Q3AUF1 (Q3AUF1_CHLCH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Chromosomal replication initiator protein DnaA HAMAP MF_00377

Gene names

Name:	dnaA HAMAP MF_00377
Ordered Locus Names:	Cag_0001

Organism

Chlorobium chlorochromatii (strain CaD3) [Complete proteome] [HAMAP]

Taxonomic identifier

340177 [NCBI]

Taxonomic lineage

Bacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobium/Pelodictyon group › Chlorobium

Protein attributes

Sequence length	492 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids By similarity. HAMAP MF_00377 RuleBase RU000577
Subcellular location	Cytoplasm By similarity HAMAP MF_00377.
Sequence similarities	Belongs to the DnaA family. HAMAP MF_00377 RuleBase RU004227

Ontologies

Keywords
Biological process	DNA replication HAMAP MF_00377 RuleBase RU000577
Cellular component	Cytoplasm HAMAP MF_00377
Ligand	ATP-binding HAMAP MF_00377 RuleBase RU000577 DNA-binding HAMAP MF_00377 RuleBase RU000577 Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA-dependent DNA replication initiation Inferred from electronic annotation. Source: HAMAP regulation of DNA replication Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP DNA replication origin binding Inferred from electronic annotation. Source: HAMAP nucleoside-triphosphatase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	194 – 201	8	ATP By similarity HAMAP MF_00377

Sequences

	Sequence		Length	Mass (Da)
	Q3AUF1 [UniParc]. Last modified November 22, 2005. Version 1. Checksum: 8E6B3399625037E1	FASTA	492	55,889
	10 20 30 40 50 60 MHDHSPILVT DPHSLKGQKQ SSMEQQVWDT CLAVIKESIN PLAFKTWFLP IRPLGFVGGE 70 80 90 100 110 120 LTIEVPSQFF YEWIEENYSL LLKQTLRDVI GSEARLMYSI VMDKSQGQPV TIELPQQTTS 130 140 150 160 170 180 PFTYEQAPLK VDRIEEQRHE SYERNVSRFE SHLNTKYIFD TLIRGDCNSL AFAAAKAVSQ 190 200 210 220 230 240 NPGQNAFNPL VIYGGVGLGK THMMQAVGNS VRENRLTDRV LYVSSEKFAI DFVNAIQNGK 250 260 270 280 290 300 IQEFSSFYRS IDVLIIDDIQ FFSGKEKTQE EIFHIFNTLH QSNKQIILSA DRPIKDIKGI 310 320 330 340 350 360 EDRLISRFNW GLSADIQPPD YETRKAIILS KLQHNGVTLD DAVIEFIATN VTENVRELEG 370 380 390 400 410 420 CIVKLLAAQS LDNRDIDLAF TKSTLKDIIR HTTKQLTLDT IEKGVSSYFS ITSNDLKGKS 430 440 450 460 470 480 KKKEIAVGRQ IAMYLAKMLT DSSLKTIGLH FGGRDHSTVI HAVSTISKRV EQISEERKRI 490 EEIKKRIEIL SM

References

[1]

"Complete sequence of Chlorobium chlorochromatii CaD3." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Bryant D., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P. Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CaD3.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000108 Genomic DNA. Translation: ABB27280.1.
RefSeq	YP_378323.1. NC_007514.1.
3D structure databases
ProteinModelPortal	Q3AUF1.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3AUF1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3747794.
GenomeReviews	Gene locus Cag_0001 in contig CP000108_GR.
KEGG	cch:Cag_0001.
PATRIC	21367521. VBIChlChl46571_0001.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0593.
HOGENOM	HBG695666.
OMA	DEVAFLI.
PhylomeDB	Q3AUF1.
ProtClustDB	PRK00149.
Family and domain databases
HAMAP	MF_00377. DnaA_bact. [Tree]
InterPro	IPR003593. ATPase_AAA+_core. IPR001957. Chromosome_initiator_DnaA. IPR020591. Chromosome_initiator_DnaA-like. IPR018312. Chromosome_initiator_DnaA_CS. IPR013159. DnaA_C. IPR013317. DnaA_Hda. IPR010921. Trp_repressor/repl_initiator. [Graphical view]
Gene3D	G3DSA:1.10.1750.10. DnaA_C. 1 hit.
KO	K02313.
Pfam	PF00308. Bac_DnaA. 1 hit. PF08299. Bac_DnaA_C. 1 hit. [Graphical view]
PRINTS	PR00051. DNAA.
SMART	SM00382. AAA. 1 hit. SM00760. Bac_DnaA_C. 1 hit. [Graphical view]
SUPFAM	SSF48295. Trp_repress_rep. 1 hit.
TIGRFAMs	TIGR00362. DnaA. 1 hit.
PROSITE	PS01008. DNAA. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q3AUF1_CHLCH

Accession

Primary (citable) accession number: Q3AUF1

Entry history

Integrated into UniProtKB/TrEMBL:	November 22, 2005
Last sequence update:	November 22, 2005
Last modified:	December 14, 2011
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)