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Q3AWM6

- SYE_SYNS9

UniProt

Q3AWM6 - SYE_SYNS9

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Protein
Glutamate--tRNA ligase
Gene
gltX, Syncc9902_1719
Organism
Synechococcus sp. (strain CC9902)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) By similarity.UniRule annotation

Catalytic activityi

ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei250 – 2501ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. glutamate-tRNA ligase activity Source: UniProtKB-HAMAP
  3. tRNA binding Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. glutamyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSSP316279:GJCI-1737-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate--tRNA ligase (EC:6.1.1.17)
Alternative name(s):
Glutamyl-tRNA synthetase
Short name:
GluRS
Gene namesi
Name:gltX
Ordered Locus Names:Syncc9902_1719
OrganismiSynechococcus sp. (strain CC9902)
Taxonomic identifieri316279 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechococcus
ProteomesiUP000002712: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 477477Glutamate--tRNA ligaseUniRule annotation
PRO_0000237410Add
BLAST

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi316279.Syncc9902_1719.

Structurei

3D structure databases

ProteinModelPortaliQ3AWM6.
SMRiQ3AWM6. Positions 1-476.

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi8 – 1811"HIGH" regionUniRule annotation
Add
BLAST
Motifi247 – 2515"KMSKS" regionUniRule annotation

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0008.
HOGENOMiHOG000252722.
KOiK01885.
OMAiKHYDGDF.
OrthoDBiEOG6DRPF7.

Family and domain databases

Gene3Di1.10.10.350. 1 hit.
1.10.1160.10. 1 hit.
3.40.50.620. 2 hits.
HAMAPiMF_00022_B. Glu_tRNA_synth_B.
InterProiIPR008925. aa-tRNA-synth_I_codon-bd.
IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
IPR001412. aa-tRNA-synth_I_CS.
IPR004527. Glu-tRNA-ligase_bac/mito.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERiPTHR10119. PTHR10119. 1 hit.
PfamiPF00749. tRNA-synt_1c. 1 hit.
[Graphical view]
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF48163. SSF48163. 1 hit.
TIGRFAMsiTIGR00464. gltX_bact. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3AWM6-1 [UniParc]FASTAAdd to Basket

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MVRVRLAPSP TGTLHIGTAR TAVFNWLYAK SQNGDFLLRI EDTDKERSKP    50
EFTQNILEGL QWLGIDWAED PVIQSERVAQ HRDAIRALLE KGLAYRCYAN 100
ESELATMRDA QKASNQPPRY DNRHRNLTKE QETAYQAEGR DAVIRFRIDD 150
DADIHWNDLV RGTMRWRGGD LGGDMVVARR APADQIGDPL YNLVVVVDDA 200
AMEITHVIRG EDHIANTAKQ LLLYEALGLP SPTFAHAPLI LNADGKKLSK 250
RDGVTSINEF RSMGYTAEAI ANYMTLLGWS VPEGMEERFT LREAADQFSF 300
DRVNKAGARF DWDKLNWLNA QVLHSWSSAQ LLDVLRPLWL KNGWTIPNDN 350
GWALELCELL GPSLTLLNDG LDQAAPFFEC PDLEDDGLKQ LQSEGAKAAI 400
SHLIDALQAE RWMGTDFDQA QTLLGDAAKA AGVKKGVMMK SLRAALLGRL 450
QGPDLLTTWS LLAKNSDDLP RLQRCLS 477
Length:477
Mass (Da):53,374
Last modified:November 22, 2005 - v1
Checksum:i7234DC0C436A8FEE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000097 Genomic DNA. Translation: ABB26677.1.
RefSeqiWP_011360485.1. NC_007513.1.
YP_377721.1. NC_007513.1.

Genome annotation databases

EnsemblBacteriaiABB26677; ABB26677; Syncc9902_1719.
GeneIDi3742953.
KEGGisye:Syncc9902_1719.
PATRICi23800919. VBISynSp76179_1909.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000097 Genomic DNA. Translation: ABB26677.1 .
RefSeqi WP_011360485.1. NC_007513.1.
YP_377721.1. NC_007513.1.

3D structure databases

ProteinModelPortali Q3AWM6.
SMRi Q3AWM6. Positions 1-476.
ModBasei Search...

Protein-protein interaction databases

STRINGi 316279.Syncc9902_1719.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABB26677 ; ABB26677 ; Syncc9902_1719 .
GeneIDi 3742953.
KEGGi sye:Syncc9902_1719.
PATRICi 23800919. VBISynSp76179_1909.

Phylogenomic databases

eggNOGi COG0008.
HOGENOMi HOG000252722.
KOi K01885.
OMAi KHYDGDF.
OrthoDBi EOG6DRPF7.

Enzyme and pathway databases

BioCyci SSP316279:GJCI-1737-MONOMER.

Family and domain databases

Gene3Di 1.10.10.350. 1 hit.
1.10.1160.10. 1 hit.
3.40.50.620. 2 hits.
HAMAPi MF_00022_B. Glu_tRNA_synth_B.
InterProi IPR008925. aa-tRNA-synth_I_codon-bd.
IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
IPR001412. aa-tRNA-synth_I_CS.
IPR004527. Glu-tRNA-ligase_bac/mito.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
PANTHERi PTHR10119. PTHR10119. 1 hit.
Pfami PF00749. tRNA-synt_1c. 1 hit.
[Graphical view ]
PRINTSi PR00987. TRNASYNTHGLU.
SUPFAMi SSF48163. SSF48163. 1 hit.
TIGRFAMsi TIGR00464. gltX_bact. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Synechococcus sp. CC9902."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Martinez M., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P.
    Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CC9902.

Entry informationi

Entry nameiSYE_SYNS9
AccessioniPrimary (citable) accession number: Q3AWM6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: November 22, 2005
Last modified: September 3, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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