Q3AWZ4 (SYGA_SYNS9) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glycine--tRNA ligase alpha subunit
EC=6.1.1.14

Alternative name(s):
Glycyl-tRNA synthetase alpha subunit
Short name=GlyRS

Gene names

Name:	glyQ
Ordered Locus Names:	Syncc9902_1561

Organism

Synechococcus sp. (strain CC9902) [Complete proteome] [HAMAP]

Taxonomic identifier

316279 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length	290 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP MF_00254
Subunit structure	Tetramer of two alpha and two beta subunits By similarity.
Subcellular location	Cytoplasm HAMAP MF_00254.
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycyl-tRNA aminoacylation Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW glycine-tRNA ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 290	290	Glycine--tRNA ligase alpha subunit HAMAP MF_00254		PRO_1000047519

Sequences

	Sequence		Length	Mass (Da)
	Q3AWZ4 [UniParc]. Last modified November 22, 2005. Version 1. Checksum: 0219585196BEA87E	FASTA	290	32,902
	10 20 30 40 50 60 MHFQDIIGTL NSFWANQGCL LLQPYDTEKG AGTMSPHTVL RAIGPEPWAV AYPEPCRRPT 70 80 90 100 110 120 DGRYGDNPNR AQHYFQYQVL IKPSPDAIQE TYLASLEALG IKAADHDIRF VEDNWESPTL 130 140 150 160 170 180 GAWGVGWEVW LDGMEVTQFT YFQQCGGLDC KPVSIEITYG LERLAMYLQD VESIWDLSWN 190 200 210 220 230 240 ADRKYGDIWL PFEKGQCKFN FEASNPDRLK QLFAIYEAEA SDLIHQQLPA PALDFVLKCS 250 260 270 280 290 HTFNLLEARG VISVTERTAT IGRIRNLARK VAEAWLVERE ALGFPLLPSN

References

[1]

"Complete sequence of Synechococcus sp. CC9902." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Martinez M., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P. Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CC9902.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000097 Genomic DNA. Translation: ABB26519.1.
RefSeq	YP_377563.1. NC_007513.1.
3D structure databases
HSSP	HSSP built from PDB template 1J5W based on UniProtKB Q9WY59.
ProteinModelPortal	Q3AWZ4.
SMR	Q3AWZ4. Positions 1-276.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3AWZ4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3742304.
GenomeReviews	Gene locus Syncc9902_1561 in contig CP000097_GR.
KEGG	sye:Syncc9902_1561.
PATRIC	23800571. VBISynSp76179_1737.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0752.
HOGENOM	HBG285316.
OMA	CRRPTDG.
PhylomeDB	Q3AWZ4.
ProtClustDB	PRK09348.
Enzyme and pathway databases
BioCyc	SSP1131-1:SYNCC9902_1561-MONOMER.
Family and domain databases
HAMAP	MF_00254. Gly_tRNA_synth_alpha. [Tree]
InterPro	IPR006194. Gly-tRNA-synth_II_heterodimer. IPR002310. Gly-tRNA_synth_IIc_asu. [Graphical view]
KO	K01878.
Pfam	PF02091. tRNA-synt_2e. 1 hit. [Graphical view]
PRINTS	PR01044. TRNASYNTHGA.
TIGRFAMs	TIGR00388. GlyQ. 1 hit.
PROSITE	PS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYGA_SYNS9

Accession

Primary (citable) accession number: Q3AWZ4

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	November 22, 2005
Last modified:	January 25, 2012
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program