Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Catalase-peroxidase

Gene

katG

Organism
Chlorobium chlorochromatii (strain CaD3)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.UniRule annotation

Catalytic activityi

Donor + H2O2 = oxidized donor + 2 H2O.UniRule annotation
2 H2O2 = O2 + 2 H2O.UniRule annotation

Cofactori

heme bUniRule annotationNote: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei93Transition state stabilizerUniRule annotation1
Active sitei97Proton acceptorUniRule annotation1
Metal bindingi260Iron (heme axial ligand)UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase, Peroxidase

Keywords - Biological processi

Hydrogen peroxide

Keywords - Ligandi

Heme, Iron, Metal-binding

Protein family/group databases

PeroxiBasei2669. CchCP01.

Names & Taxonomyi

Protein namesi
Recommended name:
Catalase-peroxidaseUniRule annotation (EC:1.11.1.21UniRule annotation)
Short name:
CPUniRule annotation
Alternative name(s):
Peroxidase/catalaseUniRule annotation
Gene namesi
Name:katGUniRule annotation
Ordered Locus Names:Cag_0386
OrganismiChlorobium chlorochromatii (strain CaD3)
Taxonomic identifieri340177 [NCBI]
Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobium/Pelodictyon groupChlorobium
Proteomesi
  • UP000002708 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003547571 – 733Catalase-peroxidaseAdd BLAST733

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Cross-linki96 ↔ 219Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-245)UniRule annotation
Cross-linki219 ↔ 245Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-96)UniRule annotation

Post-translational modificationi

The covalent Trp-Tyr-Met adduct is important for the catalase, but not the peroxidase activity of the enzyme.UniRule annotation

Interactioni

Subunit structurei

Homodimer or homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi340177.Cag_0386.

Structurei

3D structure databases

ProteinModelPortaliQ3ATL6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peroxidase family. Peroxidase/catalase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C1X. Bacteria.
COG0376. LUCA.
HOGENOMiHOG000218110.
KOiK03782.
OMAiIAEVYAC.
OrthoDBiPOG091H05R1.

Family and domain databases

HAMAPiMF_01961. Catal_peroxid. 1 hit.
InterProiIPR000763. Catalase_peroxidase.
IPR010255. Haem_peroxidase.
IPR002016. Haem_peroxidase_pln/fun/bac.
IPR019794. Peroxidases_AS.
IPR019793. Peroxidases_heam-ligand_BS.
[Graphical view]
PfamiPF00141. peroxidase. 2 hits.
[Graphical view]
PRINTSiPR00460. BPEROXIDASE.
PR00458. PEROXIDASE.
SUPFAMiSSF48113. SSF48113. 2 hits.
TIGRFAMsiTIGR00198. cat_per_HPI. 1 hit.
PROSITEiPS00435. PEROXIDASE_1. 1 hit.
PS00436. PEROXIDASE_2. 1 hit.
PS50873. PEROXIDASE_4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3ATL6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNEERKCPIT GATHKPSAEK GRSNHDWWPN QLNLKILHQH SALSNPMDKD
60 70 80 90 100
FNYAEEFKKL DLAAIKQDLY ALMTDSQEWW PADYGHYGPL FIRMAWHSAG
110 120 130 140 150
TYRTSDGRGG AGTGSQRFAP LNSWPDNANL DKARRLLWPI KQKYGRQISW
160 170 180 190 200
ADLMILTGNC ALESMGLKTF GFAGGREDIW EPEEDIYWGT EGEWLADKRY
210 220 230 240 250
SGERELEKPL AAVQMGLIYV NPEGPNGKPD PLAAAKDIRE TFARMAMNDE
260 270 280 290 300
ETVALIAGGH TFGKTHGAGD ASQVGPEPEA AGIEEQGLGW KNQYGTGKGK
310 320 330 340 350
DTITSGLEVI WTTTPTKWSN NFFWNLFGYE WELTKSPAGA YQWTPKYGVG
360 370 380 390 400
ANTVPDAHDP SKRHAPAMMT TDLALRFDPD YEKIARRYYE NPDQFADAFA
410 420 430 440 450
RAWFKLTHRD MGPRSRYRGA EVPVEELIWQ DTIPALDHEL IGADEIAALK
460 470 480 490 500
ATILASELSI AQLISTAWAS AATFRNSDKR GGANGARLRL APQKDWEVNQ
510 520 530 540 550
PDELQKVLQV LETIQTEFNA SRNDGKKVSL ADLIVLGGCA AIEAAAEKAG
560 570 580 590 600
YKVTVPFTPG RMDATQEETD AHSFAVLEPV ADGFRNYLKA KYSFSVEEML
610 620 630 640 650
IDKAQLLTLT APEMTVLIGG MRVLNTNAGH TTHGVFTKRP ETLSNDFFVN
660 670 680 690 700
LLDMGTVWKA TSEASDIFEG RNRSTGELQW TATRVDLVFG SNSQLRALVE
710 720 730
VYGCKDSQEK FLNDFIAAWN KVMNLDRFDL SGL
Length:733
Mass (Da):81,677
Last modified:November 22, 2005 - v1
Checksum:i353611606058E8DD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000108 Genomic DNA. Translation: ABB27659.1.
RefSeqiWP_011361432.1. NC_007514.1.

Genome annotation databases

EnsemblBacteriaiABB27659; ABB27659; Cag_0386.
KEGGicch:Cag_0386.
PATRICi21368355. VBIChlChl46571_0404.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000108 Genomic DNA. Translation: ABB27659.1.
RefSeqiWP_011361432.1. NC_007514.1.

3D structure databases

ProteinModelPortaliQ3ATL6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi340177.Cag_0386.

Protein family/group databases

PeroxiBasei2669. CchCP01.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABB27659; ABB27659; Cag_0386.
KEGGicch:Cag_0386.
PATRICi21368355. VBIChlChl46571_0404.

Phylogenomic databases

eggNOGiENOG4105C1X. Bacteria.
COG0376. LUCA.
HOGENOMiHOG000218110.
KOiK03782.
OMAiIAEVYAC.
OrthoDBiPOG091H05R1.

Family and domain databases

HAMAPiMF_01961. Catal_peroxid. 1 hit.
InterProiIPR000763. Catalase_peroxidase.
IPR010255. Haem_peroxidase.
IPR002016. Haem_peroxidase_pln/fun/bac.
IPR019794. Peroxidases_AS.
IPR019793. Peroxidases_heam-ligand_BS.
[Graphical view]
PfamiPF00141. peroxidase. 2 hits.
[Graphical view]
PRINTSiPR00460. BPEROXIDASE.
PR00458. PEROXIDASE.
SUPFAMiSSF48113. SSF48113. 2 hits.
TIGRFAMsiTIGR00198. cat_per_HPI. 1 hit.
PROSITEiPS00435. PEROXIDASE_1. 1 hit.
PS00436. PEROXIDASE_2. 1 hit.
PS50873. PEROXIDASE_4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiKATG_CHLCH
AccessioniPrimary (citable) accession number: Q3ATL6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 25, 2008
Last sequence update: November 22, 2005
Last modified: November 2, 2016
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.