hide

References

[1]"Complete sequence of Synechococcus sp. CC9902."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Martinez M., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P.
Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CC9902.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000097 Genomic DNA. Translation: ABB25330.1.
RefSeqYP_376374.1. NC_007513.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING316279.Syncc9902_0358.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABB25330; ABB25330; Syncc9902_0358.
GeneID3743572.
KEGGsye:Syncc9902_0358.
PATRIC23797791. VBISynSp76179_0369.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218357.
KOK06153.
OMAAQCFALI.
OrthoDBEOG6QP13M.
ProtClustDBPRK00281.

Enzyme and pathway databases

BioCycSSP316279:GJCI-363-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP_SYNS9
AccessionPrimary (citable) accession number: Q3AZZ7
Entry history
Integrated into UniProtKB/Swiss-Prot: September 19, 2006
Last sequence update: November 22, 2005
Last modified: February 19, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families