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Q3AXB7 (AROA_SYNS9) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-phosphoshikimate 1-carboxyvinyltransferase
EC=2.5.1.19
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase
Short name=EPSP synthase
Short name=EPSPS
Gene names
Name:aroA
Ordered Locus Names:Syncc9902_1326
OrganismSynechococcus sp. (strain CC9902) [Complete proteome] [HAMAP]
Taxonomic identifier316279 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length437 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210

Subunit structure

Monomer By similarity. HAMAP MF_00210

Subcellular location

Cytoplasm By similarity HAMAP MF_00210.

Sequence similarities

Belongs to the EPSP synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-phosphoshikimate 1-carboxyvinyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4374373-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210
PRO_0000325386

Sequences

Sequence LengthMass (Da)Tools
Q3AXB7 [UniParc].

Last modified November 22, 2005. Version 1.
Checksum: ACEDD71DAC5E0379

FASTA43745,748
        10         20         30         40         50         60 
MSASASRDLK TGGCLQGRVK VPGDKSISHR SLLFGAIAEG TTTIEGLLPA EDPISTAACL 

        70         80         90        100        110        120 
RAMGVGITPI EAGKIVTVEG VGLDGLQEPQ HILDCGNSGT TMRLMLGLLA GRAGRHFVLD 

       130        140        150        160        170        180 
GDASLRRRPM RRVGQPLASM GADVRGRDNG NLAPLAVQGT TLRGTIVGTP VASAQVKSAI 

       190        200        210        220        230        240 
LLAALTADGP TTVIEPSQSR DHSERMLRAF GANLEVGGEM GRHISVKPGA TLHGQTVVVP 

       250        260        270        280        290        300 
GDISSAAFWL VAGALVPGSD LTIENVGLNP TRTGILEVLD QMGANIEIVH PRDVAGEPVG 

       310        320        330        340        350        360 
DLRVKHGPLK PFQFGEEIMP RLVDEVPILS VAACFCDGES RISGASELRV KETDRLAVMA 

       370        380        390        400        410        420 
RQLKAMGAEI EEHEDGMTIR GGRPLRGTAL DSETDHRVAM SMAIAALMAS GPSTLARSEA 

       430 
AAVSYPTFWD DLARLHS

« Hide

References

[1]"Complete sequence of Synechococcus sp. CC9902."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Martinez M., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P.
Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CC9902.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000097 Genomic DNA. Translation: ABB26290.1.
RefSeqYP_377334.1. NC_007513.1.

3D structure databases

HSSPHSSP built from PDB template 2BJB based on UniProtKB P22487.
ProteinModelPortalQ3AXB7.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ3AXB7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3743150.
GenomeReviewsGene locus Syncc9902_1326 in contig CP000097_GR.
KEGGsye:Syncc9902_1326.
PATRIC23800025. VBISynSp76179_1472.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0128.
HOGENOMHBG646626.
OMAGEDPRST.
PhylomeDBQ3AXB7.
ProtClustDBPRK02427.

Enzyme and pathway databases

BioCycSSP1131-1:SYNCC9902_1326-MONOMER.

Family and domain databases

HAMAPMF_00210. EPSP_synth.
[Tree]
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
Gene3DG3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KOK00800.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01356. AroA. 1 hit.
PROSITEPS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROA_SYNS9
AccessionPrimary (citable) accession number: Q3AXB7
Entry history
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: November 22, 2005
Last modified: January 25, 2012
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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