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Q3AXQ7 (Q3AXQ7_SYNS9) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase HAMAP MF_01840

Short name=Mg-protoporphyrin IX monomethyl ester oxidative cyclase HAMAP MF_01840
EC=1.14.13.81 HAMAP MF_01840
Gene names
Name:acsF HAMAP MF_01840
Ordered Locus Names:Syncc9902_1165
OrganismSynechococcus sp. (strain CC9902) [Complete proteome] [HAMAP] EMBL ABB26129.1
Taxonomic identifier316279 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaChroococcalesSynechococcus

Protein attributes

Sequence length362 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) By similarity. HAMAP MF_01840

Catalytic activity

131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + 2 H2O. HAMAP MF_01840

131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = divinylprotochlorophyllide + NADP+ + 2 H2O. HAMAP MF_01840

Magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O. HAMAP MF_01840

Cofactor

Iron By similarity. HAMAP MF_01840

Pathway

Porphyrin biosynthesis; chlorophyll biosynthesis (light-independent). HAMAP MF_01840

Sequence similarities

Belongs to the AcsF family. HAMAP MF_01840

Sequences

Sequence LengthMass (Da)Tools
Q3AXQ7 [UniParc].

Last modified November 22, 2005. Version 1.
Checksum: F738EC512B0EE191

FASTA36241,864
        10         20         30         40         50         60 
MEPMVPPTAV ANQTAESAVS TKDPVKDTIL TPRFYTTDFE AMAAMDLRPN EAELEAICEE 

        70         80         90        100        110        120 
FRKDYNRHHF VRNEEFDGAA DKLDPETRKV FVEFLEQSCT SEFSGFLLYK ELSRRIKTTN 

       130        140        150        160        170        180 
PLLAECFGHM ARDEARHAGF LNKSMSDFGM QLDLGFLTAS KNYTFFKPKF IFYATYLSEK 

       190        200        210        220        230        240 
IGYWRYIAIF RHLEKNPDSK IFPIFNFFEN WCQDENRHGD FFDALMKAQP DTVRGPVAKL 

       250        260        270        280        290        300 
WCRFFLLAVF ATMYVRDVAR KEFYESLGLD ARTYDKMVIE KTNDTSARVF PVVLDVNNKK 

       310        320        330        340        350        360 
FWIRLERLVN NNAALNAADA SDSPAPIKLI RKLPYWVANG AEMAKLFLMP AIDSSKYQPA 


VR 

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References

[1]"Complete sequence of Synechococcus sp. CC9902."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Martinez M., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P.
Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000097 Genomic DNA. Translation: ABB26129.1.
RefSeqYP_377173.1. NC_007513.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ3AXQ7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3742815.
GenomeReviewsGene locus Syncc9902_1165 in contig CP000097_GR.
KEGGsye:Syncc9902_1165.
PATRIC23799661. VBISynSp76179_1291.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGNOG10633.
HOGENOMHBG284843.
OMAHGDFFDA.
PhylomeDBQ3AXQ7.
ProtClustDBPRK13654.

Enzyme and pathway databases

BioCycSSP1131-1:SYNCC9902_1165-MONOMER.

Family and domain databases

HAMAPMF_01840. AcsF.
[Tree]
InterProIPR008434. AcsF.
IPR012347. Ferritin-rel.
IPR009078. Ferritin/RR-like.
IPR003251. Rubrerythrin.
[Graphical view]
Gene3DG3DSA:1.20.1260.10. Ferritin_rel. 1 hit.
KOK04035.
PfamPF02915. Rubrerythrin. 1 hit.
[Graphical view]
SUPFAMSSF47240. Ferritin/RR_like. 1 hit.
TIGRFAMsTIGR02029. AcsF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ3AXQ7_SYNS9
AccessionPrimary (citable) accession number: Q3AXQ7
Entry history
Integrated into UniProtKB/TrEMBL: November 22, 2005
Last sequence update: November 22, 2005
Last modified: December 14, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)