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Q3ATT2 (KDSB_CHLCH) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-deoxy-manno-octulosonate cytidylyltransferase
EC=2.7.7.38
Alternative name(s):
CMP-2-keto-3-deoxyoctulosonic acid synthase
Short name=CKS
Short name=CMP-KDO synthase
Gene names
Name:kdsB
Ordered Locus Names:Cag_0320
OrganismChlorobium chlorochromatii (strain CaD3) [Complete proteome] [HAMAP]
Taxonomic identifier340177 [NCBI]
Taxonomic lineageBacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobium/Pelodictyon group › Chlorobium

Protein attributes

Sequence length248 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria By similarity. HAMAP MF_00057

Catalytic activity

CTP + 3-deoxy-D-manno-octulosonate = diphosphate + CMP-3-deoxy-D-manno-octulosonate. HAMAP MF_00057

Pathway

Nucleotide-sugar biosynthesis; CMP-3-deoxy-D-manno-octulosonate biosynthesis; CMP-3-deoxy-D-manno-octulosonate from 3-deoxy-D-manno-octulosonate and CTP: step 1/1. HAMAP MF_00057

Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis. HAMAP MF_00057

Subcellular location

Cytoplasm Potential HAMAP MF_00057.

Sequence similarities

Belongs to the KdsB family.

Ontologies

Keywords
   Biological processLipopolysaccharide biosynthesis
   Cellular componentCytoplasm
   Molecular functionNucleotidyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processlipopolysaccharide biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-deoxy-manno-octulosonate cytidylyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 2482483-deoxy-manno-octulosonate cytidylyltransferase HAMAP MF_00057
PRO_1000116884

Sequences

Sequence LengthMass (Da)Tools
Q3ATT2 [UniParc].

Last modified November 22, 2005. Version 1.
Checksum: A23FFEC97A8C8E03

FASTA24827,937
        10         20         30         40         50         60 
MNAIIIIPAR LGSTRLPEKM LADIEGEPLI VRTWRQAMQC CRASRVVVAT DSVKIAEVLT 

        70         80         90        100        110        120 
TYGAEVVMTS PEARCGSERI AEAARQFACD VVVNLQGDEP LISHETIDLA LEPFFSPNPP 

       130        140        150        160        170        180 
DCSTLVFPLQ PDDWAQLHDP NQVKVVLNRE GYALYFSRSP IPFQRNQLTS TQCYRHVGLY 

       190        200        210        220        230        240 
AFKAEVLQCF AALPPTMLEE AESLEQLRLL EHGYRIRCMV THDDQPGVNT AEDLELVRTL 


FKQRHQEA

« Hide

References

[1]"Complete sequence of Chlorobium chlorochromatii CaD3."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Bryant D., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P.
Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CaD3.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000108 Genomic DNA. Translation: ABB27593.1.
RefSeqYP_378636.1. NC_007514.1.

3D structure databases

ProteinModelPortalQ3ATT2.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ3ATT2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3748115.
GenomeReviewsGene locus Cag_0320 in contig CP000108_GR.
KEGGcch:Cag_0320.
PATRIC21368209. VBIChlChl46571_0335.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1212.
HOGENOMHBG637773.
OMAINVQADE.
PhylomeDBQ3ATT2.
ProtClustDBPRK05450.

Enzyme and pathway databases

BioCycCCHL340177:CAG_0320-MONOMER.

Family and domain databases

HAMAPMF_00057. CMP-KDO_synth.
[Tree]
InterProIPR003329. Cytidylyl_trans.
IPR004528. KdsB.
[Graphical view]
KOK00979.
PANTHERPTHR21485:SF4. PTHR21485:SF4. 1 hit.
PfamPF02348. CTP_transf_3. 1 hit.
[Graphical view]
TIGRFAMsTIGR00466. KdsB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameKDSB_CHLCH
AccessionPrimary (citable) accession number: Q3ATT2
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: November 22, 2005
Last modified: January 25, 2012
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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